NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models
Charych, Deborah H, Hoch, Ute, Langowski, John L, Lee, Steve R, Addepalli, Murali K, Kirk, Peter B, Sheng, Dawei, Liu, Xiaofeng, Sims, Paul W, VanderVeen, Laurie A, Ali, Cherie F, Chang, Thomas K, Konakova, Marina, Pena, Rhoneil L, Kanhere, Rupesh S, Kirksey, Yolanda M, Ji, Chunmei, Wang, Yujun, Huang, Jicai, Sweeney, Theresa D, Kantak, Seema S, Doberstein, Stephen K
Published in Clinical cancer research (01.02.2016)
Published in Clinical cancer research (01.02.2016)
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Journal Article
Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice
Bhaskar, Vinay, Yin, Johnny, Mirza, Amer M, Phan, Dan, Vanegas, Sandra, Issafras, Hassan, Michelson, Kristen, Hunter, John J, Kantak, Seema S
Published in Atherosclerosis (01.06.2011)
Published in Atherosclerosis (01.06.2011)
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Journal Article
Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1β Activity
Roell, Marina K., Issafras, Hassan, Bauer, Robert J., Michelson, Kristen S., Mendoza, Nerissa, Vanegas, Sandra I., Gross, Lisa M., Larsen, Paul D., Bedinger, Daniel H., Bohmann, David J., Nonet, Genevieve H., Liu, Naichi, Lee, Steve R., Handa, Masahisa, Kantak, Seema S., Horwitz, Arnold H., Hunter, John J., Owyang, Alexander M., Mirza, Amer M., Corbin, John A., White, Mark L.
Published in The Journal of biological chemistry (02.07.2010)
Published in The Journal of biological chemistry (02.07.2010)
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Journal Article
Dominant-negative E-cadherin alters adhesion and reverses contact inhibition of growth in breast carcinoma cells
Vizirianakis, Ioannis S, Chen, Yao-Qi, Kantak, Seema S, Tsiftsoglou, Asterios S, Kramer, Randall H
Published in International journal of oncology (01.07.2002)
Published in International journal of oncology (01.07.2002)
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Journal Article
Radiation Induced Endothelial Cell Retraction in vitro: Correlation with Acute Pulmonary Edema
Onoda, James M, Kantak, Seema S, Diglio, Clement A
Published in Pathology oncology research (01.03.1999)
Published in Pathology oncology research (01.03.1999)
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Journal Article
Combination between a long-acting engineered cytokine (NKTR-214) and checkpoint inhibitors anti-CTLA-4 or anti-PD1 in murine tumor models
Kantak, Seema S., Lee, Steve, Addepalli, Murali, Hoch, Ute, Pena, Rhoneil, Kirksey, Yolanda, Charych, Deborah H., Doberstein, Stephen K.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
An engineered immunotherapy (NKTR-214) with altered selectivity toward the IL2 receptor: Efficacy and tolerability in a murine tumor model
Charych, Deborah H., Addepalli, Murali, Lee, Steve, Chang, Thomas, Liu, Xiaofeng, Pena, Rhoneil, Sweeney, Terry, Hoch, Ute, Doberstein, Stephen K., Kantak, Seema S.
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
Integrin α3β1 Engagement Disrupts Intercellular Adhesion
Kawano, Kenji, Kantak, Seema S., Murai, Mutsuhiko, Yao, Chung-Chen, Kramer, Randall H.
Published in Experimental cell research (15.01.2001)
Published in Experimental cell research (15.01.2001)
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Journal Article
Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1b Activity
Roell, Marina K, Issafras, Hassan, Bauer, Robert J, Michelson, Kristen S, Mendoza, Nerissa, Vanegas, Sandra I, Gross, Lisa M, Larsen, Paul D, Bedinger, Daniel H, Bohmann, David J, Nonet, Genevieve H, Liu, Naichi, Lee, Steve R, Handa, Masahisa, Kantak, Seema S, Horwitz, Arnold H, Hunter, John J, Owyang, Alexander M, Mirza, Amer M, Corbin, John A, White, Mark L
Published in The Journal of biological chemistry (01.07.2010)
Published in The Journal of biological chemistry (01.07.2010)
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Journal Article
Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity
Roell, Marina K, Issafras, Hassan, Bauer, Robert J, Michelson, Kristen S, Mendoza, Nerissa, Vanegas, Sandra I, Gross, Lisa M, Larsen, Paul D, Bedinger, Daniel H, Bohmann, David J, Nonet, Genevieve H, Liu, Naichi, Lee, Steve R, Handa, Masahisa, Kantak, Seema S, Horwitz, Arnold H, Hunter, John J, Owyang, Alexander M, Mirza, Amer M, Corbin, John A, White, Mark L
Published in The Journal of biological chemistry (02.07.2010)
Published in The Journal of biological chemistry (02.07.2010)
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Journal Article
5T4 antibody-drug conjugates and uses thereof
OGUNKOYA, AYODELE, DRAKE, PENELOPE M, BARFIELD, ROBYN M, CHUPRAKOV, STEPAN, MENDELSOHN, BRIAN ALAN, KANTAK, SEEMA
Year of Publication 01.03.2024
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Year of Publication 01.03.2024
Patent
VE-Cadherin binding bioconjugate
PANITCH, ALYSSA, STUART, KATHERINE ALLISON, PADERI, JOHN ERIC, BACHTELL, NATHAN, KANTAK, SEEMA
Year of Publication 01.06.2017
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Year of Publication 01.06.2017
Patent
Uses of anti-cd40 antibodies
KANTAK SEEMA, WANG YONGYU, MIRZA AMER M, HSU SSUCHENG J, LUQMAN MOHAMMAD
Year of Publication 09.02.2011
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Year of Publication 09.02.2011
Patent
Fully human anti-VEGF antibodies and methods of using
BISHOP ROBERT WALTER, TAKEUCHI TOSHIHIKO, KANTAK SEEMA, HUANG QINGYI, HUANG CHAOBAI, RAMACHANDRA SUMANT, MASAT LINDA
Year of Publication 15.12.2010
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Year of Publication 15.12.2010
Patent