Lack of Fibronectin-EDA Promotes Survival and Prevents Adverse Remodeling and Heart Function Deterioration After Myocardial Infarction
Arslan, Fatih, Smeets, Mirjam B, Riem Vis, Paul W, Karper, Jacco C, Quax, Paul H, Bongartz, Lennart G, Peters, John H, Hoefer, Imo E, Doevendans, Pieter A, Pasterkamp, Gerard, de Kleijn, Dominique P
Published in Circulation research (04.03.2011)
Published in Circulation research (04.03.2011)
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The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development
de Jong, Rob C M, Ewing, Mark M, de Vries, Margreet R, Karper, Jacco C, Bastiaansen, Antonius J N M, Peters, Hendrika A B, Baghana, Fabiana, van den Elsen, Peter J, Gongora, Céline, Jukema, J Wouter, Quax, Paul H A
Published in PloS one (10.10.2017)
Published in PloS one (10.10.2017)
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Editorial: Inflammation and immunomodulation in cardiovascular remodeling
Ewing, Mark, Karper, Jacco C, de Vries, Margreet R, Quax, Paul H A
Published in Frontiers in cardiovascular medicine (16.12.2022)
Published in Frontiers in cardiovascular medicine (16.12.2022)
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Journal Article
Blocking Toll-Like Receptors 7 and 9 Reduces Postinterventional Remodeling via Reduced Macrophage Activation, Foam Cell Formation, and Migration
Karper, Jacco C, Ewing, Mark M, Habets, Kim L.L, de Vries, Margreet R, Peters, Erna A.B, van Oeveren-Rietdijk, Annemarie M, de Boer, Hetty C, Hamming, Jaap F, Kuiper, Johan, Kandimalla, Ekambar R, La Monica, Nicola, Jukema, J Wouter, Quax, Paul H.A
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2012)
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Journal Article
TLR4 accessory molecule RP105 (CD180) regulates monocyte-driven arteriogenesis in a murine hind limb ischemia model
Bastiaansen, Antonius J N M, Karper, Jacco C, Wezel, Anouk, de Boer, Hetty C, Welten, Sabine M J, de Jong, Rob C M, Peters, Erna A B, de Vries, Margreet R, van Oeveren-Rietdijk, Annemarie M, van Zonneveld, Anton Jan, Hamming, Jaap F, Nossent, A Yaël, Quax, Paul H A
Published in PloS one (19.06.2014)
Published in PloS one (19.06.2014)
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Toll-Like Receptor 4 Is Involved in Human and Mouse Vein Graft Remodeling, and Local Gene Silencing Reduces Vein Graft Disease in Hypercholesterolemic APOE3Leiden Mice
Karper, Jacco C, de Vries, Margreet R, van den Brand, Ben T, Hoefer, Imo E, Fischer, Jens W, Jukema, J Wouter, Niessen, Hans W.M, Quax, Paul H.A
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2011)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2011)
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TLR accessory molecule RP105 (CD180) is involved in post-interventional vascular remodeling and soluble RP105 modulates neointima formation
Karper, Jacco C, Ewing, Mark M, de Vries, Margreet R, de Jager, Saskia C A, Peters, Erna A B, de Boer, Hetty C, van Zonneveld, Anton-Jan, Kuiper, Johan, Huizinga, Eric G, Brondijk, T Harma C, Jukema, J Wouter, Quax, Paul H A
Published in PloS one (02.07.2013)
Published in PloS one (02.07.2013)
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Genetically Determined ABO Blood Group and its Associations With Health and Disease
Groot, Hilde E., Villegas Sierra, Laura E., Said, M. Abdullah, Lipsic, Erik, Karper, Jacco C., van der Harst, Pim
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2020)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2020)
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In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase inhibitor
Eefting, Daniel, MD, de Vries, Margreet R., BSc, Grimbergen, Jos M., BSc, Karper, Jacco C., MSc, van Bockel, J. Hajo, MD, PhD, Quax, Paul H.A., PhD
Published in Journal of vascular surgery (01.02.2010)
Published in Journal of vascular surgery (01.02.2010)
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Human genetic determinants of the gut microbiome and their associations with health and disease: a phenome-wide association study
Groot, Hilde E., van de Vegte, Yordi J., Verweij, Niek, Lipsic, Erik, Karper, Jacco C., van der Harst, Pim
Published in Scientific reports (08.09.2020)
Published in Scientific reports (08.09.2020)
