Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives
Arab, Juan P., Karpen, Saul J., Dawson, Paul A., Arrese, Marco, Trauner, Michael
Published in Hepatology (Baltimore, Md.) (01.01.2017)
Published in Hepatology (Baltimore, Md.) (01.01.2017)
Get full text
Journal Article
Biliary Atresia: Clinical and Research Challenges for the Twenty‐First Century
Bezerra, Jorge A., Wells, Rebecca G., Mack, Cara L., Karpen, Saul J., Hoofnagle, Jay H., Doo, Edward, Sokol, Ronald J.
Published in Hepatology (Baltimore, Md.) (01.09.2018)
Published in Hepatology (Baltimore, Md.) (01.09.2018)
Get full text
Journal Article
Randomized placebo‐controlled trial of losartan for pediatric NAFLD
Vos, Miriam B., Van Natta, Mark L., Blondet, Niviann M., Dasarathy, Srinivasan, Fishbein, Mark, Hertel, Paula, Jain, Ajay K., Karpen, Saul J., Lavine, Joel E., Mohammad, Saeed, Miriel, Laura A., Molleston, Jean P., Mouzaki, Marialena, Sanyal, Arun, Sharkey, Emily P., Schwimmer, Jeffrey B., Tonascia, James, Wilson, Laura A., Xanthakos, Stavra A.
Published in Hepatology (Baltimore, Md.) (01.08.2022)
Published in Hepatology (Baltimore, Md.) (01.08.2022)
Get full text
Journal Article
Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice
Rao, Anuradha, Kosters, Astrid, Mells, Jamie E, Zhang, Wujuan, Setchell, Kenneth D R, Amanso, Angelica M, Wynn, Grace M, Xu, Tianlei, Keller, Brad T, Yin, Hong, Banton, Sophia, Jones, Dean P, Wu, Hao, Dawson, Paul A, Karpen, Saul J
Published in Science translational medicine (21.09.2016)
Published in Science translational medicine (21.09.2016)
Get more information
Journal Article
Phytosterols promote liver injury and Kupffer cell activation in parenteral nutrition-associated liver disease
El Kasmi, Karim C, Anderson, Aimee L, Devereaux, Michael W, Vue, Padade M, Zhang, Wujuan, Setchell, Kenneth D R, Karpen, Saul J, Sokol, Ronald J
Published in Science translational medicine (09.10.2013)
Published in Science translational medicine (09.10.2013)
Get more information
Journal Article
Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury
Truong, Jennifer K., Bennett, Ashley L., Klindt, Caroline, Donepudi, Ajay C., Malla, Sudarshan R., Pachura, Kimberly J., Zaufel, Alex, Moustafa, Tarek, Dawson, Paul A., Karpen, Saul J.
Published in Journal of lipid research (01.09.2022)
Published in Journal of lipid research (01.09.2022)
Get full text
Journal Article
Use of a Comprehensive 66‐Gene Cholestasis Sequencing Panel in 2171 Cholestatic Infants, Children, and Young Adults
Karpen, Saul J., Kamath, Binita M., Alexander, John J., Ichetovkin, Ilia, Rosenthal, Philip, Sokol, Ronald J., Dunn, Shelley, Thompson, Richard J., Heubi, James E.
Published in Journal of pediatric gastroenterology and nutrition (01.05.2021)
Published in Journal of pediatric gastroenterology and nutrition (01.05.2021)
Get full text
Journal Article
Long‐term medical management of the pediatric patient after liver transplantation: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation
Kelly, Deirdre A., Bucuvalas, John C., Alonso, Estella M., Karpen, Saul J., Allen, Upton, Green, Michael, Farmer, Douglas, Shemesh, Eyal, McDonald, Ruth A.
Published in Liver transplantation (01.08.2013)
Published in Liver transplantation (01.08.2013)
Get full text
Journal Article
TGR5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure‐induced stress in mice
Eblimit, Zeena, Thevananther, Sundararajah, Karpen, Saul J., Taegtmeyer, Heinrich, Moore, David D., Adorini, Luciano, Penny, Daniel J., Desai, Moreshwar S.
