New perspectives for targeting RAF kinase in human cancer
Karoulia, Zoi, Gavathiotis, Evripidis, Poulikakos, Poulikos I.
Published in Nature reviews. Cancer (01.11.2017)
Published in Nature reviews. Cancer (01.11.2017)
Get full text
Journal Article
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors
Ahmed, Tamer A., Adamopoulos, Christos, Karoulia, Zoi, Wu, Xuewei, Sachidanandam, Ravi, Aaronson, Stuart A., Poulikakos, Poulikos I.
Published in Cell reports (Cambridge) (02.01.2019)
Published in Cell reports (Cambridge) (02.01.2019)
Get full text
Journal Article
An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling
Karoulia, Zoi, Wu, Yang, Ahmed, Tamer A., Xin, Qisheng, Bollard, Julien, Krepler, Clemens, Wu, Xuewei, Zhang, Chao, Bollag, Gideon, Herlyn, Meenhard, Fagin, James A., Lujambio, Amaia, Gavathiotis, Evripidis, Poulikakos, Poulikos I.
Published in Cancer cell (12.09.2016)
Published in Cancer cell (12.09.2016)
Get full text
Journal Article
RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions
Hogstad, Brandon, Berres, Marie-Luise, Chakraborty, Rikhia, Tang, Jun, Bigenwald, Camille, Serasinghe, Madhavika, Lim, Karen Phaik Har, Lin, Howard, Man, Tsz-Kwong, Remark, Romain, Baxter, Samantha, Kana, Veronika, Jordan, Stefan, Karoulia, Zoi, Kwan, Wing-Hong, Leboeuf, Marylene, Brandt, Elisa, Salmon, Helene, McClain, Kenneth, Poulikakos, Poulikos, Chipuk, Jerry, Mulder, Willem J M, Allen, Carl E, Merad, Miriam
Published in The Journal of experimental medicine (02.01.2018)
Published in The Journal of experimental medicine (02.01.2018)
Get full text
Journal Article
BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology
Bigenwald, Camille, Le Berichel, Jessica, Wilk, C. Matthias, Chakraborty, Rikhia, Chen, Steven T., Tabachnikova, Alexandra, Mancusi, Rebecca, Abhyankar, Harshal, Casanova-Acebes, Maria, Laface, Ilaria, Akturk, Guray, Jobson, Jenielle, Karoulia, Zoi, Martin, Jerome C., Grout, John, Rafiei, Anahita, Lin, Howard, Manz, Markus G., Baccarini, Alessia, Poulikakos, Poulikos I., Brown, Brian D., Gnjatic, Sacha, Lujambio, Amaia, McClain, Kenneth L., Picarsic, Jennifer, Allen, Carl E., Merad, Miriam
Published in Nature medicine (01.05.2021)
Published in Nature medicine (01.05.2021)
Get full text
Journal Article
The Phosphatase-Transcription Activator EYA1 Is Targeted by Anaphase-Promoting Complex/Cdh1 for Degradation at M-to-G1 Transition
Sun, Jianbo, Karoulia, Zoi, Wong, Elaine Y. M., Ahmed, Mohi, Itoh, Keiji, Xu, Pin-Xian
Published in Molecular and Cellular Biology (01.03.2013)
Published in Molecular and Cellular Biology (01.03.2013)
Get full text
Journal Article
Studies on the essential intramolecular interaction between the A1 and A2 domains of von Willebrand factor
Karoulia, Zoi, Papadopoulos, Georgios, Nomikos, Michail, Thanassoulas, Angelos, Papadopoulou, Theodora Choli, Nounesis, George, Kontou, Maria, Stathopoulos, Constantinos, Leonidas, Demetres D
Published in Protein and peptide letters (01.02.2013)
Published in Protein and peptide letters (01.02.2013)
Get more information
Journal Article
Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling
Adamopoulos, Christos, Ahmed, Tamer A, Tucker, Maxwell R, Ung, Peter M U, Xiao, Min, Karoulia, Zoi, Amabile, Angelo, Wu, Xuewei, Aaronson, Stuart A, Ang, Celina, Rebecca, Vito W, Brown, Brian D, Schlessinger, Avner, Herlyn, Meenhard, Wang, Qi, Shaw, David E, Poulikakos, Poulikos I
Published in Cancer discovery (01.07.2021)
Published in Cancer discovery (01.07.2021)
Get full text
Journal Article
Abstract LB-119: SHP2 drives adaptive resistance to ERK signaling inhibition in molecularly defined subsets of ERK-dependent tumors
Adamopoulos, Christos, Ahmed, Tamer A., Karoulia, Zoi, Wu, Xuewei, Sachidanandam, Ravi, Aaronson, Stuart A., Poulikakos, Poulikos I.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract 41: Tumor resistance to CDK4/6 inhibitors and degraders determined by the expression state of CDK6
Wu, Xuewei, Yang, Xiaobao, Xiong, Yan, Li, Ruitong, Ito, Takahiro, Ahmed, Tamer, Karoulia, Zoi, Adamopoulos, Christos, Wang, Hong, Wang, Li, Xie, Ling, Ueberheide, Beatrix, Aaronson, Stuart, Chen, Xian, Sellers, William, Buchanan, Sean, Jin, Jian, Poulikakos, Poulikos I.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
Abstract 78: A strategy for effective targeting of oncogenic BRAF signaling with increased therapeutic index using conformation-selective RAF and MEK inhibitors
Adamopoulos, Christos, Ahmed, Tamer A., Tucker, Maxwell R., Ung, Peter M., Xiao, Min, Karoulia, Zoi, Wu, Xuewei, Aaronson, Stuart A., Ang, Celina, Rebecca, Vito, Schlessinger, Avner, Herlyn, Meenhard, Wang, Qi, Shaw, David E., Poulikakos, Poulikos I.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling
Karoulia, Zoi, Wu, Yang, Ahmed, Tamer A., Xin, Qisheng, Bollard, Julien, Krepler, Clemens, Wu, Xuewei, Zhang, Chao, Bollag, Gideon, Herlyn, Meenhard, Fagin, James A., Lujambio, Amaia, Gavathiotis, Evripidis, Poulikakos, Poulikos I.