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Plasma interleukin 6 levels are associated with cardiac function after ST-elevation myocardial infarction
Groot, Hilde E., Al Ali, Lawien, van der Horst, Iwan C. C., Schurer, Remco A. J., van der Werf, Hindrik W., Lipsic, Erik, van Veldhuisen, Dirk J., Karper, Jacco C., van der Harst, Pim
Published in Clinical research in cardiology (01.06.2019)
Published in Clinical research in cardiology (01.06.2019)
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A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers
de Brouwer, Remco, te Rijdt, Wouter P, Hoorntje, Edgar T, Amin, Ahmad, Asselbergs, Folkert W, Cox, Moniek G P J, van der Heijden, Jeroen F, Hillege, Hans, Karper, Jacco C, Mahmoud, Belend, van der Meer, Peter, Oomen, Anton, te Riele, Anneline S J M, Silljé, Herman H W, Tan, Hanno L, van Tintelen, Jan Peter, van Veldhuisen, Dirk J, Westenbrink, Berend Daan, Wiesfeld, Ans C P, Willems, Tineke P, van der Zwaag, Paul A, Wilde, Arthur A M, de Boer, Rudolf A, van den Berg, Maarten P
Published in European heart journal (21.10.2023)
Published in European heart journal (21.10.2023)
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High-sensitivity C-reactive protein and long term reperfusion success of primary percutaneous intervention in ST-elevation myocardial infarction
Groot, Hilde E., Karper, Jacco C., Lipsic, Erik, van Veldhuisen, Dirk J., van der Horst, Iwan C.C., van der Harst, Pim
Published in International journal of cardiology (01.12.2017)
Published in International journal of cardiology (01.12.2017)
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RP105 deficiency attenuates early atherosclerosis via decreased monocyte influx in a CCR2 dependent manner
Wezel, Anouk, van der Velden, Daniël, Maassen, Johanna M, Lagraauw, H. Maxime, de Vries, Margreet R, Karper, Jacco C, Kuiper, Johan, Bot, Ilze, Quax, Paul H.A
Published in Atherosclerosis (01.01.2015)
Published in Atherosclerosis (01.01.2015)
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Journal Article
Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response
Wezel, Anouk, de Vries, Margreet R., Maassen, Johanna M., Kip, Peter, Peters, Erna A., Karper, Jacco C., Kuiper, Johan, Bot, Ilze, Quax, Paul H. A.
Published in Scientific reports (07.04.2016)
Published in Scientific reports (07.04.2016)
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Future potential biomarkers for postinterventional restenosis and accelerated atherosclerosis
Karper, Jacco C, Ewing, Mark M, Jukema, J Wouter, Quax, Paul HA
Published in Biomarkers in medicine (01.02.2012)
Published in Biomarkers in medicine (01.02.2012)
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Journal Article
Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect
Tadros, Rafik, Francis, Catherine, Xu, Xiao, Vermeer, Alexa M. C., Harper, Andrew R., Huurman, Roy, Kelu Bisabu, Ken, Walsh, Roddy, Hoorntje, Edgar T., te Rijdt, Wouter P., Buchan, Rachel J., van Velzen, Hannah G., van Slegtenhorst, Marjon A., Vermeulen, Jentien M., Offerhaus, Joost Allard, Bai, Wenjia, de Marvao, Antonio, Lahrouchi, Najim, Beekman, Leander, Karper, Jacco C., Veldink, Jan H., Kayvanpour, Elham, Pantazis, Antonis, Baksi, A. John, Whiffin, Nicola, Mazzarotto, Francesco, Sloane, Geraldine, Suzuki, Hideaki, Schneider-Luftman, Deborah, Elliott, Paul, Richard, Pascale, Ader, Flavie, Villard, Eric, Lichtner, Peter, Meitinger, Thomas, Tanck, Michael W. T., van Tintelen, J. Peter, Thain, Andrew, McCarty, David, Hegele, Robert A., Roberts, Jason D., Amyot, Julie, Dubé, Marie-Pierre, Cadrin-Tourigny, Julia, Giraldeau, Geneviève, L’Allier, Philippe L., Garceau, Patrick, Tardif, Jean-Claude, Boekholdt, S. Matthijs, Lumbers, R. Thomas, Asselbergs, Folkert W., Barton, Paul J. R., Cook, Stuart A., Prasad, Sanjay K., O’Regan, Declan P., van der Velden, Jolanda, Verweij, Karin J. H., Talajic, Mario, Lettre, Guillaume, Pinto, Yigal M., Meder, Benjamin, Charron, Philippe, de Boer, Rudolf A., Christiaans, Imke, Michels, Michelle, Wilde, Arthur A. M., Watkins, Hugh, Matthews, Paul M., Ware, James S., Bezzina, Connie R.
Published in Nature genetics (01.02.2021)
Published in Nature genetics (01.02.2021)
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