GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy
Kasiewicz, Lisa N., Biswas, Souvik, Beach, Aaron, Ren, Huilan, Dutta, Chaitali, Mazzola, Anne Marie, Rohde, Ellen, Chadwick, Alexandra, Cheng, Christopher, Garcia, Sara P., Iyer, Sowmya, Matsumoto, Yuri, Khera, Amit V., Musunuru, Kiran, Kathiresan, Sekar, Malyala, Padma, Rajeev, Kallanthottathil G., Bellinger, Andrew M.
Published in Nature communications (15.05.2023)
Published in Nature communications (15.05.2023)
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Journal Article
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
Musunuru, Kiran, Chadwick, Alexandra C., Mizoguchi, Taiji, Garcia, Sara P., DeNizio, Jamie E., Reiss, Caroline W., Wang, Kui, Iyer, Sowmya, Dutta, Chaitali, Clendaniel, Victoria, Amaonye, Michael, Beach, Aaron, Berth, Kathleen, Biswas, Souvik, Braun, Maurine C., Chen, Huei-Mei, Colace, Thomas V., Ganey, John D., Gangopadhyay, Soumyashree A., Garrity, Ryan, Kasiewicz, Lisa N., Lavoie, Jennifer, Madsen, James A., Matsumoto, Yuri, Mazzola, Anne Marie, Nasrullah, Yusuf S., Nneji, Joseph, Ren, Huilan, Sanjeev, Athul, Shay, Madeleine, Stahley, Mary R., Fan, Steven H. Y., Tam, Ying K., Gaudelli, Nicole M., Ciaramella, Giuseppe, Stolz, Leslie E., Malyala, Padma, Cheng, Christopher J., Rajeev, Kallanthottathil G., Rohde, Ellen, Bellinger, Andrew M., Kathiresan, Sekar
Published in Nature (London) (20.05.2021)
Published in Nature (London) (20.05.2021)
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Journal Article
Lipid nanoparticles silence tumor necrosis factor α to improve wound healing in diabetic mice
Kasiewicz, Lisa N., Whitehead, Kathryn A.
Published in Bioengineering & translational medicine (01.01.2019)
Published in Bioengineering & translational medicine (01.01.2019)
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Journal Article
Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d
Chaudhary, Namit, Kasiewicz, Lisa N, Newby, Alexandra N, Arral, Mariah L, Yerneni, Saigopalakrishna S, Melamed, Jilian R, LoPresti, Samuel T, Fein, Katherine C, Strelkova Petersen, Daria M, Kumar, Sushant, Purwar, Rahul, Whitehead, Kathryn A
Published in Nature biomedical engineering (03.10.2024)
Published in Nature biomedical engineering (03.10.2024)
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Journal Article
표적화된 RNA 전달을 위한 조성물 및 방법
KASIEWICZ LISA N, BISWAS SOUVIK, RAJEEV KALLANTHOTTATHIL G, REISS CAROLINE, MALYALA PADMA, CHADWICK ALEXANDRA
Year of Publication 25.01.2023
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Year of Publication 25.01.2023
Patent
A method for reducing the risk of coronary disease
Kallanthottathil G Rajeev, Souvik Biswas, Alexandra Chadwick, N Lisa Kasiewicz, Padma Malyala, Caroline Reiss
Year of Publication 23.10.2024
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Year of Publication 23.10.2024
Patent
Compositions and methods for targeted RNA delivery
Kallanthottathil G Rajeev, Souvik Biswas, Alexandra Chadwick, N Lisa Kasiewicz, Padma Malyala, Caroline Reiss
Year of Publication 23.10.2024
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Year of Publication 23.10.2024
Patent
A method for reducing the risk of coronary disease
Kallanthottathil G Rajeev, Souvik Biswas, Alexandra Chadwick, N Lisa Kasiewicz, Padma Malyala, Caroline Reiss
Year of Publication 11.09.2024
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Year of Publication 11.09.2024
Patent
A method for reducing the risk of coronary disease
Kallanthottathil G Rajeev, Souvik Biswas, Alexandra Chadwick, N Lisa Kasiewicz, Padma Malyala, Caroline Reiss
Year of Publication 28.08.2024
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Year of Publication 28.08.2024
Patent
A method for reducing the risk of coronary disease
Kallanthottathil G Rajeev, Souvik Biswas, Alexandra Chadwick, N Lisa Kasiewicz, Padma Malyala, Caroline Reiss
Year of Publication 28.08.2024
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Year of Publication 28.08.2024
Patent
A method for reducing the risk of coronary disease
Kallanthottathil G Rajeev, Souvik Biswas, Alexandra Chadwick, N Lisa Kasiewicz, Padma Malyala, Caroline Reiss
Year of Publication 07.08.2024
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Year of Publication 07.08.2024
Patent
COMPOSITIONS AND METHODS FOR TARGETED RNA DELIVERY
KASIEWICZ, Lisa, N, REISS, Caroline, RAJEEV, Kallanthottathil, G, CHADWICK, Alexandra, MALYALA, Padma, BISWAS, Souvik
Year of Publication 26.06.2024
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Year of Publication 26.06.2024
Patent
COMPOSITIONS AND METHODS FOR TARGETED RNA DELIVERY
Kasiewicz, Lisa N, Chadwick, Alexandra, Reiss, Caroline, Malyala, Padma, Rajeev, Kallanthottathil G, Biswas, Souvik
Year of Publication 25.04.2024
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Year of Publication 25.04.2024
Patent
COMPOSITIONS AND METHODS FOR TARGETED RNA DELIVERY
Kasiewicz, Lisa N, Chadwick, Alexandra, Reiss, Caroline, Malyala, Padma, Rajeev, Kallanthottathil G, Biswas, Souvik
Year of Publication 28.03.2024
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Year of Publication 28.03.2024
Patent
A method for reducing the risk of coronary disease
Kallanthottathil G Rajeev, Souvik Biswas, Alexandra Chadwick, N Lisa Kasiewicz, Padma Malyala, Caroline Reiss
Year of Publication 21.02.2024
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Year of Publication 21.02.2024
Patent
LIPID FORMULATIONS FOR GENE EDITING
Kasiewicz, Lisa N, Malyala, Padma, Rajeev, Kallanthottathil G, Biswas, Souvik, Colace, Thomas V, Beach, Aaron
Year of Publication 11.01.2024
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Year of Publication 11.01.2024
Patent
Compositions and methods for targeted RNA delivery
Kallanthottathil G Rajeev, Souvik Biswas, Alexandra Chadwick, N Lisa Kasiewicz, Padma Malyala, Caroline Reiss
Year of Publication 03.01.2024
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Year of Publication 03.01.2024
Patent
COMPOSITIONS AND METHODS FOR TARGETED RNA DELIVERY
Kasiewicz, Lisa N, Chadwick, Alexandra, Reiss, Caroline, Malyala, Padma, Cheng, Christopher, Rajeev, Kallanthottathil G, Biswas, Souvik, Rohde, Ellen, Bellinger, Andrew
Year of Publication 26.09.2024
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Year of Publication 26.09.2024
Patent