Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing
Karunakaran, Mohindar M., Willcox, Carrie R., Salim, Mahboob, Paletta, Daniel, Fichtner, Alina S., Noll, Angela, Starick, Lisa, Nöhren, Anna, Begley, Charlotte R., Berwick, Katie A., Chaleil, Raphaël A.G., Pitard, Vincent, Déchanet-Merville, Julie, Bates, Paul A., Kimmel, Brigitte, Knowles, Timothy J., Kunzmann, Volker, Walter, Lutz, Jeeves, Mark, Mohammed, Fiyaz, Willcox, Benjamin E., Herrmann, Thomas
Published in Immunity (Cambridge, Mass.) (17.03.2020)
Published in Immunity (Cambridge, Mass.) (17.03.2020)
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A distinct topology of BTN3A IgV and B30.2 domains controlled by juxtamembrane regions favors optimal human γδ T cell phosphoantigen sensing
Karunakaran, Mohindar M., Subramanian, Hariharan, Jin, Yiming, Mohammed, Fiyaz, Kimmel, Brigitte, Juraske, Claudia, Starick, Lisa, Nöhren, Anna, Länder, Nora, Willcox, Carrie R., Singh, Rohit, Schamel, Wolfgang W., Nikolaev, Viacheslav O., Kunzmann, Volker, Wiemer, Andrew J., Willcox, Benjamin E., Herrmann, Thomas
Published in Nature communications (22.11.2023)
Published in Nature communications (22.11.2023)
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Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1
Willcox, Carrie R., Salim, Mahboob, Begley, Charlotte R., Karunakaran, Mohindar M., Easton, Emily J., von Klopotek, Carlotta, Berwick, Katie A., Herrmann, Thomas, Mohammed, Fiyaz, Jeeves, Mark, Willcox, Benjamin E.
Published in Cell reports (Cambridge) (25.04.2023)
Published in Cell reports (Cambridge) (25.04.2023)
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Vγ9Vδ2 TCR‐activation by phosphorylated antigens requires butyrophilin 3 A1 (BTN3A1) and additional genes on human chromosome 6
Riaño, Felipe, Karunakaran, Mohindar M., Starick, Lisa, Li, Jianqiang, Scholz, Claus J., Kunzmann, Volker, Olive, Daniel, Amslinger, Sabine, Herrmann, Thomas
Published in European journal of immunology (01.09.2014)
Published in European journal of immunology (01.09.2014)
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V gamma 9 and V delta 2 T cell antigen receptor genes and butyrophilin 3 (BTN3) emerged with placental mammals and are concomitantly preserved in selected species like alpaca (Vicugna pacos)
Karunakaran, Mohindar M, Gobel, Thomas W, Starick, Lisa, Walter, Lutz, Herrmann, Thomas
Published in Immunogenetics (New York) (01.04.2014)
Published in Immunogenetics (New York) (01.04.2014)
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Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive Vγ9Vδ2 T cell subset
Fichtner, Alina S., Karunakaran, Mohindar M., Gu, Siyi, Boughter, Christopher T., Borowska, Marta T., Starick, Lisa, Nöhren, Anna, Göbel, Thomas W., Adams, Erin J., Herrmann, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2020)
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Vγ9 and Vδ2 T cell antigen receptor genes and butyrophilin 3 (BTN3) emerged with placental mammals and are concomitantly preserved in selected species like alpaca (Vicugna pacos)
Karunakaran, Mohindar M., Göbel, Thomas W., Starick, Lisa, Walter, Lutz, Herrmann, Thomas
Published in Immunogenetics (New York) (01.04.2014)
Published in Immunogenetics (New York) (01.04.2014)
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Butyrophilin 3A (BTN3A, CD277)‐specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation
Starick, Lisa, Riano, Felipe, Karunakaran, Mohindar M., Kunzmann, Volker, Li, Jianqiang, Kreiss, Matthias, Amslinger, Sabine, Scotet, Emmanuel, Olive, Daniel, Libero, Gennaro, Herrmann, Thomas
Published in European journal of immunology (01.06.2017)
Published in European journal of immunology (01.06.2017)
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V[gamma]9V[delta]2 TCR-activation by phosphorylated antigens requires butyrophilin 3 A1 (BTN3A1) and additional genes on human chromosome 6
Riano, Felipe, Karunakaran, Mohindar M, Starick, Lisa, Li, Jianqiang, Scholz, Claus J, Kunzmann, Volker, Olive, Daniel, Amslinger, Sabine, Herrmann, Thomas
Published in European journal of immunology (01.09.2014)
Published in European journal of immunology (01.09.2014)
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Journal Article
V gamma 9V delta 2 TCR-activation by phosphorylated antigens requires butyrophilin 3 A1 ( BTN3A1 ) and additional genes on human chromosome 6
Riano, Felipe, Karunakaran, Mohindar M, Starick, Lisa, Li, Jianqiang, Scholz, Claus J, Kunzmann, Volker, Olive, Daniel, Amslinger, Sabine, Herrmann, Thomas
Published in European journal of immunology (01.09.2014)
Published in European journal of immunology (01.09.2014)
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Journal Article
V[gamma]9 and V[delta]2 T cell antigen receptor genes and butyrophilin 3 (BTN3) emerged with placental mammals and are concomitantly preserved in selected species like alpaca (Vicugna pacos)
Karunakaran, Mohindar M, Göbel, Thomas W, Starick, Lisa, Walter, Lutz, Herrmann, Thomas
Published in Immunogenetics (New York) (01.04.2014)
Published in Immunogenetics (New York) (01.04.2014)
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