Published in Cardiovascular therapeutics (01.10.2018)
Published in Cardiovascular therapeutics (01.10.2018)
Get full text
Journal Article
Pattern of Diagnostic Evaluation for the Causes of Pediatric Acute Liver Failure: An Opportunity for Quality Improvement
Narkewicz, Michael R., MD, Dell Olio, Dominic, MD, Karpen, Saul J., MD, PhD, Murray, Karen F., MD, Schwarz, Kathy, MD, Yazigi, Nada, MD, Zhang, Song, MS, Belle, Steven H., PhD, MScHyg, Squires, Robert H., MD
Published in The Journal of pediatrics (01.12.2009)
Published in The Journal of pediatrics (01.12.2009)
Get full text
Journal Article
Loss of zebrafish pkd1l1 causes biliary defects that have implications for biliary atresia splenic malformation
Ali, Rouknuddin Q, Meyer-Miner, Anne, David-Rachel, Marie, Lee, Fiona J H, Wilkins, Benjamin J, Karpen, Saul J, Ciruna, Brian, Ghanekar, Anand, Kamath, Binita M
Published in Disease models & mechanisms (01.10.2023)
Published in Disease models & mechanisms (01.10.2023)
Get full text
Journal Article
Hypertrophic cardiomyopathy and dysregulation of cardiac energetics in a mouse model of biliary fibrosis
Desai, Moreshwar S., Shabier, Zainuer, Taylor, Michael, Lam, Fong, Thevananther, Sundararajah, Kosters, Astrid, Karpen, Saul J.
Published in Hepatology (Baltimore, Md.) (01.06.2010)
Published in Hepatology (Baltimore, Md.) (01.06.2010)
Get full text
Journal Article
Treatment of Neonatal Hemochromatosis with Exchange Transfusion and Intravenous Immunoglobulin
Rand, Elizabeth B., MD, Karpen, Saul J., MD, PhD, Kelly, Susan, RN, Mack, Cara L., MD, Malatack, J. Jeffrey, MD, Sokol, Ronald J., MD, Whitington, Peter F., MD
Published in The Journal of pediatrics (01.10.2009)
Published in The Journal of pediatrics (01.10.2009)
Get full text
Journal Article
Medical Status of 219 Children with Biliary Atresia Surviving Long-Term with Their Native Livers: Results from a North American Multicenter Consortium
Ng, Vicky Lee, MD, Haber, Barbara H., MD, Magee, John C., MD, Miethke, Alexander, MD, Murray, Karen F., MD, Michail, Sonia, MD, Karpen, Saul J., MD, Kerkar, Nanda, MD, Molleston, Jean P., MD, Romero, Rene, MD, Rosenthal, Philip, MD, Schwarz, Kathleen B., MD, Shneider, Benjamin L., MD, Turmelle, Yumirle P., MD, Alonso, Estella M., MD, Sherker, Averell H., MD, Sokol, Ronald J., MD
Published in The Journal of pediatrics (01.09.2014)
Published in The Journal of pediatrics (01.09.2014)
Get full text
Journal Article
Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study
Kamath, Binita M., Ye, Wen, Goodrich, Nathan P., Loomes, Kathleen M., Romero, Rene, Heubi, James E., Leung, Daniel H., Spinner, Nancy B., Piccoli, David A., Alonso, Estella M., Guthery, Stephen L., Karpen, Saul J., Mack, Cara L., Molleston, Jean P., Murray, Karen F., Rosenthal, Philip, Squires, James E., Teckman, Jeffrey, Wang, Kasper S., Thompson, Richard, Magee, John C., Sokol, Ronald J.
Published in Hepatology communications (01.03.2020)
Published in Hepatology communications (01.03.2020)
Get full text
Journal Article
Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome
Shneider, Benjamin L., Spino, Cathie, Kamath, Binita M., Magee, John C., Bass, Lee M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Murray, Karen F., Loomes, Kathleen M., Rosenthal, Philip, Karpen, Saul J., Leung, Daniel H., Guthery, Stephen L., Thomas, Danny, Sherker, Averell H., Sokol, Ronald J.
Published in Hepatology communications (01.10.2018)
Published in Hepatology communications (01.10.2018)
Get full text
Journal Article