A bromopyrrole-containing diterpene alkaloid from the Okinawan marine sponge Agelas nakamurai activates the insulin pathway in Huh-7 human hepatoma cells by inhibiting protein tyrosine phosphatase 1B
Yamazaki, Hiroyuki, Kanno, Syu-ichi, Abdjul, Delfly B., Namikoshi, Michio
Published in Bioorganic & medicinal chemistry letters (15.05.2017)
Published in Bioorganic & medicinal chemistry letters (15.05.2017)
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Journal Article
Structures and Biological Evaluations of Agelasines Isolated from the Okinawan Marine Sponge Agelas nakamurai
Abdjul, Delfly B, Yamazaki, Hiroyuki, Kanno, Syu-ichi, Takahashi, Ohgi, Kirikoshi, Ryota, Ukai, Kazuyo, Namikoshi, Michio
Published in Journal of natural products (Washington, D.C.) (26.06.2015)
Published in Journal of natural products (Washington, D.C.) (26.06.2015)
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Journal Article
A dimeric urea of the bisabolene sesquiterpene from the Okinawan marine sponge Axinyssa sp. inhibits protein tyrosine phosphatase 1B activity in Huh-7 human hepatoma cells
Abdjul, Delfly B., Kanno, Syu-ichi, Yamazaki, Hiroyuki, Ukai, Kazuyo, Namikoshi, Michio
Published in Bioorganic & medicinal chemistry letters (15.01.2016)
Published in Bioorganic & medicinal chemistry letters (15.01.2016)
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Journal Article
Pifithrin-alpha has a p53-independent cytoprotective effect on docosahexaenoic acid-induced cytotoxicity in human hepatocellular carcinoma HepG2 cells
Kanno, Syu-ichi, Kurauchi, Kaori, Tomizawa, Ayako, Yomogida, Shin, Ishikawa, Masaaki
Published in Toxicology letters (22.01.2015)
Published in Toxicology letters (22.01.2015)
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Journal Article
Alterations in prefrontal cortical neuregulin-1 levels in post-pubertal rats with neonatal ventral hippocampal lesions
Watanabe, Kenya, Nakagawasai, Osamu, Kanno, Syu-Ichi, Mitazaki, Satoru, Onogi, Hiroshi, Takahashi, Kohei, Watanabe, Kei-Ichiro, Tan-No, Koichi, Ishikawa, Masaaki, Srivastava, Lalit K, Quirion, Remi, Tadano, Takeshi
Published in Frontiers in behavioral neuroscience (22.12.2022)
Published in Frontiers in behavioral neuroscience (22.12.2022)
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Journal Article
Haliclonadiamine Derivatives and 6-epi-Monanchorin from the Marine Sponge Halichondria panicea Collected at Iriomote Island
Abdjul, Delfly B, Yamazaki, Hiroyuki, Kanno, Syu-ichi, Takahashi, Ohgi, Kirikoshi, Ryota, Ukai, Kazuyo, Namikoshi, Michio
Published in Journal of natural products (Washington, D.C.) (22.04.2016)
Published in Journal of natural products (Washington, D.C.) (22.04.2016)
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Journal Article
Biphenyl ether derivatives with protein tyrosine phosphatase 1B inhibitory activity from the freshwater fungus Phoma sp
Sumilat, Deiske A, Yamazaki, Hiroyuki, Kanno, Syu-ichi, Saito, Ryo, Watanabe, Yuta, Namikoshi, Michio
Published in Journal of antibiotics (01.03.2017)
Published in Journal of antibiotics (01.03.2017)
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Journal Article
Inhibitory Effects of Naringenin on Tumor Growth in Human Cancer Cell Lines and Sarcoma S-180-Implanted Mice
Kanno, Syu-ichi, Tomizawa, Ayako, Hiura, Takako, Osanai, Yuu, Shouji, Ai, Ujibe, Mayuko, Ohtake, Takaharu, Kimura, Katsuhiko, Ishikawa, Masaaki
Published in Biological & pharmaceutical bulletin (01.03.2005)
Published in Biological & pharmaceutical bulletin (01.03.2005)
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Journal Article
Absolute Structures of Wedelolide Derivatives and Structure–Activity Relationships of Protein Tyrosine Phosphatase 1B Inhibitory ent-Kaurene Diterpenes from Aerial Parts of Wedelia spp. Collected in Indonesia and Japan
Abdjul, Delfly Booby, Yamazaki, Hiroyuki, Kanno, Syu-ichi, Kirikoshi, Ryota, Tomizawa, Ayako, Takahashi, Ohgi, Maarisit, Wilmar, Losung, Fitje, Rotinsulu, Henki, Wewengkang, Defny Silvia, Sumilat, Deiske Adeliene, Kapojos, Magie Melanie, Namikoshi, Michio
Published in Chemical & pharmaceutical bulletin (01.06.2018)
Published in Chemical & pharmaceutical bulletin (01.06.2018)
