Intravenous BCG Vaccination of Diversity Outbred Mice Results in Moderately Enhanced Protection against Challenge with Mycobacterium tuberculosis Compared to Intradermal Vaccination
Kurtz, Sherry L, Mittereder, Lara R, Lehman, Chelsea C, Khan, Hamda, Gould, Victoria A, Elkins, Karen L
Published in Infection and immunity (18.07.2023)
Published in Infection and immunity (18.07.2023)
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Deficiency in CCR2 increases susceptibility of mice to infection with an intracellular pathogen, Francisella tularensis LVS, but does not impair development of protective immunity
Kurtz, Sherry L, De Pascalis, Roberto, Meierovics, Anda I, Elkins, Karen L
Published in PloS one (24.03.2021)
Published in PloS one (24.03.2021)
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In vivo and in vitro immune responses against Francisella tularensis vaccines are comparable among Fischer 344 rat substrains
De Pascalis, Roberto, Bhargava, Varunika, Espich, Scott, Wu, Terry H, Gelhaus, H Carl, Elkins, Karen L
Published in Frontiers in microbiology (13.07.2023)
Published in Frontiers in microbiology (13.07.2023)
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Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice
Kurtz, Sherry L, Baker, Richard E, Boehm, Frederick J, Lehman, Chelsea C, Mittereder, Lara R, Khan, Hamda, Rossi, Amy P, Gatti, Daniel M, Beamer, Gillian, Sassetti, Christopher M, Elkins, Karen L
Published in PLoS pathogens (01.03.2024)
Published in PLoS pathogens (01.03.2024)
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Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice
Gatti, Daniel M, Tyler, Anna L, Mahoney, J Matthew, Churchill, Gary A, Yener, Bulent, Koyuncu, Deniz, Gurcan, Metin N, Niazi, Mk Khalid, Tavolara, Thomas, Gower, Adam, Dayao, Denise, McGlone, Emily, Ginese, Melanie L, Specht, Aubrey, Alsharaydeh, Anas, Tessier, Philipe A, Kurtz, Sherry L, Elkins, Karen L, Kramnik, Igor, Beamer, Gillian
Published in PLoS pathogens (01.06.2024)
Published in PLoS pathogens (01.06.2024)
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Journal Article
A panel of correlates predicts vaccine-induced protection of rats against respiratory challenge with virulent Francisella tularensis
De Pascalis, Roberto, Hahn, Andrew, Brook, Helen M, Ryden, Patrik, Donart, Nathaniel, Mittereder, Lara, Frey, Blake, Wu, Terry H, Elkins, Karen L
Published in PloS one (25.05.2018)
Published in PloS one (25.05.2018)
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Production of IFN-γ by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9
De Pascalis, Roberto, Rossi, Amy P., Mittereder, Lara, Takeda, Kazuyo, Akue, Adovi, Kurtz, Sherry L., Elkins, Karen L.
Published in PloS one (03.08.2020)
Published in PloS one (03.08.2020)
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Journal Article
Innate and Adaptive Immunity to Francisella
ELKINS, KAREN L., COWLEY, SIOBHÁN C., BOSIO, CATHARINE M.
Published in Annals of the New York Academy of Sciences (01.06.2007)
Published in Annals of the New York Academy of Sciences (01.06.2007)
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The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection
Kurtz, Sherry L, Rossi, Amy P, Beamer, Gillian L, Gatti, Dan M, Kramnik, Igor, Elkins, Karen L
Published in mSphere (15.04.2020)
Published in mSphere (15.04.2020)
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Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge
Cole, Leah E, Yang, Yang, Elkins, Karen L, Fernandez, Ellen T, Qureshi, Nilofer, Shlomchik, Mark J, Herzenberg, Leonard A, Herzenberg, Leonore A, Vogel, Stefanie N
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
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IL-12Rβ2 is critical for survival of primary Francisella tularensis LVS infection
Melillo, Amanda A., Foreman, Oded, Elkins, Karen L.
Published in Journal of leukocyte biology (01.05.2013)
Published in Journal of leukocyte biology (01.05.2013)
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Epicutaneous Model of Community-Acquired Staphylococcus aureus Skin Infections
Prabhakara, Ranjani, Foreman, Oded, De Pascalis, Roberto, Lee, Gloria M, Plaut, Roger D, Kim, Stanley Y, Stibitz, Scott, Elkins, Karen L, Merkel, Tod J
Published in Infection and Immunity (01.04.2013)
Published in Infection and Immunity (01.04.2013)
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Development of functional and molecular correlates of vaccine-induced protection for a model intracellular pathogen, F. tularensis LVS
De Pascalis, Roberto, Chou, Alicia Y, Bosio, Catharine M, Huang, Chiung-Yu, Follmann, Dean A, Elkins, Karen L
Published in PLoS pathogens (01.01.2012)
Published in PLoS pathogens (01.01.2012)
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Journal Article
A Francisella tularensis Pathogenicity Island Required for Intramacrophage Growth
NANO, Francis E, NA ZHANG, ELKINS, Karen L, COWLEY, Siobhan C, KLOSE, Karl E, CHEUNG, Karen K. M, ROBERTS, Michael J, LUDU, Jagjit S, LETENDRE, Gregg W, MEIEROVICS, Anda I, STEPHENS, Gwen
Published in Journal of Bacteriology (01.10.2004)
Published in Journal of Bacteriology (01.10.2004)
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Working correlates of protection predict SchuS4-derived-vaccine candidates with improved efficacy against an intracellular bacterium, Francisella tularensis
De Pascalis, Roberto, Frey, Blake, Rice, Helen M., Bhargava, Varunika, Wu, Terry H., Peterson, Ross L., Conlan, J. Wayne, Sjöstedt, Anders, Elkins, Karen L.
Published in npj vaccines (17.08.2022)
Published in npj vaccines (17.08.2022)
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The Francisella Pathogenicity Island Protein PdpD Is Required for Full Virulence and Associates with Homologues of the Type VI Secretion System
LUDU, Jagjit S, DE BRUIN, Olle M, DUPLANTIS, Barry N, SCHMERK, Crystal L, CHOU, Alicia Y, ELKINS, Karen L, NANO, Francis E
Published in Journal of Bacteriology (01.07.2008)
Published in Journal of Bacteriology (01.07.2008)
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