Mephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the rat
Meng, Harry, Cao, James, Kang, Jiesheng, Ying, Xiaoyou, Ji, Junzhi, Reynolds, William, Rampe, David
Published in Toxicology letters (05.01.2012)
Published in Toxicology letters (05.01.2012)
Get full text
Journal Article
Pentamidine-Induced Long QT Syndrome and Block of hERG Trafficking
Kuryshev, Yuri A, Ficker, Eckhard, Wang, Lu, Hawryluk, Peter, Dennis, Adrienne T, Wible, Barbara A, Brown, Arthur M, Kang, Jiesheng, Chen, Xiao-Liang, Sawamura, Kaoru, Reynolds, William, Rampe, David
Published in The Journal of pharmacology and experimental therapeutics (01.01.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2005)
Get full text
Journal Article
Discovery of a Small Molecule Activator of the Human Ether-a-go-go-Related Gene (HERG) Cardiac K+ Channel
Kang, Jiesheng, Chen, Xiao-Liang, Wang, Hongge, Ji, Junzhi, Cheng, Hsien, Incardona, Josephine, Reynolds, William, Viviani, Fabrice, Tabart, Michel, Rampe, David
Published in Molecular pharmacology (01.03.2005)
Published in Molecular pharmacology (01.03.2005)
Get full text
Journal Article
Interactions of a Series of Fluoroquinolone Antibacterial Drugs with the Human Cardiac K+ Channel HERG
Kang, J, Wang, L, Chen, X L, Triggle, D J, Rampe, D
Published in Molecular pharmacology (01.01.2001)
Published in Molecular pharmacology (01.01.2001)
Get full text
Journal Article
Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches
Pearlstein, Robert A, Vaz, Roy J, Kang, Jiesheng, Chen, Xiao-Liang, Preobrazhenskaya, Maria, Shchekotikhin, Andrey E, Korolev, Alexander M, Lysenkova, Ludmila N, Miroshnikova, Olga V, Hendrix, James, Rampe, David
Published in Bioorganic & medicinal chemistry letters (19.05.2003)
Published in Bioorganic & medicinal chemistry letters (19.05.2003)
Get full text
Journal Article
A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity
Liang, Guyan, Choi-Sledeski, Yong Mi, Shum, Patrick, Chen, Xin, Poli, Gregory B., Kumar, Vasant, Minnich, Anne, Wang, Qingping, Tsay, Joseph, Sides, Keith, Kang, Jiesheng, Zhang, Ying
Published in Bioorganic & medicinal chemistry letters (15.02.2012)
Published in Bioorganic & medicinal chemistry letters (15.02.2012)
Get full text
Journal Article
Predictive models for hERG potassium channel blockers
Cianchetta, Giovanni, Li, Yi, Kang, Jiesheng, Rampe, David, Fravolini, Arnaldo, Cruciani, Gabriele, Vaz, Roy J.
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
Get full text
Journal Article
Mechanisms underlying the QT interval-prolonging effects of sevoflurane and its interactions with other QT-prolonging drugs
JIESHENG KANG, REYNOLDS, William P, CHEN, Xiao-Liang, JUNZHI JI, HONGGE WANG, RAMPE, David E
Published in Anesthesiology (Philadelphia) (01.05.2006)
Published in Anesthesiology (Philadelphia) (01.05.2006)
Get full text
Journal Article
High affinity blockade of the HERG cardiac K + channel by the neuroleptic pimozide
Kang, Jiesheng, Wang, Lin, Cai, Feng, Rampe, David
Published in European journal of pharmacology (31.03.2000)
Published in European journal of pharmacology (31.03.2000)
Get full text
Journal Article
Cardiac Ion Channel Effects of Tolterodine
Kang, Jiesheng, Chen, Xiao-Liang, Wang, Hongge, Ji, Junzhi, Reynolds, William, Lim, Sungtaek, Hendrix, James, Rampe, David
Published in The Journal of pharmacology and experimental therapeutics (01.03.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2004)
Get full text
Journal Article
Design of bivalent ligands using hydrogen bond linkers: synthesis and evaluation of inhibitors for human β-tryptase
Vaz, Roy J., Gao, Zhongli, Pribish, James, Chen, Xin, Levell, Julian, Davis, Larry, Albert, Eva, Brollo, Maurice, Ugolini, Antonio, Cramer, Dona M., Cairns, Jennifer, Sides, Keith, Liu, Feng, Kwong, Jennifer, Kang, Jiesheng, Rebello, Sam, Elliot, Michael, Lim, HengKeang, Chellaraj, Vinolia, Singleton, Robert W., Li, Yi
Published in Bioorganic & medicinal chemistry letters (20.12.2004)
Published in Bioorganic & medicinal chemistry letters (20.12.2004)
Get full text
Journal Article
Observations on conducting whole‐cell patch clamping of the hERG cardiac K+ channel in pure human serum
Kang, Jiesheng, Luo, Yongyi, Searles, Michelle, Rampe, David
Published in Journal of applied toxicology (01.04.2017)
Published in Journal of applied toxicology (01.04.2017)
Get full text
Journal Article
Ca²⁺ channel activators reveal differential L-type Ca²⁺ channel pharmacology between native and stem cell-derived cardiomyocytes
Kang, Jiesheng, Chen, Xiao-Liang, Ji, Junzhi, Lei, Qiubo, Rampe, David
Published in The Journal of pharmacology and experimental therapeutics (01.05.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2012)
Get full text
Journal Article