A small molecule HIF-1α stabilizer that accelerates diabetic wound healing
Li, Guodong, Ko, Chung-Nga, Li, Dan, Yang, Chao, Wang, Wanhe, Yang, Guan-Jun, Di Primo, Carmelo, Wong, Vincent Kam Wai, Xiang, Yaozu, Lin, Ligen, Ma, Dik-Lung, Leung, Chung-Hang
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer
Teng, Jin-Feng, Mei, Qi-Bing, Zhou, Xiao-Gang, Tang, Yong, Xiong, Rui, Qiu, Wen-Qiao, Pan, Rong, Law, Betty Yuen-Kwan, Wong, Vincent Kam-Wai, Yu, Chong-Lin, Long, Han-An, Xiao, Xiu-Li, Zhang, Feng, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo
Published in Cancers (13.01.2020)
Published in Cancers (13.01.2020)
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Selective Inhibition of Lysine‐Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple‐Negative Breast Cancer Therapy
Yang, Guan‐Jun, Wang, Wanhe, Mok, Simon Wing Fai, Wu, Chun, Law, Betty Yuen Kwan, Miao, Xiang‐Min, Wu, Ke‐Jia, Zhong, Hai‐Jing, Wong, Chun‐Yuen, Wong, Vincent Kam Wai, Ma, Dik‐Lung, Leung, Chung‐Hang
Published in Angewandte Chemie International Edition (01.10.2018)
Published in Angewandte Chemie International Edition (01.10.2018)
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Journal Article
HM30181A, a potent P-glycoprotein inhibitor, potentiates the absorption and in vivo antitumor efficacy of paclitaxel in an orthotopic brain tumor model
Zeng, Wu, Kwan Law, Betty Yuen, Wai Wong, Vincent Kam, Bik Chan, Denise So, Fai Mok, Simon Wing, Ying Gao, Joyce Jia, Yan Ho, Rebecca Ka, Liang, Xu, Li, Jia Hao, Lee, Ming Tsung, Yoon, Weng Li, Smolinski, Michael P, Nam Lau, Johnson Yiu, Kei Lam, Christopher Wai, Fok, Manson
Published in Cancer biology & medicine (15.11.2020)
Published in Cancer biology & medicine (15.11.2020)
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Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer
Teng, Jin-Feng, Qin, Da-Lian, Mei, Qi-Bing, Qiu, Wen-Qiao, Pan, Rong, Xiong, Rui, Zhao, Ya, Law, Betty Yuen-Kwan, Wong, Vincent Kam-Wai, Tang, Yong, Yu, Chong-Lin, Zhang, Feng, Wu, Jian-Ming, Wu, An-Guo
Published in Pharmacological research (01.09.2019)
Published in Pharmacological research (01.09.2019)
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Matrine Induces Cell Anergy in Human Jurkat T Cells through Modulation of Mitogen-Activated Protein Kinases and Nuclear Factor of Activated T-Cells Signaling with Concomitant Up-Regulation of Anergy-Associated Genes Expression
Li, Ting, Wong, Vincent Kam Wai, Yi, Xiao Qin, Wong, Yuen Fan, Zhou, Hua, Liu, Liang
Published in Biological & pharmaceutical bulletin (01.01.2010)
Published in Biological & pharmaceutical bulletin (01.01.2010)
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Natural products-based polypharmacological modulation of the peripheral immune system for the treatment of neuropsychiatric disorders
Mok, Simon Wing-Fai, Wong, Vincent Kam-Wai, Lo, Hang-Hong, de Seabra Rodrigues Dias, Ivo Ricardo, Leung, Elaine Lai-Han, Law, Betty Yuen-Kwan, Liu, Liang
Published in Pharmacology & therapeutics (Oxford) (01.04.2020)
Published in Pharmacology & therapeutics (Oxford) (01.04.2020)
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Journal Article
Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism
Law, Betty Yuen Kwan, Michelangeli, Francesco, Qu, Yuan Qing, Xu, Su-Wei, Han, Yu, Mok, Simon Wing Fai, Dias, Ivo Ricardo de Seabra Rodrigues, Javed, Masood-ul-Hassan, Chan, Wai-Kit, Xue, Wei-Wei, Yao, Xiao-Jun, Zeng, Wu, Zhang, Hui, Wang, Jing-Rong, Liu, Liang, Wong, Vincent Kam Wai
Published in Scientific reports (27.12.2019)
Published in Scientific reports (27.12.2019)
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Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells
Wu, An-Guo, Wong, Vincent Kam-Wai, Xu, Su-Wei, Chan, Wai-Kit, Ng, Choi-In, Liu, Liang, Law, Betty Yuen-Kwan
Published in International journal of molecular sciences (15.11.2013)
Published in International journal of molecular sciences (15.11.2013)
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Journal Article
Pathogenesis of thromboangiitis obliterans: Gene polymorphism and immunoregulation of human vascular endothelial cells
