Dulaglutide exerts beneficial anti atherosclerotic effects in ApoE knockout mice with diabetes: the earlier, the better
Sanada, Junpei, Obata, Atsushi, Obata, Yoshiyuki, Fushimi, Yoshiro, Shimoda, Masashi, Kohara, Kenji, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Published in Scientific reports (14.01.2021)
Published in Scientific reports (14.01.2021)
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Comparison of the effects of three kinds of glucose‐lowering drugs on non‐alcoholic fatty liver disease in patients with type 2 diabetes: A randomized, open‐label, three‐arm, active control study
Kinoshita, Tomoe, Shimoda, Masashi, Nakashima, Koji, Fushimi, Yoshiro, Hirata, Yurie, Tanabe, Akihito, Tatsumi, Fuminori, Hirukawa, Hidenori, Sanada, Junpei, Kohara, Kenji, Irie, Shintaro, Kimura, Tomohiko, Nakamura, Yoshiko, Nishioka, Momoyo, Obata, Atsushi, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Published in Journal of diabetes investigation (01.11.2020)
Published in Journal of diabetes investigation (01.11.2020)
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Early combination therapy of empagliflozin and linagliptin exerts beneficial effects on pancreatic β cells in diabetic db/db mice
Fushimi, Yoshiro, Obata, Atsushi, Sanada, Junpei, Nogami, Yuka, Ikeda, Tomoko, Yamasaki, Yuki, Obata, Yoshiyuki, Shimoda, Masashi, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Published in Scientific reports (09.08.2021)
Published in Scientific reports (09.08.2021)
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Imeglimin exerts favorable effects on pancreatic β-cells by improving morphology in mitochondria and increasing the number of insulin granules
Sanada, Junpei, Obata, Atsushi, Fushimi, Yoshiro, Kimura, Tomohiko, Shimoda, Masashi, Ikeda, Tomoko, Nogami, Yuka, Obata, Yoshiyuki, Yamasaki, Yuki, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Published in Scientific reports (02.08.2022)
Published in Scientific reports (02.08.2022)
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Unexpected Pleiotropic Effects of SGLT2 Inhibitors: Pearls and Pitfalls of This Novel Antidiabetic Class
Kaneto, Hideaki, Obata, Atsushi, Kimura, Tomohiko, Shimoda, Masashi, Kinoshita, Tomoe, Matsuoka, Taka-Aki, Kaku, Kohei
Published in International journal of molecular sciences (17.03.2021)
Published in International journal of molecular sciences (17.03.2021)
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GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
Shigeto, Makoto, Ramracheya, Reshma, Tarasov, Andrei I, Cha, Chae Young, Chibalina, Margarita V, Hastoy, Benoit, Philippaert, Koenraad, Reinbothe, Thomas, Rorsman, Nils, Salehi, Albert, Sones, William R, Vergari, Elisa, Weston, Cathryn, Gorelik, Julia, Katsura, Masashi, Nikolaev, Viacheslav O, Vennekens, Rudi, Zaccolo, Manuela, Galione, Antony, Johnson, Paul R V, Kaku, Kohei, Ladds, Graham, Rorsman, Patrik
Published in The Journal of clinical investigation (01.12.2015)
Published in The Journal of clinical investigation (01.12.2015)
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Efficacy and safety of once‐weekly semaglutide in Japanese individuals with type 2 diabetes by baseline age and body mass index
Yabe, Daisuke, Yamada, Yuichiro, Kaku, Kohei, Nishida, Tomoyuki, Sato, Toshihiro, Seino, Yutaka
Published in Journal of diabetes investigation (01.07.2022)
Published in Journal of diabetes investigation (01.07.2022)
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Efficacy, safety and tolerability of imeglimin in patients with type 2 diabetes mellitus: A meta‐analysis of randomized controlled trials
Hagi, Katsuhiko, Nitta, Masahiro, Watada, Hirotaka, Kaku, Kohei, Ueki, Kohjiro
Published in Journal of diabetes investigation (01.11.2023)
Published in Journal of diabetes investigation (01.11.2023)
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Effect of patient characteristics on the efficacy and safety of imeglimin monotherapy in Japanese patients with type 2 diabetes mellitus: A post‐hoc analysis of two randomized, placebo‐controlled trials
Hagi, Katsuhiko, Kochi, Kenji, Watada, Hirotaka, Kaku, Kohei, Ueki, Kohjiro
Published in Journal of diabetes investigation (01.09.2023)
Published in Journal of diabetes investigation (01.09.2023)
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Favorable Effects of GLP-1 Receptor Agonist against Pancreatic β-Cell Glucose Toxicity and the Development of Arteriosclerosis: “The Earlier, the Better” in Therapy with Incretin-Based Medicine
Kaneto, Hideaki, Kimura, Tomohiko, Shimoda, Masashi, Obata, Atsushi, Sanada, Junpei, Fushimi, Yoshiro, Nakanishi, Shuhei, Mune, Tomoatsu, Kaku, Kohei
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Case Report: Markedly Long-Term Preservation of Pancreatic β-Cell Function in a Subject With Elderly Onset of Type 1 Diabetes Mellitus Showing High-Titer Autoimmune Antibodies for Over 4 Years
Shigemoto, Ryo, Anno, Takatoshi, Kawasaki, Fumiko, Kaku, Kohei, Kaneto, Hideaki
Published in Frontiers in immunology (25.11.2021)
Published in Frontiers in immunology (25.11.2021)
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Pancreatic alpha cells in diabetic rats express active GLP-1 receptor: Endosomal co-localization of GLP-1/GLP-1R complex functioning through intra-islet paracrine mechanism
Nakashima, Koji, Kaneto, Hideaki, Shimoda, Masashi, Kimura, Tomohiko, Kaku, Kohei
Published in Scientific reports (27.02.2018)
Published in Scientific reports (27.02.2018)
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Influence of Nutritional Guidance/Consulting on Glycemic Control during the Coronavirus Disease 2019 Pandemic in Patients with Type 2 Diabetes Mellitus
Iwamoto, Yuichiro, Nakanishi, Shuhei, Iwamoto, Hideyuki, Sanada, Junpei, Fushimi, Yoshiro, Katakura, Yukino, Kimura, Tomohiko, Tatsumi, Fuminori, Shimoda, Masashi, Mune, Tomoatsu, Kaku, Kohei, Kaneto, Hideaki
Published in Internal Medicine (15.03.2023)
Published in Internal Medicine (15.03.2023)
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Long‐term (52‐week) efficacy and safety of ipragliflozin add‐on therapy to insulin in Japanese patients with type 1 diabetes mellitus: An uncontrolled, open‐label extension of a phase III study
Kaku, Kohei, Isaka, Hiroyuki, Sakatani, Taishi, Toyoshima, Junko
Published in Journal of diabetes investigation (01.05.2020)
Published in Journal of diabetes investigation (01.05.2020)
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