Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13
Scherer, Stephanie L., Cain, Matthew D., Kanai, Stanley M., Kaltenbronn, Kevin M., Blumer, Kendall J.
Published in The Journal of biological chemistry (01.06.2017)
Published in The Journal of biological chemistry (01.06.2017)
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Journal Article
GIRK channel modulation by assembly with allosterically regulated RGS proteins
Zhou, Hao, Chisari, Mariangela, Raehal, Kirsten M, Kaltenbronn, Kevin M, Bohn, Laura M, Mennerick, Steven J, Blumer, Kendall J
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2012)
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Journal Article
Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure
Mendelsohn, Michael E, Tang, Mary, Wang, Guang, Lu, Ping, Karas, Richard H, Aronovitz, Mark, Heximer, Scott P, Kaltenbronn, Kevin M, Blumer, Kendall J, Siderovski, David P, Zhu, Yan
Published in Nature medicine (01.12.2003)
Published in Nature medicine (01.12.2003)
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Journal Article
Regulator of G Protein Signaling 2 Deficiency Causes Endothelial Dysfunction and Impaired Endothelium-derived Hyperpolarizing Factor-mediated Relaxation by Dysregulating Gi/o Signaling
Osei-Owusu, Patrick, Sabharwal, Rasna, Kaltenbronn, Kevin M., Rhee, Man-Hee, Chapleau, Mark W., Dietrich, Hans H., Blumer, Kendall J.
Published in The Journal of biological chemistry (06.04.2012)
Published in The Journal of biological chemistry (06.04.2012)
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Journal Article
RGS2 Is a Mediator of Nitric Oxide Action on Blood Pressure and Vasoconstrictor Signaling
Sun, Xiaoguang, Kaltenbronn, Kevin M, Steinberg, Thomas H, Blumer, Kendall J
Published in Molecular pharmacology (01.03.2005)
Published in Molecular pharmacology (01.03.2005)
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Journal Article
A Building Block Approach for the Total Synthesis of YM‐385781
Zhu, Yu, Liu, Siyue, Zigmond, Johnny, Kaltenbronn, Kevin M., Blumer, Kendall J., Moeller, Kevin D.
Published in European journal of organic chemistry (22.05.2023)
Published in European journal of organic chemistry (22.05.2023)
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Journal Article
Targeting primary and metastatic uveal melanoma with a G protein inhibitor
Onken, Michael D., Makepeace, Carol M., Kaltenbronn, Kevin M., Choi, Joelle, Hernandez-Aya, Leonel, Weilbaecher, Katherine N., Piggott, Kisha D., Rao, P. Kumar, Yuede, Carla M., Dixon, Alethia J., Osei-Owusu, Patrick, Cooper, John A., Blumer, Kendall J.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Protein Kinase Signaling Networks Driven by Oncogenic Gq/11 in Uveal Melanoma Identified by Phosphoproteomic and Bioinformatic Analyses
Onken, Michael D., Erdmann-Gilmore, Petra, Zhang, Qiang, Thapa, Kisan, King, Emily, Kaltenbronn, Kevin M., Noda, Sarah E., Makepeace, Carol M., Goldfarb, Dennis, Babur, Özgün, Townsend, R. Reid, Blumer, Kendall J.
Published in Molecular & cellular proteomics (01.11.2023)
Published in Molecular & cellular proteomics (01.11.2023)
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Journal Article
Oncogenic Gq/11 signaling acutely drives and chronically sustains metabolic reprogramming in uveal melanoma
Onken, Michael D., Noda, Sarah E., Kaltenbronn, Kevin M., Frankfater, Cheryl, Makepeace, Carol M., Fettig, Nikki, Piggott, Kisha D., Custer, Philip L., Ippolito, Joseph E., Blumer, Kendall J.
Published in The Journal of biological chemistry (01.01.2022)
Published in The Journal of biological chemistry (01.01.2022)
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Journal Article
Building Chemical Probes Based on the Natural Products YM-254890 and FR900359: Advances toward Scalability
Medcalf, Matthew R., Krueger, Ruby L., Medcalf, Zach T., Rosston, Peter A., Zhu, Yu, Kaltenbronn, Kevin M., Blumer, Kendall J., Moeller, Kevin D.