Sun, Xiao-lei, Law, Betty Yuen-Kwan, de Seabra Rodrigues Dias, Ivo Ricardo, Mok, Simon Wing Fai, He, Yan-zheng, Wong, Vincent Kam-Wai
Published in Atherosclerosis (01.10.2017)
Published in Atherosclerosis (01.10.2017)
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Network Pharmacology Exploration Reveals Anti-Apoptosis as a Common Therapeutic Mechanism for Non-Alcoholic Fatty Liver Disease Treated with Blueberry Leaf Polyphenols
Wang, Cai-Ren, Chen, Hong-Wei, Li, Yan, Zhou, Ming-Yue, Wong, Vincent Kam-Wai, Jiang, Zhi-Hong, Zhang, Wei
Published in Nutrients (13.11.2021)
Published in Nutrients (13.11.2021)
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Journal Article
Bavachin Protects Human Aortic Smooth Muscle Cells Against β -Glycerophosphate-Mediated Vascular Calcification and Apoptosis via Activation of mTOR-Dependent Autophagy and Suppression of β -Catenin Signaling
He, Hu-Qiang, Law, Betty Yuen Kwan, Zhang, Ni, Qiu, Cong-Ling, Qu, Yuan-Qing, Wu, An-Guo, Han, Yu, Song, Qi, Zheng, Wen-Lu, Liu, Yong, He, Yan-Zheng, Wong, Vincent Kam Wai
Published in Frontiers in pharmacology (19.12.2019)
Published in Frontiers in pharmacology (19.12.2019)
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A robust luminescent assay for screening alkyladenine DNA glycosylase inhibitors to overcome DNA repair and temozolomide drug resistance
Song, Ying-Qi, Li, Guo-Dong, Niu, Dou, Chen, Feng, Jing, Shaozhen, Wai Wong, Vincent Kam, Wang, Wanhe, Leung, Chung-Hang
Published in Journal of pharmaceutical analysis (01.05.2023)
Published in Journal of pharmaceutical analysis (01.05.2023)
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The New Application of UHPLC-DAD-TOF/MS in Identification of Inhibitors on β-Amyloid Fibrillation From Scutellaria baicalensis
Yu, Lu, Wu, An-Guo, Wong, Vincent Kam-Wai, Qu, Li-Qun, Zhang, Ni, Qin, Da-Lian, Zeng, Wu, Tang, Bin, Wang, Hui-Miao, Wang, Qiong, Law, Betty Yuen-Kwan
Published in Frontiers in pharmacology (18.03.2019)
Published in Frontiers in pharmacology (18.03.2019)
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Journal Article
AGEs-Induced Calcification and Apoptosis in Human Vascular Smooth Muscle Cells Is Reversed by Inhibition of Autophagy
He, Hu-Qiang, Qu, Yuan-Qing, Kwan Law, Betty Yuen, Qiu, Cong-ling, Han, Yu, Ricardo de Seabra Rodrigues Dias, Ivo, Liu, Yong, Zhang, Jie, Wu, An-Guo, Wu, Cheng-Wen, Fai Mok, Simon Wing, Cheng, Xin, He, Yan-Zheng, Wai Wong, Vincent Kam
Published in Frontiers in pharmacology (20.10.2021)
Published in Frontiers in pharmacology (20.10.2021)
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Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease
Zhou, Xiao-Gang, Qiu, Wen-Qiao, Yu, Lu, Pan, Rong, Teng, Jin-Feng, Sang, Zhi-Pei, Law, Betty Yuen-Kwan, Zhao, Ya, Zhang, Li, Yan, Lu, Tang, Yong, Sun, Xiao-Lei, Wong, Vincent Kam Wai, Yu, Chong-Lin, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo
Published in Inflammation and Regeneration (03.08.2022)
Published in Inflammation and Regeneration (03.08.2022)
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Autophagic effects of Chaihu (dried roots of Bupleurum Chinense DC or Bupleurum scorzoneraefolium WILD)
Law, Betty Yuen-Kwan, Mo, Jing-Fang, Wong, Vincent Kam-Wai
Published in Chinese medicine (11.09.2014)
Published in Chinese medicine (11.09.2014)
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Targeting autophagy as a therapeutic strategy for identification of liganans from Peristrophe japonica in Parkinson's disease
Wu, An-Guo, Pan, Rong, Law, Betty Yuen-Kwan, Qiu, Wen-Qiao, Wu, Jian-Ming, He, Chang-Long, Wong, Vincent Kam-Wai, Yu, Chong-Lin, Zhou, Xiao-Gang, Qin, Da-Lian
Published in Signal transduction and targeted therapy (17.02.2021)
Published in Signal transduction and targeted therapy (17.02.2021)
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Saikosaponin-d, a calcium mobilizing agent, sensitizes chemoresistant ovarian cancer cells to cisplatin-induced apoptosis by facilitating mitochondrial fission and G2/M arrest
Tsuyoshi, Hideaki, Wong, Vincent Kam Wai, Han, Yu, Orisaka, Makoto, Yoshida, Yoshio, Tsang, Benjamin K.
Published in Oncotarget (21.11.2017)
Published in Oncotarget (21.11.2017)
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