Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease
Oliveira, Mauricio M, Lourenco, Mychael V, Longo, Francesco, Kasica, Nicole P, Yang, Wenzhong, Ureta, Gonzalo, Ferreira, Danielle D P, Mendonça, Paulo H J, Bernales, Sebastian, Ma, Tao, De Felice, Fernanda G, Klann, Eric, Ferreira, Sergio T
Published in Science signaling (02.02.2021)
Published in Science signaling (02.02.2021)
Get more information
Journal Article
Homozygous knockout of eEF2K alleviates cognitive deficits in APP/PS1 Alzheimer's disease model mice independent of brain amyloid β pathology
Kasica, Nicole P, Zhou, Xueyan, Jester, Hannah M, Holland, Caroline E, Ryazanov, Alexey G, Forshaw, Tom E, Furdui, Cristina M, Ma, Tao
Published in Frontiers in aging neuroscience (09.09.2022)
Published in Frontiers in aging neuroscience (09.09.2022)
Get full text
Journal Article
Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice
Beckelman, Brenna C, Yang, Wenzhong, Kasica, Nicole P, Zimmermann, Helena R, Zhou, Xueyan, Keene, C Dirk, Ryazanov, Alexey G, Ma, Tao
Published in The Journal of clinical investigation (01.02.2019)
Published in The Journal of clinical investigation (01.02.2019)
Get full text
Journal Article
Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer's model mice
Zimmermann, Helena R, Yang, Wenzhong, Kasica, Nicole P, Zhou, Xueyan, Wang, Xin, Beckelman, Brenna C, Lee, Jingyun, Furdui, Cristina M, Keene, C Dirk, Ma, Tao
Published in The Journal of clinical investigation (01.07.2020)
Published in The Journal of clinical investigation (01.07.2020)
Get full text
Journal Article
Antagonists targeting eEF2 kinase rescue multiple aspects of pathophysiology in Alzheimer’s disease model mice
Kasica, Nicole P., Zhou, Xueyan, Yang, Qian, Wang, Xin, Yang, Wenzhong, Zimmermann, Helena R., Holland, Caroline E., Koscielniak, Elizabeth, Wu, Hanzhi, Cox, Anderson O., Lee, Jingyun, Ryazanov, Alexey G., Furdui, Cristina M., Ma, Tao
Published in Journal of neurochemistry (01.03.2022)
Published in Journal of neurochemistry (01.03.2022)
Get full text
Journal Article
Genetic removal of eIF2α kinase PERK in mice enables hippocampal L‐LTP independent of mTORC1 activity
Zimmermann, Helena R., Yang, Wenzhong, Beckelman, Brenna C., Kasica, Nicole P., Zhou, Xueyan, Galli, Lucas Dufresne, Ryazanov, Alexey G., Ma, Tao
Published in Journal of neurochemistry (01.07.2018)
Published in Journal of neurochemistry (01.07.2018)
Get full text
Journal Article
Memory impairments in Tg19959 and APP/PS1 AD model mice are alleviated by eEF2K inhibitor A‐484954
Kasica, Nicole P, Yang, Wenzhong, Zhou, Xueyan, Ma, Tao
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
Get full text
Journal Article
Brain-specific repression of AMPK[alpha]1 alleviates pathophysiology in Alzheimer's model mice
Zimmermann, Helena R, Yang, Wenzhong, Kasica, Nicole P, Zhou, Xueyan, Wang, Xin, Beckelman, Brenna C, Lee, Jingyun, Furdui, Cristina M, Keene, C. Dirk, Ma, Tao
Published in The Journal of clinical investigation (01.07.2020)
Published in The Journal of clinical investigation (01.07.2020)
Get full text
Journal Article
Genetic removal of eIF 2α kinase PERK in mice enables hippocampal L‐ LTP independent of mTORC 1 activity
Zimmermann, Helena R., Yang, Wenzhong, Beckelman, Brenna C., Kasica, Nicole P., Zhou, Xueyan, Galli, Lucas Dufresne, Ryazanov, Alexey G., Ma, Tao
Published in Journal of neurochemistry (01.07.2018)
Published in Journal of neurochemistry (01.07.2018)
Get full text
Journal Article
Abstract 3187: Role of exosome secretion in the survival of enzalutamide-resistant prostate cancer cells: Syntaxin 6 as a novel therapeutic target
Peak, Taylor C., Kasica, Nicole P., Panigrahi, Gati K., Patterson, Sierra L., Singh, Ravi, Hemal, Ashok K., Bitting, Rhonda L., Deep, Gagan
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Antagonists targeting eEF2 kinase rescue multiple aspects of pathophysiology in Alzheimer's disease model mice
Kasica, Nicole P, Zhou, Xueyan, Wang, Xin, Yang, Wenzhong P, Zimmermann, Helena R, Holland, Caroline E, Koscielniak, Elizabeth, Wu, Hanzhi, Anderson O'brien Cox, Lee, Jingyun, Ryazanov, Alexey G, Furdui, Cristina M, Ma, Tao
Published in bioRxiv (15.07.2021)
Published in bioRxiv (15.07.2021)
Get full text
Paper
Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity and memory in mouse models of Alzheimer’s disease
Oliveira, Mauricio M, Lourenco, Mychael V, Longo, Francesco, Kasica, Nicole P, Yang, Wenzhong, Ureta, Gonzalo, Ferreira, Danielle D P, Mendonça, Paulo H J, Bernales, Sebastian, Ma, Tao, De Felice, Fernanda G, Klann, Eric, Ferreira, Sergio T
Published in bioRxiv (19.10.2020)
Published in bioRxiv (19.10.2020)
Get full text
Paper