Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects
Cheng, Ya-Wen, Chao, Tai-Ling, Li, Chiao-Ling, Chiu, Mu-Fan, Kao, Han-Chieh, Wang, Sheng-Han, Pang, Yu-Hao, Lin, Chih-Hui, Tsai, Ya-Min, Lee, Wen-Hau, Tao, Mi-Hua, Ho, Tung-Ching, Wu, Ping-Yi, Jang, Li-Ting, Chen, Pei-Jer, Chang, Sui-Yuan, Yeh, Shiou-Hwei
Published in Cell Reports (13.10.2020)
Published in Cell Reports (13.10.2020)
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Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses
Chang, Sui-Yuan, Huang, Kuo-Yen, Chao, Tai-Ling, Kao, Han-Chieh, Pang, Yu-Hao, Lu, Lin, Chiu, Chun-Lun, Huang, Hsin-Chang, Cheng, Ting-Jen Rachel, Fang, Jim-Min, Yang, Pan-Chyr
Published in Scientific reports (22.04.2021)
Published in Scientific reports (22.04.2021)
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Humanized COVID‐19 decoy antibody effectively blocks viral entry and prevents SARS‐CoV‐2 infection
Huang, Kuo‐Yen, Lin, Ming‐Shiu, Kuo, Ting‐Chun, Chen, Ci‐Ling, Lin, Chung‐Chih, Chou, Yu‐Chi, Chao, Tai‐Ling, Pang, Yu‐Hao, Kao, Han‐Chieh, Huang, Rih‐Sheng, Lin, Steven, Chang, Sui‐Yuan, Yang, Pan‐Chyr
Published in EMBO molecular medicine (11.01.2021)
Published in EMBO molecular medicine (11.01.2021)
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D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Virus Titer via Enhanced Furin-Mediated Spike Cleavage
Cheng, Ya-Wen, Chao, Tai-Ling, Li, Chiao-Ling, Wang, Sheng-Han, Kao, Han-Chieh, Tsai, Ya-Min, Wang, Hurng-Yi, Hsieh, Chi-Ling, Lin, You-Yu, Chen, Pei-Jer, Chang, Sui-Yuan, Yeh, Shiou-Hwei
Published in mBio (31.08.2021)
Published in mBio (31.08.2021)
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Remdesivir and Cyclosporine Synergistically Inhibit the Human Coronaviruses OC43 and SARS-CoV-2
Hsu, Hsing-Yu, Yang, Cheng-Wei, Lee, Yue-Zhi, Lin, Yi-Ling, Chang, Sui-Yuan, Yang, Ruey-Bing, Liang, Jian-Jong, Chao, Tai-Ling, Liao, Chun-Che, Kao, Han-Chieh, Wu, Szu-Huei, Chang, Jang-Yang, Sytwu, Huey-Kang, Chen, Chiung-Tong, Lee, Shiow-Ju
Published in Frontiers in pharmacology (13.08.2021)
Published in Frontiers in pharmacology (13.08.2021)
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Inhibition of SARS-CoV-2 by Highly Potent Broad-Spectrum Anti-Coronaviral Tylophorine-Based Derivatives
Yang, Cheng-Wei, Lee, Yue-Zhi, Hsu, Hsing-Yu, Jan, Jia-Tsrong, Lin, Yi-Ling, Chang, Sui-Yuan, Peng, Tzu-Ting, Yang, Ruey-Bing, Liang, Jian-Jong, Liao, Chun-Che, Chao, Tai-Ling, Pang, Yu-Hau, Kao, Han-Chieh, Huang, Wen-Zheng, Lin, Jiunn-Horng, Chang, Chun-Ping, Niu, Guang-Hao, Wu, Szu-Huei, Sytwu, Huey-Kang, Chen, Chiung-Tong, Lee, Shiow-Ju
Published in Frontiers in pharmacology (14.12.2020)
Published in Frontiers in pharmacology (14.12.2020)
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Enhancement of the IFN-β-induced host signature informs repurposed drugs for COVID-19
Huang, Chen-Tsung, Chao, Tai-Ling, Kao, Han-Chieh, Pang, Yu-Hao, Lee, Wen-Hau, Hsieh, Chiao-Hui, Chang, Sui-Yuan, Huang, Hsuan-Cheng, Juan, Hsueh-Fen
Published in Heliyon (01.12.2020)
Published in Heliyon (01.12.2020)
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The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b
Lee, Yue-Zhi, Hsu, Hsing-Yu, Yang, Cheng-Wei, Lin, Yi-Ling, Chang, Sui-Yuan, Yang, Ruey-Bing, Liang, Jian-Jong, Chao, Tai-Ling, Liao, Chun-Che, Kao, Han-Chieh, Chang, Jang-Yang, Sytwu, Huey-Kang, Chen, Chiung-Tong, Lee, Shiow-Ju
Published in Pharmaceutics (21.07.2022)
Published in Pharmaceutics (21.07.2022)
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Kinetic Characterization and Inhibitor Screening for the Proteases Leading to Identification of Drugs against SARS-CoV-2