Published in Cancer cell (12.09.2016)
Published in Cancer cell (12.09.2016)
Get full text
Journal Article
Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders
Wu, Xuewei, Yang, Xiaobao, Xiong, Yan, Li, Ruitong, Ito, Takahiro, Ahmed, Tamer A, Karoulia, Zoi, Adamopoulos, Christos, Wang, Hong, Wang, Li, Xie, Ling, Liu, Jing, Ueberheide, Beatrix, Aaronson, Stuart A, Chen, Xian, Buchanan, Sean G, Sellers, William R, Jin, Jian, Poulikakos, Poulikos I
Published in Nature cancer (01.04.2021)
Published in Nature cancer (01.04.2021)
Get more information
Journal Article
Abstract 1225: A unified model of RAF inhibitor action determines inhibitor activity in BRAF-dependent tumors
Karoulia, Zoi, Wu, Yang, Ahmed, Tamer A., Xin, Qisheng, Bollard, Julien, Krepler, Clemens, Wu, Xuewei, Zhang, Chao, Bollag, Gideon, Herlyn, Meenhard, Fagin, James A., Lujambio, Amaia, Gavathiotis, Evripidis, Poulikakos, Poulikos I.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
BRAF V600E -induced senescence drives Langerhans cell histiocytosis pathophysiology
Bigenwald, Camille, Le Berichel, Jessica, Wilk, C Matthias, Chakraborty, Rikhia, Chen, Steven T, Tabachnikova, Alexandra, Mancusi, Rebecca, Abhyankar, Harshal, Casanova-Acebes, Maria, Laface, Ilaria, Akturk, Guray, Jobson, Jenielle, Karoulia, Zoi, Martin, Jerome C, Grout, John, Rafiei, Anahita, Lin, Howard, Manz, Markus G, Baccarini, Alessia, Poulikakos, Poulikos I, Brown, Brian D, Gnjatic, Sacha, Lujambio, Amaia, McClain, Kenneth L, Picarsic, Jennifer, Allen, Carl E, Merad, Miriam
Published in Nature medicine (01.05.2021)
Get full text
Published in Nature medicine (01.05.2021)
Journal Article
The Phosphatase-Transcription Activator EYA1 Is Targeted by Anaphase-Promoting Complex/Cdh1 for Degradation at M-to-G 1 Transition
Sun, Jianbo, Karoulia, Zoi, Wong, Elaine Y. M., Ahmed, Mohi, Itoh, Keiji, Xu, Pin-Xian
Published in Molecular and cellular biology (01.03.2013)
Published in Molecular and cellular biology (01.03.2013)
Get full text
Journal Article
Compositions and methods for treating CDK4/6-mediated cancer
Jin, Jian, Liu, Jing, Xiong, Yan, Poulikakos, Poulikos, Yang, Xiaobao, Wu, Xuewei, Karoulia, Zoi, Ahmed, Tamer
Year of Publication 03.01.2023
Get full text
Year of Publication 03.01.2023
Patent
COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER
Jin, Jian, Liu, Jing, Xiong, Yan, Poulikakos, Poulikos, Yang, Xiaobao, Wu, Xuewei, Karoulia, Zoi, Ahmed, Tamer
Year of Publication 24.02.2022
Get full text
Year of Publication 24.02.2022
Patent
IL1RAP ANTIBODIES AND USES THEREOF
DOYLE, Patrick James, CHEN, Jiahao, NAKAYAMA, Yasumi, BUGAJ-GAWEDA, Bozena, BENARD, Lumie Marie Josephine, GUERNAH, Ilhem, ROOPNARIANE, Adriana Permaul, KAROULIA, Zoi, CARPENITO, Carmine, BIDERMAN, Lynn, LIPPINCOTT, John Andrew, DUEY, Dana Yen Mei, LORENZ, Ivo C
Year of Publication 02.10.2024
Get full text
Year of Publication 02.10.2024
Patent