Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy
Lee, Jaecheol, Termglinchan, Vittavat, Diecke, Sebastian, Itzhaki, Ilanit, Lam, Chi Keung, Garg, Priyanka, Lau, Edward, Greenhaw, Matthew, Seeger, Timon, Wu, Haodi, Zhang, Joe Z., Chen, Xingqi, Gil, Isaac Perea, Ameen, Mohamed, Sallam, Karim, Rhee, June-Wha, Churko, Jared M., Chaudhary, Rinkal, Chour, Tony, Wang, Paul J., Snyder, Michael P., Chang, Howard Y., Karakikes, Ioannis, Wu, Joseph C.
Published in Nature (London) (01.08.2019)
Published in Nature (London) (01.08.2019)
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Journal Article
A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay
Seeger, Timon, Shrestha, Rajani, Lam, Chi Keung, Chen, Caressa, McKeithan, Wesley L, Lau, Edward, Wnorowski, Alexa, McMullen, George, Greenhaw, Matthew, Lee, Jaecheol, Oikonomopoulos, Angelos, Lee, Soah, Yang, Huaxiao, Mercola, Mark, Wheeler, Matthew, Ashley, Euan A, Yang, Fan, Karakikes, Ioannis, Wu, Joseph C
Published in Circulation (New York, N.Y.) (05.02.2019)
Published in Circulation (New York, N.Y.) (05.02.2019)
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Journal Article
Precision unleashed: tackling DNA mismatch repair for enhanced prime editing
Ramchandani, Rohin, Bharucha, Nike, Karakikes, Ioannis
Published in Molecular therapy. Nucleic acids (12.12.2023)
Published in Molecular therapy. Nucleic acids (12.12.2023)
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Journal Article
Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling
Abilez, Oscar J., Tzatzalos, Evangeline, Yang, Huaxiao, Zhao, Ming‐Tao, Jung, Gwanghyun, Zöllner, Alexander M., Tiburcy, Malte, Riegler, Johannes, Matsa, Elena, Shukla, Praveen, Zhuge, Yan, Chour, Tony, Chen, Vincent C., Burridge, Paul W., Karakikes, Ioannis, Kuhl, Ellen, Bernstein, Daniel, Couture, Larry A., Gold, Joseph D., Zimmermann, Wolfram H., Wu, Joseph C.
Published in Stem cells (Dayton, Ohio) (01.02.2018)
Published in Stem cells (Dayton, Ohio) (01.02.2018)
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Journal Article
A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell–Based Models for Cardiovascular Diseases
Karakikes, Ioannis, Termglinchan, Vittavat, Cepeda, Diana A, Lee, Jaecheol, Diecke, Sebastian, Hendel, Ayal, Itzhaki, Ilanit, Ameen, Mohamed, Shrestha, Rajani, Wu, Haodi, Ma, Ning, Shao, Ning-Yi, Seeger, Timon, Woo, Nicole, Wilson, Kitchener D, Matsa, Elena, Porteus, Matthew H, Sebastiano, Vittorio, Wu, Joseph C
Published in Circulation research (12.05.2017)
Published in Circulation research (12.05.2017)
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Journal Article
Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro
Matsa, Elena, Burridge, Paul W., Yu, Kun-Hsing, Ahrens, John H., Termglinchan, Vittavat, Wu, Haodi, Liu, Chun, Shukla, Praveen, Sayed, Nazish, Churko, Jared M., Shao, Ningyi, Woo, Nicole A., Chao, Alexander S., Gold, Joseph D., Karakikes, Ioannis, Snyder, Michael P., Wu, Joseph C.
Published in Cell stem cell (01.09.2016)
Published in Cell stem cell (01.09.2016)
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Journal Article
Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells
Stillitano, Francesca, Hansen, Jens, Kong, Chi-Wing, Karakikes, Ioannis, Funck-Brentano, Christian, Geng, Lin, Scott, Stuart, Reynier, Stephan, Wu, Ma, Valogne, Yannick, Desseaux, Carole, Salem, Joe-Elie, Jeziorowska, Dorota, Zahr, Noël, Li, Ronald, Iyengar, Ravi, Hajjar, Roger J, Hulot, Jean-Sébastien
Published in eLife (30.01.2017)
Published in eLife (30.01.2017)
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Journal Article
Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy
Feyen, Dries A M, Perea-Gil, Isaac, Maas, Renee G C, Harakalova, Magdalena, Gavidia, Alexandra A, Arthur Ataam, Jennifer, Wu, Ting-Hsuan, Vink, Aryan, Pei, Jiayi, Vadgama, Nirmal, Suurmeijer, Albert J, Te Rijdt, Wouter P, Vu, Michelle, Amatya, Prashila L, Prado, Maricela, Zhang, Yuan, Dunkenberger, Logan, Sluijter, Joost P G, Sallam, Karim, Asselbergs, Folkert W, Mercola, Mark, Karakikes, Ioannis
Published in Circulation (New York, N.Y.) (03.08.2021)
Published in Circulation (New York, N.Y.) (03.08.2021)
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Journal Article
Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs
Zhao, Ming-Tao, Chen, Haodong, Liu, Qing, Shao, Ning-Yi, Sayed, Nazish, Wo, Hung-Ta, Zhang, Joe Z., Ong, Sang-Ging, Liu, Chun, Kim, Youngkyun, Yang, Huaxiao, Chour, Tony, Ma, Hong, Gutierrez, Nuria Marti, Karakikes, Ioannis, Mitalipov, Shoukhrat, Snyder, Michael P., Wu, Joseph C.