Kuo, Chih-Jung, Chao, Tai-Ling, Kao, Han-Chieh, Tsai, Ya-Min, Liu, Yi-Kai, Wang, Lily Hui-Ching, Hsieh, Ming-Chang, Chang, Sui-Yuan, Liang, Po-Huang
Published in Antimicrobial agents and chemotherapy (18.03.2021)
Published in Antimicrobial agents and chemotherapy (18.03.2021)
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Neutralization or enhancement of SARS-CoV-2 infection by a monoclonal antibody targeting a specific epitope in the spike receptor-binding domain
Lai, Guan-Chun, Chao, Tai-Ling, Lin, Shiau-Yu, Kao, Han-Chieh, Tsai, Ya-Min, Lu, De-Chao, Chiang, Yi-Wei, Chang, Sui-Yuan, Chang, Shih-Chung
Published in Antiviral research (01.04.2022)
Published in Antiviral research (01.04.2022)
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A siRNA targets and inhibits a broad range of SARS‐CoV‐2 infections including Delta variant
Chang, Yi‐Chung, Yang, Chi‐Fan, Chen, Yi‐Fen, Yang, Chia‐Chun, Chou, Yuan‐Lin, Chou, Hung‐Wen, Chang, Tein‐Yao, Chao, Tai‐Ling, Hsu, Shu‐Chen, Ieong, Si‐Man, Tsai, Ya‐Min, Liu, Ping‐Cheng, Chin, Yuan‐Fan, Fang, Jun‐Tung, Kao, Han‐Chieh, Lu, Hsuan‐Ying, Chang, Jia‐Yu, Weng, Ren‐Shiuan, Tu, Qian‐Wen, Chang, Fang‐Yu, Huang, Kuo‐Yen, Lee, Tong‐Young, Chang, Sui‐Yuan, Yang, Pan‐Chyr
Published in EMBO molecular medicine (07.04.2022)
Published in EMBO molecular medicine (07.04.2022)
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Correction: Lee et al. The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b. Pharmaceutics 2022, 14 , 1511
Lee, Yue-Zhi, Hsu, Hsing-Yu, Yang, Cheng-Wei, Lin, Yi-Ling, Chang, Sui-Yuan, Yang, Ruey-Bing, Liang, Jian-Jong, Chao, Tai-Ling, Liao, Chun-Che, Kao, Han-Chieh, Chang, Jang-Yang, Sytwu, Huey-Kang, Chen, Chiung-Tong, Lee, Shiow-Ju
Published in Pharmaceutics (19.01.2023)
Published in Pharmaceutics (19.01.2023)
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Correction: Lee et al. The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b. IPharmaceutics/I 2022, I14/I, 1511
Lee, Yue-Zhi, Hsu, Hsing-Yu, Yang, Cheng-Wei, Lin, Yi-Ling, Chang, Sui-Yuan, Yang, Ruey-Bing, Liang, Jian-Jong, Chao, Tai-Ling, Liao, Chun-Che, Kao, Han-Chieh, Chang, Jang-Yang, Sytwu, Huey-Kang, Chen, Chiung-Tong, Lee, Shiow-Ju
Published in Pharmaceutics (01.01.2023)
Published in Pharmaceutics (01.01.2023)
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D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Viral Transmission via Enhanced Furin-mediated Spike Cleavage
Ya-Wen, Cheng, Tai-Ling, Chao, Chiao-Ling, Li, Sheng-Han, Wang, Han-Chieh Kao, Ya-Min Tsai, Wang, Hurng-Yi, Chi-Ling Hsieh, Chen, Pei-Jer, Sui-Yuan, Chang, Yeh, Shiou-Hwei
Published in bioRxiv (28.01.2021)
Published in bioRxiv (28.01.2021)
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Distinct Inductions of and Responses to Type I and Type III Interferons Promote Infections in Two SARS-CoV-2 Isolates
Fu Hsin, Tai-Ling, Chao, Yun-Rui Chan, Han-Chieh Kao, Wang-Da, Liu, Jann-Tay Wang, Yu-Hao, Pang, Chih-Hui, Lin, Ya-Min Tsai, Jing-Yi, Lin, Sui-Yuan, Chang, Liu, Helene Minyi
Published in bioRxiv (01.05.2020)
Published in bioRxiv (01.05.2020)
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Impact of glycosylation on a broad-spectrum vaccine against SARS-CoV-2
Han-Yi, Huang, Hsin-Yu Liao, Chen, Xiaorui, Wang, Szu-Wen, Cheng-Wei, Cheng, Shahed-Al-Mahmud, Md, Ting-Hua, Chen, Lo, Jennifer M, Liu, Yo-Min, Yi-Min, Wu, Ma, Hsiu-Hua, Chang, Yi-Hsuan, Ho-Yang, Tsai, Yu-Chi, Chou, Yi-Ping Hsueh, Ching-Yen Tsai, Pau-Yi, Huang, Sui-Yuan, Chang, Tai-Ling, Chao, Han-Chieh Kao, Ya-Min Tsai, Yen-Hui, Chen, Chung-Yi, Wu, Jia-Tsrong, Jan, Ting-Jen, Rachel Cheng, Kuo-I, Lin, Ma, Che, Wong, Chi-Huey
Published in bioRxiv (26.08.2021)
Published in bioRxiv (26.08.2021)
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