Isc10, an inhibitor of the Smk1 MAPK, prevents activation loop autophosphorylation and substrate phosphorylation through separate mechanisms
Rimal, Abhimannyu, Swayne, Thomas M., Kamdar, Zeal P., Tewey, Madison A., Winter, Edward
Published in The Journal of biological chemistry (01.10.2022)
Published in The Journal of biological chemistry (01.10.2022)
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Isc10 is a Dual Mechanism Inhibitor of CMGC Kinases
Rimal, Abhimannyu, Swayne, Thomas M, Kamdar, Zeal P, Tewey, Madison A, Winter, Edward
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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897-B A DNAJB1-PRKACA fusion peptide vaccine combined with ipilimumab and nivolumab elicits polyclonal fusion-specific T cell responses in fibrolamellar carcinoma
Kirk, Allison M, Crawford, Jeremy C, Kamdar, Zeal, Baretti, Marina, Yarchoan, Mark, Thomas, Paul G
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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641 A pilot study of a DNAJB1-PRKACA fusion kinase peptide vaccine combined with nivolumab and ipilimumab for patients with fibrolamellar hepatocellular carcinoma
Baretti, Marina, Ladle, Brian, Nauroth, Julie, Wang, Hao, Durham, Jennifer, Thoburn, Christopher, Ferguson, Anna, Thompson, Alex, Brancati, Madalena, Griffith, Paige, Kamdar, Zeal, Kirk, Allison, Zaidi, Neeha, Huff, Amanda, Ho, Won, Furth, Mark, Thomas, Paul, Jaffee, Elizabeth M, Yarchoan, Mark
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Glutamine antagonist DRP-104 in combination with durvalumab in patients with advanced fibrolamellar carcinoma (FLC) following progression on prior anti-PD(L)1 therapy
Nakazawa, Mari, Kamdar, Zeal, Thomas, Amy, Durham, Jennifer N., Nauroth, Julie, Wang, Hao, Ladle, Brian H., Dykstra, Steven, Dugan, Margaret, Lafleur, Francois, Furth, Mark E., Leone, Robert D., Jaffee, Elizabeth M., Yarchoan, Mark, Baretti, Marina
Published in Journal of clinical oncology (20.01.2024)
Published in Journal of clinical oncology (20.01.2024)
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Profiling of syngeneic mouse HCC tumor models as a framework to understand anti-PD-1 sensitive tumor microenvironments
Zabransky, Daniel J, Danilova, Ludmila, Leatherman, James M, Lopez-Vidal, Tamara Y, Sanchez, Jessica, Charmsaz, Soren, Gross, Nicole E, Shin, Sarah, Yuan, Xuan, Hernandez, Alexei, Yang, Hongqui, Xavier, Stephanie, Shu, Daniel, Saeed, Ali, Munjal, Kabeer, Kamdar, Zeal, Kagohara, Luciane T, Jaffee, Elizabeth M, Yarchoan, Mark, Ho, Won Jin
Published in Hepatology (Baltimore, Md.) (01.05.2023)
Published in Hepatology (Baltimore, Md.) (01.05.2023)
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Proteo-metabolomics and patient tumor slice experiments point to amino acid centrality for rewired mitochondria in fibrolamellar carcinoma
Long, Donald, Chan, Marina, Han, Mingqi, Kamdar, Zeal, Ma, Rosanna K., Tsai, Pei-Yin, Francisco, Adam B., Barrow, Joeva, Shackelford, David B., Yarchoan, Mark, McBride, Matthew J., Orre, Lukas M., Vacanti, Nathaniel M., Gujral, Taranjit S., Sethupathy, Praveen
Published in Cell reports. Medicine (21.08.2024)
Published in Cell reports. Medicine (21.08.2024)
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Abstract 3679: DNAJB1-PRKACA fusion in fibrolamellar hepatocellular carcinoma induces glutamine addiction and an immunosuppressive tumor microenvironment
Kamdar, Zeal, Lopez-Vidal, Tamara, Howe, Kathryn, Munjal, Kabeer, Saeed, Ali, Zabransky, Daniel, Shu, Daniel, Longway, Gabriella, Kartalia, Emma, Leatherman, James, Mohan, Aditya, Khare, Pratik, Zhang, Cissy, Le, Anne, Pearce, Erika, Furth, Mark, Baretti, Marina, Leone, Robert, Jaffee, Elizabeth, Yarchoan, Mark
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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