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2017)
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Journal Article
Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium
Turnbull, Irene C, Karakikes, Ioannis, Serrao, Gregory W, Backeris, Peter, Lee, Jia-Jye, Xie, Chaoqin, Senyei, Grant, Gordon, Ronald E, Li, Ronald A, Akar, Fadi G, Hajjar, Roger J, Hulot, Jean-Sébastien, Costa, Kevin D
Published in The FASEB journal (01.02.2014)
Published in The FASEB journal (01.02.2014)
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Journal Article
A Novel Recessive Mutation in SPEG Causes Early Onset Dilated Cardiomyopathy
Levitas, Aviva, Muhammad, Emad, Zhang, Yuan, Perea Gil, Isaac, Serrano, Ricardo, Diaz, Nashielli, Arafat, Maram, Gavidia, Alexandra A, Kapiloff, Michael S, Mercola, Mark, Etzion, Yoram, Parvari, Ruti, Karakikes, Ioannis
Published in PLoS genetics (14.09.2020)
Published in PLoS genetics (14.09.2020)
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Journal Article
iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy
Briganti, Francesca, Sun, Han, Wei, Wu, Wu, Jingyan, Zhu, Chenchen, Liss, Martin, Karakikes, Ioannis, Rego, Shannon, Cipriano, Andrea, Snyder, Michael, Meder, Benjamin, Xu, Zhenyu, Millat, Gilles, Gotthardt, Michael, Mercola, Mark, Steinmetz, Lars M.
Published in Cell reports (Cambridge) (08.09.2020)
Published in Cell reports (Cambridge) (08.09.2020)
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Journal Article
AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes
Bruyneel, Arne A N, Colas, Alexandre R, Karakikes, Ioannis, Mercola, Mark
Published in PloS one (26.12.2019)
Published in PloS one (26.12.2019)
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Journal Article
Generation of human induced pluripotent stem cell lines derived from four patients with a pathogenic ALPK3 variant associated with adult-onset hypertrophic cardiomyopathy (HCM)
Cheawsamoot, Chanatjit, Ramchandani, Rohin, Ameen, Mohamed, Arthur, Jennifer Ataam, Khongphatthanayothin, Apichai, Shotelersuk, Vorasuk, Karakikes, Ioannis
Published in Stem cell research (01.12.2023)
Published in Stem cell research (01.12.2023)
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Journal Article
Corrigendum to “Generation of human induced pluripotent stem cell lines derived from four patients with a pathogenic ALPK3 variant associated with adult-onset hypertrophic cardiomyopathy (HCM)” [Stem Cell Res. 73 (2023) 103233]
Cheawsamoot, Chanatjit, Ramchandani, Rohin, Ameen, Mohamed, Arthur, Jennifer Ataam, Khongphatthanayothin, Apichai, Karakikes, Ioannis, Shotelersuk, Vorasuk
Published in Stem cell research (01.02.2024)
Published in Stem cell research (01.02.2024)
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Journal Article
Treatment of volumetric muscle loss in mice using nanofibrillar scaffolds enhances vascular organization and integration
Nakayama, Karina H., Quarta, Marco, Paine, Patrick, Alcazar, Cynthia, Karakikes, Ioannis, Garcia, Victor, Abilez, Oscar J., Calvo, Nicholas S., Simmons, Chelsey S., Rando, Thomas A., Huang, Ngan F.
Published in Communications biology (07.05.2019)
Published in Communications biology (07.05.2019)
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Journal Article
Adapting to the future: examining the impact of transport automation and digitalization on the labor force through the perspectives of stakeholders in all transport sectors
Polydoropoulou, Amalia, Thanopoulou, Helen, Karakikes, Ioannis, Pronello, Cristina, Tyrinopoulos, Yannis
Published in Frontiers in future transportation (29.06.2023)
Published in Frontiers in future transportation (29.06.2023)
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Journal Article
Non-viral in vivo cytidine base editing in hepatocytes using focused ultrasound targeted microbubbles
Anderson, Cynthia D., Arthur, Jennifer Ataam, Zhang, Yuan, Bharucha, Nike, Karakikes, Ioannis, Shohet, Ralph V.
Published in Molecular therapy. Nucleic acids (12.09.2023)
Published in Molecular therapy. Nucleic acids (12.09.2023)
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