Seipin regulates ER-lipid droplet contacts and cargo delivery
Salo, Veijo T, Belevich, Ilya, Li, Shiqian, Karhinen, Leena, Vihinen, Helena, Vigouroux, Corinne, Magré, Jocelyne, Thiele, Christoph, Hölttä-Vuori, Maarit, Jokitalo, Eija, Ikonen, Elina
Published in The EMBO journal (15.12.2016)
Published in The EMBO journal (15.12.2016)
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Journal Article
Target inhibition networks: predicting selective combinations of druggable targets to block cancer survival pathways
Tang, Jing, Karhinen, Leena, Xu, Tao, Szwajda, Agnieszka, Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero
Published in PLoS computational biology (01.09.2013)
Published in PLoS computational biology (01.09.2013)
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Journal Article
Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage
Pfisterer, Simon G., Gateva, Gergana, Horvath, Peter, Pirhonen, Juho, Salo, Veijo T., Karhinen, Leena, Varjosalo, Markku, Ryhänen, Samppa J., Lappalainen, Pekka, Ikonen, Elina
Published in Nature communications (31.03.2017)
Published in Nature communications (31.03.2017)
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Journal Article
Gene expression in the dorsal root ganglion and the cerebrospinal fluid metabolome in polyneuropathy and opioid tolerance in rats
Ahlström, Fredrik H.G., Viisanen, Hanna, Karhinen, Leena, Velagapudi, Vidya, Blomqvist, Kim J., Lilius, Tuomas O., Rauhala, Pekka V., Kalso, Eija A.
Published in IBRO neuroscience reports (01.12.2024)
Published in IBRO neuroscience reports (01.12.2024)
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Journal Article
Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells
Gautam, Prson, Karhinen, Leena, Szwajda, Agnieszka, Jha, Sawan Kumar, Yadav, Bhagwan, Aittokallio, Tero, Wennerberg, Krister
Published in Molecular cancer (10.05.2016)
Published in Molecular cancer (10.05.2016)
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Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes
Combot, Yoann, Salo, Veijo T., Chadeuf, Gilliane, Hölttä, Maarit, Ven, Katharina, Pulli, Ilari, Ducheix, Simon, Pecqueur, Claire, Renoult, Ophélie, Lak, Behnam, Li, Shiqian, Karhinen, Leena, Belevich, Ilya, Le May, Cedric, Rieusset, Jennifer, Le Lay, Soazig, Croyal, Mikael, Tayeb, Karim Si, Vihinen, Helena, Jokitalo, Eija, Törnquist, Kid, Vigouroux, Corinne, Cariou, Bertrand, Magré, Jocelyne, Larhlimi, Abdelhalim, Ikonen, Elina, Prieur, Xavier
Published in Cell reports (Cambridge) (11.01.2022)
Published in Cell reports (Cambridge) (11.01.2022)
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OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism
Kentala, Henriikka, Koponen, Annika, Vihinen, Helena, Pirhonen, Juho, Liebisch, Gerhard, Pataj, Zoltan, Kivelä, Annukka, Li, Shiqian, Karhinen, Leena, Jääskeläinen, Eeva, Andrews, Robert, Meriläinen, Leena, Matysik, Silke, Ikonen, Elina, Zhou, You, Jokitalo, Eija, Olkkonen, Vesa M.
Published in Cellular and molecular life sciences : CMLS (01.11.2018)
Published in Cellular and molecular life sciences : CMLS (01.11.2018)
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The effects of chronic high-dose morphine on microgliosis and the microglial transcriptome in rat spinal cord
Ahlström, Fredrik HG, Viisanen, Hanna, Karhinen, Leena, Mätlik, Kert, Blomqvist, Kim J, Lilius, Tuomas O, Sidorova, Yulia A, Palada, Vinko, Rauhala, Pekka V, Kalso, Eija A
Published in Molecular pain (01.01.2023)
Published in Molecular pain (01.01.2023)
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Abstract B21: Enhanced understanding of drug responses and drug-drug interactions in triple negative breast cancer cells with a multiplexed cell viability and cell death readout
Gautam, Prson, Karhinen, Leena, Szwajda, Agnieszka, Jha, Sawan Kumar, Yadav, Bhagwan, Aittokallio, Tero, Wennerberg, Krister
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Abstract P6-02-01: Identification of subgroups of triple negative breast cancer cells with selective responses to mTOR, CDK, mitotic and proteasome inhibitors
Gautam, Prson, Karhinen, Leena, Szwajda, Agnieszka, Jha, Sawan Kumar, Yadav, Bhagwan, Aittokallio, Tero, Wennerberg, Krister
Published in Cancer research (Chicago, Ill.) (01.05.2015)
Published in Cancer research (Chicago, Ill.) (01.05.2015)
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Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways: e1003226
Tang, Jing, Karhinen, Leena, Xu, Tao, Szwajda, Agnieszka, Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero
Published in PLoS computational biology (01.09.2013)
Published in PLoS computational biology (01.09.2013)
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Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles
Szwajda, Agnieszka, Gautam, Prson, Karhinen, Leena, Jha, Sawan Kumar, Saarela, Jani, Shakyawar, Sushil, Turunen, Laura, Yadav, Bhagwan, Tang, Jing, Wennerberg, Krister, Aittokallio, Tero
Published in Chemistry & biology (20.08.2015)
Published in Chemistry & biology (20.08.2015)
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