Pore-modulating toxins exploit inherent slow inactivation to block K⁺ channels
Karbat, Izhar, Altman-Gueta, Hagit, Fine, Shachar, Szanto, Tibor, Hamer-Rogotner, Shelly, Dym, Orly, Frolow, Felix, Gordon, Dalia, Panyi, Gyorgy, Gurevitz, Michael, Reuveny, Eitan
Published in Proceedings of the National Academy of Sciences - PNAS (10.09.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (10.09.2019)
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Journal Article
Non‐sedating antihistamines block G‐protein‐gated inwardly rectifying K+ channels
Chen, I‐Shan, Liu, Chang, Tateyama, Michihiro, Karbat, Izhar, Uesugi, Motonari, Reuveny, Eitan, Kubo, Yoshihiro
Published in British journal of pharmacology (01.09.2019)
Published in British journal of pharmacology (01.09.2019)
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Journal Article
Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na+ channels
Moran, Yehu, Kahn, Roy, Cohen, Lior, Gur, Maya, Karbat, Izhar, Gordon, Dalia, Gurevitz, Michael
Published in Biochemical journal (15.08.2007)
Published in Biochemical journal (15.08.2007)
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Journal Article
X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity
Karbat, Izhar, Turkov, Michael, Cohen, Lior, Kahn, Roy, Gordon, Dalia, Gurevitz, Michael, Frolow, Felix
Published in Journal of molecular biology (16.02.2007)
Published in Journal of molecular biology (16.02.2007)
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Journal Article
Direct Evidence That Receptor Site-4 of Sodium Channel Gating Modifiers Is Not Dipped in the Phospholipid Bilayer of Neuronal Membranes
Cohen, Lior, Gilles, Nicolas, Karbat, Izhar, Ilan, Nitza, Gordon, Dalia, Gurevitz, Michael
Published in The Journal of biological chemistry (28.07.2006)
Published in The Journal of biological chemistry (28.07.2006)
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Journal Article
Deletion of PsbM in Tobacco Alters the QB Site Properties and the Electron Flow within Photosystem II
Umate, Pavan, Schwenkert, Serena, Karbat, Izhar, Bosco, Cristina Dal, Mlcòchová, Lada, Volz, Stefanie, Zer, Hagit, Herrmann, Reinhold G., Ohad, Itzhak, Meurer, Jörg
Published in The Journal of biological chemistry (30.03.2007)
Published in The Journal of biological chemistry (30.03.2007)
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Journal Article
Expression and Mutagenesis of the Sea Anemone Toxin Av2 Reveals Key Amino Acid Residues Important for Activity on Voltage-Gated Sodium Channels
Moran, Yehu, Cohen, Lior, Kahn, Roy, Karbat, Izhar, Gordon, Dalia, Gurevitz, Michael
Published in Biochemistry (Easton) (25.07.2006)
Published in Biochemistry (Easton) (25.07.2006)
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Journal Article
Conversion of a scorpion toxin agonist into an antagonist highlights an acidic residue involved in voltage sensor trapping during activation of neuronal Na+ channels
Karbat, Izhar, Cohen, Lior, Gilles, Nicholas, Gordon, Dalia, Gurevitz, Michael, Izhar, Karbat, Lior, Cohen, Nicholas, Gilles, Dalia, Gordon, Michael, Gurevitz
Published in The FASEB journal (01.04.2004)
Published in The FASEB journal (01.04.2004)
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Journal Article
A Molecular Lid Mechanism of K+ Channel Blocker Action Revealed by a Cone Peptide
Saikia, Chandamita, Dym, Orly, Altman-Gueta, Hagit, Gordon, Dalia, Reuveny, Eitan, Karbat, Izhar
Published in Journal of molecular biology (20.08.2021)
Published in Journal of molecular biology (20.08.2021)
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Journal Article
Reduced activity of GIRK1‐containing heterotetramers is sufficient to affect neuronal functions, including synaptic plasticity and spatial learning and memory
Mett, Alice, Karbat, Izhar, Tsoory, Michael, Fine, Shachar, Iwanir, Shachar, Reuveny, Eitan
Published in The Journal of physiology (01.01.2021)
Published in The Journal of physiology (01.01.2021)
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Journal Article
Hetromerization of Kir Channels: Principles of Assembly and Physiological Significance
Mett, Alice, Fine, Shachar, Kollewe, Astrid, Karbat, Izhar, Fakler, Bernd, Reuveny, Eitan
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Inhibitory Mechanisms of G-protein-gated Inwardly Rectifying K+ Channel by Antihistamines
Chen, I-Shan, Liu, Chang, Tateyama, Michihiro, Karbat, Izhar, Uesugi, Motonari, Reuveny, Eitan, Kubo, Yoshihiro
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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