Published in Synthesis (Stuttgart) (01.01.2023)
Published in Synthesis (Stuttgart) (01.01.2023)
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Journal Article
Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells
Onken, Michael D, Makepeace, Carol M, Kaltenbronn, Kevin M, Kanai, Stanley M, Todd, Tyson D, Wang, Shiqi, Broekelmann, Thomas J, Rao, Prabakar Kumar, Cooper, John A, Blumer, Kendall J
Published in Science signaling (04.09.2018)
Published in Science signaling (04.09.2018)
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Journal Article
Breast Cancer Cell Targeting by Prenylation Inhibitors Elucidated in Living Animals with a Bioluminescence Reporter
CHINAULT, Sharon L, PRIOR, Julie L, KALTENBRONN, Kevin M, PENLY, Anya, WEILBAECHER, Katherine N, PIWNICA-WORMS, David, BLUMER, Kendall J
Published in Clinical cancer research (01.08.2012)
Published in Clinical cancer research (01.08.2012)
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Journal Article
R7BP Augments the Function of RGS7·Gβ5 Complexes by a Plasma Membrane-targeting Mechanism
Drenan, Ryan M., Doupnik, Craig A., Jayaraman, Muralidharan, Buchwalter, Abigail L., Kaltenbronn, Kevin M., Huettner, James E., Linder, Maurine E., Blumer, Kendall J.
Published in The Journal of biological chemistry (22.09.2006)
Published in The Journal of biological chemistry (22.09.2006)
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Journal Article
Genetic ablation of calcium-independent phospholipase A(2)beta causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine
Dietrich, Hans H, Abendschein, Dana R, Moon, Sung Ho, Nayeb-Hashemi, Neema, Mancuso, David J, Jenkins, Christopher M, Kaltenbronn, Kevin M, Blumer, Kendall J, Turk, John, Gross, Richard W
Published in American journal of physiology. Heart and circulatory physiology (01.06.2010)
Published in American journal of physiology. Heart and circulatory physiology (01.06.2010)
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Journal Article
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice
Heximer, Scott P., Knutsen, Russell H., Sun, Xiaoguang, Kaltenbronn, Kevin M., Rhee, Man-Hee, Peng, Ning, Oliveira-dos-Santos, Antonio, Penninger, Josef M., Muslin, Anthony J., Steinberg, Thomas H., Wyss, J. Michael, Mecham, Robert P., Blumer, Kendall J.
Published in The Journal of clinical investigation (15.02.2003)
Published in The Journal of clinical investigation (15.02.2003)
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Journal Article
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice
Heximer, Scott P, Knutsen, Russell H, Sun, Xiaoguang, Kaltenbronn, Kevin M, Rhee, Man-Hee, Peng, Ning, Oliveira-dos-Santos, Antonio, Penninger, Josef M, Muslin, Anthony J, Steinberg, Thomas H, Wyss, J Michael, Mecham, Robert P, Blumer, Kendall J
Published in The Journal of clinical investigation (01.04.2003)
Published in The Journal of clinical investigation (01.04.2003)
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Journal Article
Abstract PR09: Pharmacologic targeting of Gq reveals new pathways in uveal melanoma
Onken, Michael D., Makepeace, Carol M., Kaltenbronn, Kevin M., Kanai, Stanley M., Todd, Tyson D., Wang, Shiqi, Broekelmann, Thomas J., Rao, Prabakar Kumar, Cooper, John A., Blumer, Kendall J.
Published in Cancer research (Chicago, Ill.) (01.10.2020)
Published in Cancer research (Chicago, Ill.) (01.10.2020)
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Journal Article
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice
Heximer, Scott P, Knutsen, Russell H, Sun, Xiaoguang, Kaltenbronn, Kevin M, Rhee, Man-Hee, Peng, Ning, Oliveira-dos-Santos, Antonio, Penninger, Josef M, Muslin, Anthony J, Steinberg, Thomas H, Wyss, J Michael, Mecham, Robert P, Blumer, Kendall J
Published in The Journal of clinical investigation (01.02.2003)
Published in The Journal of clinical investigation (01.02.2003)
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Journal Article
Abstract 4363: Pharmacologic targeting of Gq reveals new pathways in uveal melanoma
Onken, Michael D., Makepeace, Carol M., Wang, Shiqi, Kaltenbronn, Kevin M., Kanai, Stanley M., Broekelmann, Tom J., Cooper, John A., Blumer, Kendall J.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 1764: Targeting nucleotide exchange to inhibit Gq/11 driver mutations in uveal melanoma
Onken, Michael D., Makepeace, Carol M., Kaltenbronn, Kevin M., Kanai, Stanley M., Todd, Tyson D., Wang, Shiqi, Broekelmann, Thomas J., Rao, Prabakar Kumar, Cooper, John A., Blumer, Kendall J.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article