The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections
Hickman, Mark R, Saunders, David L, Bigger, Catherine A, Kane, Christopher D, Iversen, Patrick L
Published in PLoS neglected tropical diseases (01.03.2022)
Published in PLoS neglected tropical diseases (01.03.2022)
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African and Asian Zika Virus Isolates Display Phenotypic Differences Both In Vitro and In Vivo
Smith, Darci R, Sprague, Thomas R, Hollidge, Bradley S, Valdez, Stephanie M, Padilla, Susana L, Bellanca, Stephanie A, Golden, Joseph W, Coyne, Susan R, Kulesh, David A, Miller, Lynn Jean, Haddow, Andrew D, Koehler, Jeff W, Gromowski, Gregory D, Jarman, Richard G, Alera, Maria Theresa P, Yoon, In-Kyu, Buathong, Rome, Lowen, Robert G, Kane, Christopher D, Minogue, Timothy D, Bavari, Sina, Tesh, Robert B, Weaver, Scott C, Linthicum, Kenneth J, Pitt, Margaret L, Nasar, Farooq
Published in The American journal of tropical medicine and hygiene (01.01.2018)
Published in The American journal of tropical medicine and hygiene (01.01.2018)
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Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus
Warren, Travis K., Kane, Christopher D., Wells, Jay, Stuthman, Kelly S., Van Tongeren, Sean A., Garza, Nicole L., Donnelly, Ginger, Steffens, Jesse, Gomba, Laura, Weidner, Jessica M., Norris, Sarah, Zeng, Xiankun, Bannister, Roy, Cihlar, Tomas, Bavari, Sina, Porter, Danielle P., Iversen, Patrick L.
Published in Scientific reports (30.09.2021)
Published in Scientific reports (30.09.2021)
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Recent advances in botulinum neurotoxin inhibitor development
Kiris, Erkan, Burnett, James C, Kane, Christopher D, Bavari, Sina
Published in Current topics in medicinal chemistry (01.01.2014)
Published in Current topics in medicinal chemistry (01.01.2014)
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Vinyl Sulfone-Based Inhibitors of Nonstructural Protein 2 Block the Replication of Venezuelan Equine Encephalitis Virus
Zhang, Huaisheng, Harmon, Moeshia, Radoshitzky, Sheli R, Soloveva, Veronica, Kane, Christopher D, Duplantier, Allen J, Ogungbe, Ifedayo Victor
Published in ACS medicinal chemistry letters (12.11.2020)
Published in ACS medicinal chemistry letters (12.11.2020)
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Clinical Laboratory Values as Early Indicators of Ebola Virus Infection in Nonhuman Primates
Reisler, Ronald B, Yu, Chenggang, Donofrio, Michael J, Warren, Travis K, Wells, Jay B, Stuthman, Kelly S, Garza, Nicole L, Vantongeren, Sean A, Donnelly, Ginger C, Kane, Christopher D, Kortepeter, Mark G, Bavari, Sina, Cardile, Anthony P
Published in Emerging infectious diseases (01.08.2017)
Published in Emerging infectious diseases (01.08.2017)
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Early detection of Ebola virus proteins in peripheral blood mononuclear cells from infected mice
Ward, Michael D, Kenny, Tara, Bruggeman, Ernie, Kane, Christopher D, Morrell, Courtney L, Kane, Molly M, Bixler, Sandra, Grady, Sarah L, Quizon, Rachel S, Astatke, Mekbib, Cazares, Lisa H
Published in Clinical proteomics (17.03.2020)
Published in Clinical proteomics (17.03.2020)
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Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays
Kiris, Erkan, Nuss, Jonathan E, Stanford, Stephanie M, Wanner, Laura M, Cazares, Lisa, Maestre, Michael F, Du, Hao T, Gomba, Glenn Y, Burnett, James C, Gussio, Rick, Bottini, Nunzio, Panchal, Rekha G, Kane, Christopher D, Tessarollo, Lino, Bavari, Sina
Published in PloS one (10.06.2015)
Published in PloS one (10.06.2015)
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The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding
Francone, Omar L., Tu, Meihua, Royer, Lori J., Zhu, Jian, Stevens, Kimberly, Oleynek, Joseph J., Lin, Zhiwu, Shelley, Lorraine, Sand, Thomas, Luo, Yi, Kane, Christopher D.