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Journal Article
Structures and biological activities of triterpenes and sesquiterpenes obtained from Russula lepida
Lee, Jong-Soo, Maarisit, Wilmar, Abdjul, Delfly B., Yamazaki, Hiroyuki, Takahashi, Ohgi, Kirikoshi, Ryota, Kanno, Syu-ichi, Namikoshi, Michio
Published in Phytochemistry (Oxford) (01.07.2016)
Published in Phytochemistry (Oxford) (01.07.2016)
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Journal Article
polybromodiphenyl ether from an Indonesian marine sponge Lamellodysidea herbacea and its chemical derivatives inhibit protein tyrosine phosphatase 1B, an important target for diabetes treatment
Yamazaki, Hiroyuki, Sumilat, Deiske A, Kanno, Syu-ichi, Ukai, Kazuyo, Rotinsulu, Henki, Wewengkang, Defny S, Ishikawa, Masaaki, Mangindaan, Remy E. P, Namikoshi, Michio
Published in Journal of natural medicines (01.10.2013)
Published in Journal of natural medicines (01.10.2013)
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Journal Article
Highly Efficient Total Synthesis of the Marine Natural Products (+)-Avarone, (+)-Avarol, (−)-Neoavarone, (−)-Neoavarol and (+)-Aureol
Sakurai, Junji, Oguchi, Takamasa, Watanabe, Kazuhiro, Abe, Hideki, Kanno, Syu-ichi, Ishikawa, Masaaki, Katoh, Tadashi
Published in Chemistry : a European journal (01.01.2008)
Published in Chemistry : a European journal (01.01.2008)
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Journal Article
Absolute structures and bioactivities of euryspongins and eurydiene obtained from the marine sponge Euryspongia sp. collected at Iriomote Island
Yamazaki, Hiroyuki, Takahashi, Ohgi, Kanno, Syu-ichi, Nakazawa, Takahiro, Takahashi, Shiori, Ukai, Kazuyo, Sumilat, Deiske A., Ishikawa, Masaaki, Namikoshi, Michio
Published in Bioorganic & medicinal chemistry (15.02.2015)
Published in Bioorganic & medicinal chemistry (15.02.2015)
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Journal Article
Angiotensin II Produces Nociceptive Behavior through Spinal AT1 Receptor-Mediated p38 Mitogen-Activated Protein Kinase Activation in Mice
Nemoto, Wataru, Nakagawasai, Osamu, Yaoita, Fukie, Kanno, Syu-Ichi, Yomogida, Shin, Ishikawa, Masaaki, Tadano, Takeshi, Tan-No, Koichi
Published in Molecular pain (31.07.2013)
Published in Molecular pain (31.07.2013)
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Journal Article
Papuamine causes autophagy following the reduction of cell survival through mitochondrial damage and JNK activation in MCF-7 human breast cancer cells
Kanno, Syu-Ichi, Yomogida, Shin, Tomizawa, Ayako, Yamazaki, Hiroyuki, Ukai, Kazuyo, Mangindaan, Remy E P, Namikoshi, Michio, Ishikawa, Masaaki
Published in International journal of oncology (01.11.2013)
Published in International journal of oncology (01.11.2013)
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Journal Article
Inhibitory effect of naringin on lipopolysaccharide (LPS)-induced endotoxin shock in mice and nitric oxide production in RAW 264.7 macrophages
Kanno, Syu-ichi, Shouji, Ai, Tomizawa, Ayako, Hiura, Takako, Osanai, Yuu, Ujibe, Mayuko, Obara, Yutaro, Nakahata, Norimichi, Ishikawa, Masaaki
Published in Life sciences (1973) (11.01.2006)
Published in Life sciences (1973) (11.01.2006)
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Journal Article
An anti-mycobacterial bisfunctionalized sphingolipid and new bromopyrrole alkaloid from the Indonesian marine sponge Agelas sp
Abdjul, Delfly B., Yamazaki, Hiroyuki, Kanno, Syu-ichi, Tomizawa, Ayako, Rotinsulu, Henki, Wewengkang, Defny S., Sumilat, Deiske A., Ukai, Kazuyo, Kapojos, Magie M., Namikoshi, Michio
Published in Journal of natural medicines (01.07.2017)
Published in Journal of natural medicines (01.07.2017)
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Journal Article
Protein tyrosine phosphatase 1B inhibitory properties of seco-cucurbitane triterpenes obtained from fruiting bodies of Russula lepida
Maarisit, Wilmar, Yamazaki, Hiroyuki, Kanno, Syu-ichi, Tomizawa, Ayako, Lee, Jong-Soo, Namikoshi, Michio
Published in Journal of natural medicines (01.01.2017)
Published in Journal of natural medicines (01.01.2017)
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Journal Article