Discovery of an Orally Bioavailable Benzimidazole Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor That Suppresses Body Weight Gain in Diet-Induced Obese Dogs and Postprandial Triglycerides in Humans
Nakajima, Katsumasa, Chatelain, Ricardo, Clairmont, Kevin B, Commerford, Renee, Coppola, Gary M, Daniels, Thomas, Forster, Cornelia J, Gilmore, Thomas A, Gong, Yongjin, Jain, Monish, Kanter, Aaron, Kwak, Youngshin, Li, Jingzhou, Meyers, Charles D, Neubert, Alan D, Szklennik, Paul, Tedesco, Vivienne, Thompson, James, Truong, David, Yang, Qing, Hubbard, Brian K, Serrano-Wu, Michael H
Published in Journal of medicinal chemistry (08.06.2017)
Published in Journal of medicinal chemistry (08.06.2017)
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FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES
ZECRI FREDERIC, KIRMAN LOUISE CLARE, BRUCE ALEXANDRA MARSHALL, BARNES DAVID WENINGER, LOU CHANGGANG, DUTTAROY ALOKESH, YUAN JUN, USERA AIMEE RICHARDSON, KANTER AARON, BOSE AVIRUP, IBEBUNJO CHIKWENDU, YAMADA KEN
Year of Publication 27.04.2023
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Year of Publication 27.04.2023
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Discovery of diamide compounds as diacylglycerol acyltransferase 1 (DGAT1) inhibitors
Nakajima, Katsumasa, April, Myriam, Brewer, Jason T., Daniels, Thomas, Forster, Cornelia J., Gilmore, Thomas A., Jain, Monish, Kanter, Aaron, Kwak, Youngshin, Li, Jingzhou, McQuire, Les, Serrano-Wu, Michael H., Streeper, Ryan, Szklennik, Paul, Thompson, James, Wang, Bing
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
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Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors
Arcari, Joel T., Beebe, Jean S., Berliner, Martin A., Bernardo, Vincent, Boehm, Merin, Borzillo, Gary V., Clark, Tracey, Cohen, Bruce D., Connell, Richard D., Frost, Heather N., Gordon, Deborah A., Hungerford, William M., Kakar, Shefali M., Kanter, Aaron, Keene, Nandell F., Knauth, Elizabeth A., LaGreca, Susan D., Lu, Yong, Martinez-Alsina, Louis, Marx, Matthew A., Morris, Joel, Patel, Nandini C., Savage, Doug, Soderstrom, Cathy I., Thompson, Carl, Tkalcevic, George, Tom, Norma J., Vajdos, Felix F., Valentine, James J., Vincent, Patrick W., Wessel, Matthew D., Chen, Jinshan M.
Published in Bioorganic & medicinal chemistry letters (15.05.2013)
Published in Bioorganic & medicinal chemistry letters (15.05.2013)
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FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES
ZECRI FREDERIC, KIRMAN LOUISE CLARE, BRUCE ALEXANDRA MARSHALL, BARNES DAVID WENINGER, LOU CHANGGANG, DUTTAROY ALOKESH, YUAN JUN, USERA AIMEE RICHARDSON, KANTER AARON, BOSE AVIRUP, IBEBUNJO CHIKWENDU, YAMADA KEN
Year of Publication 24.02.2017
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Year of Publication 24.02.2017
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A new structural alert for benzimidazoles: 2,6-Dimethylphenyl substituents increase mutagenic potential and time-dependent CYP3A4 inhibition risk
Kwak, Youngshin, Coppola, Gary, Forster, Cornelia J., Gilmore, Thomas A., Gong, Yongjin, Kanter, Aaron, Neubert, Alan, Stroup, Bryan, Szklennik, Paul, Glowienke, Susanne, Stadelmann, Pascal, Bell, Leslie, Bickford, Shari, Gangl, Eric, Gunduz, Mithat, Jain, Monish, Zhan, Jenny, Serrano-Wu, Michael H.
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
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CYCLIC POLYPEPTIDES FOR THE TREATMENT OF HEART FAILURE
GUIMARAES CARLA, YASOSHIMA KAYO, ZECRI FREDERIC, BRUCE ALEXANDRA MARSHALL, LOU CHANGGANG, ZHAO HONGJUAN, GROSCHE PHILIPP, YUAN JUN, KANTER AARON, USERA AIMEE RICHARDSON
Year of Publication 22.03.2016
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Year of Publication 22.03.2016
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BIOCONJUGATES OF SYNTHETIC APELIN POLYPEPTIDES
GUIMARAES CARLA, YASOSHIMA KAYO, ZECRI FREDERIC, ZHAO HONGJUAN, YUAN JUN, PARKER DAVID THOMAS, PETERS ERIC C, GOLOSOV ANDREI, LOU CHANGGANG, GROSCHE PHILIPP, CAPLAN SHARI L, KANTER AARON, USERA AIMEE RICHARDSON
Year of Publication 22.03.2016
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Year of Publication 22.03.2016
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Designing Protein Dimerizers: The Importance of Ligand Conformational Equilibria
Carlson, Jonathan C. T., Kanter, Aaron, Thuduppathy, Guruvasuthevan R., Cody, Vivian, Pineda, Pamela E., McIvor, R. Scott, Wagner, Carston R.
Published in Journal of the American Chemical Society (12.02.2003)
Published in Journal of the American Chemical Society (12.02.2003)
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Fatty acids and their use in conjugation to biomolecules
Kanter, Aaron, Yuan, Jun, Bruce, Alexandra Marshall, Zecri, Frederic, Usera, Aimee Richardson
Year of Publication 12.09.2023
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Year of Publication 12.09.2023
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NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES
ZECRI, Frederic, BARNES, David Weninger, YUAN, Jun, LOU, Changgang, KANTER, Aaron, USERA, Aimee Richardson, DUTTAROY, Alokesh, BOSE, Avirup, BRUCE, Alexandra Marshall, KIRMAN, Louise Clare, YAMADA, Ken, IBEBUNJO, Chikwendu
Year of Publication 29.02.2024
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Year of Publication 29.02.2024
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