Published in Journal of lipid research (01.03.2009)
Published in Journal of lipid research (01.03.2009)
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Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis
Burmester, Gerd R, Weinblatt, Michael E, McInnes, Iain B, Porter, Duncan, Barbarash, Olga, Vatutin, Mykola, Szombati, Istvan, Esfandiari, Ehsanollah, Sleeman, Matthew A, Kane, Christopher D, Cavet, Guy, Wang, Bing, Godwood, Alex, Magrini, Fabio
Published in Annals of the rheumatic diseases (01.09.2013)
Published in Annals of the rheumatic diseases (01.09.2013)
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Journal Article
Recent successes in therapeutics for Ebola virus disease: no time for complacency
Iversen, Patrick L, Kane, Christopher D, Zeng, Xiankun, Panchal, Rekha G, Warren, Travis K, Radoshitzky, Sheli R, Kuhn, Jens H, Mudhasani, Rajini R, Cooper, Christopher L, Shurtleff, Amy C, Nasar, Farooq, Sunay, Melek ME, Duplantier, Allen J, Eaton, Brett P, Zumbrun, Elizabeth E, Bixler, Sandra L, Martin, Shannon, Meinig, J Matthew, Chiang, Chih-Yuan, Sanchez-Lockhart, Mariano, Palacios, Gustavo F, Kugelman, Jeffrey R, Martins, Karen A, Pitt, Margaret L, Crozier, Ian, Saunders, David L
Published in The Lancet infectious diseases (01.09.2020)
Published in The Lancet infectious diseases (01.09.2020)
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In Vitro and In Vivo Characterization of Tebipenem (TBP), an Orally Active Carbapenem, against Biothreat Pathogens
Clayton, Nicholas P, Jain, Akash, Halasohoris, Stephanie A, Pysz, Lisa M, Lembirik, Sanae, Zumbrun, Steven D, Kane, Christopher D, Hackett, Michael J, Pfefferle, Denise, Smiley, M Autumn, Anderson, Michael S, Heine, Henry, Meister, Gabriel T, Pucci, Michael J
Published in Antimicrobial agents and chemotherapy (01.05.2021)
Published in Antimicrobial agents and chemotherapy (01.05.2021)
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Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo
Pessi, Antonello, Bixler, Sandra L., Soloveva, Veronica, Radoshitzky, Sheli, Retterer, Cary, Kenny, Tara, Zamani, Rouzbeh, Gomba, Glenn, Gharabeih, Dima, Wells, Jay, Wetzel, Kelly S., Warren, Travis K., Donnelly, Ginger, Van Tongeren, Sean A., Steffens, Jesse, Duplantier, Allen J., Kane, Christopher D., Vicat, Pascale, Couturier, Valerie, Kester, Kent E., Shiver, John, Carter, Kara, Bavari, Sina
Published in Antiviral research (01.11.2019)
Published in Antiviral research (01.11.2019)
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Journal Article
Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery
Kiris, Erkan, Kota, Krishna P, Burnett, James C, Soloveva, Veronica, Kane, Christopher D, Bavari, Sina
Published in Expert review of molecular diagnostics (01.03.2014)
Published in Expert review of molecular diagnostics (01.03.2014)
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Journal Article
Countering Zika Virus: The USAMRIID Response
Lowen, Robert G, Bocan, Thomas M, Kane, Christopher D, Cazares, Lisa H, Kota, Krishna P, Ladner, Jason T, Nasar, Farooq, Pitt, Louise, Smith, Darci R, Soloveva, Veronica, Sun, Mei G, Zeng, Xiankun, Bavari, Sina
Published in Advances in experimental medicine and biology (01.01.2018)
Published in Advances in experimental medicine and biology (01.01.2018)
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Proteomic Analysis of Calcium/Calmodulin-dependent Protein Kinase I and IV in Vitro Substrates Reveals Distinct Catalytic Preferences
Corcoran, Ethan E, Joseph, James D, MacDonald, Justin A, Kane, Christopher D, Haystead, Timothy A J, Means, Anthony R
Published in The Journal of biological chemistry (21.03.2003)
Published in The Journal of biological chemistry (21.03.2003)
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Journal Article
Src Family Kinase Inhibitors Antagonize the Toxicity of Multiple Serotypes of Botulinum Neurotoxin in Human Embryonic Stem Cell-Derived Motor Neurons
Kiris, Erkan, Burnett, James C., Nuss, Jonathan E., Wanner, Laura M., Peyser, Brian D., Du, Hao T., Gomba, Glenn Y., Kota, Krishna P., Panchal, Rekha G., Gussio, Rick, Kane, Christopher D., Tessarollo, Lino, Bavari, Sina
Published in Neurotoxicity research (01.05.2015)
Published in Neurotoxicity research (01.05.2015)
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