A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma
Kakiuchi-Kiyota, Satoko, Ross, Thorsten, Wallweber, Heidi Ackerly, Kiefer, James R., Schutten, Melissa M., Adedeji, Adeyemi O., Cai, Hao, Hendricks, Robert, Cohen, Sivan, Myneni, Srividya, Liu, Luna, Fullerton, Aaron, Corr, Nicholas, Yu, Lanlan, de Almeida Nagata, Denise, Zhong, Shelly, Leong, Steven R., Li, Ji, Nakamura, Rin, Sumiyoshi, Teiko, Li, Jinze, Ovacik, Ayse Meric, Zheng, Bing, Dillon, Mike, Spiess, Christoph, Wingert, Susanne, Rajkovic, Erich, Ellwanger, Kristina, Reusch, Uwe, Polson, Andrew G.
Published in Leukemia (01.04.2022)
Published in Leukemia (01.04.2022)
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Journal Article
Cytotoxicity and gene expression changes induced by inorganic and organic trivalent arsenicals in human cells
Dodmane, Puttappa R, Arnold, Lora L, Kakiuchi-Kiyota, Satoko, Qiu, Fang, Liu, Xiangde, Rennard, Stephen I, Cohen, Samuel M
Published in Toxicology (Amsterdam) (04.10.2013)
Published in Toxicology (Amsterdam) (04.10.2013)
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Comparison of hepatic transcription profiles of locked ribonucleic acid antisense oligonucleotides: evidence of distinct pathways contributing to non-target mediated toxicity in mice
Kakiuchi-Kiyota, Satoko, Koza-Taylor, Petra H, Mantena, Srinivasa R, Nelms, Linda F, Enayetallah, Ahmed E, Hollingshead, Brett D, Burdick, Andrew D, Reed, Lori A, Warneke, James A, Whiteley, Lawrence O, Ryan, Anne M, Mathialagan, Nagappan
Published in Toxicological sciences (01.03.2014)
Published in Toxicological sciences (01.03.2014)
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Journal Article
Effects of Pioglitazone, a Peroxisome Proliferator-Activated Receptor Gamma Agonist, on the Urine and Urothelium of the Rat
Suzuki, Shugo, Arnold, Lora L., Pennington, Karen L., Kakiuchi-Kiyota, Satoko, Wei, Min, Wanibuchi, Hideki, Cohen, Samuel M.
Published in Toxicological sciences (01.02.2010)
Published in Toxicological sciences (01.02.2010)
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Journal Article
Effect of sodium arsenite dose administered in the drinking water on the urinary bladder epithelium of female arsenic (+3 oxidation state) methyltransferase knockout mice
Yokohira, Masanao, Arnold, Lora L, Pennington, Karen L, Suzuki, Shugo, Kakiuchi-Kiyota, Satoko, Herbin-Davis, Karen, Thomas, David J, Cohen, Samuel M
Published in Toxicological sciences (01.06.2011)
Published in Toxicological sciences (01.06.2011)
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Journal Article
Severe systemic toxicity and urinary bladder cytotoxicity and regenerative hyperplasia induced by arsenite in arsenic (+ 3 oxidation state) methyltransferase knockout mice. A preliminary report
Yokohira, Masanao, Arnold, Lora L., Pennington, Karen L., Suzuki, Shugo, Kakiuchi-Kiyota, Satoko, Herbin-Davis, Karen, Thomas, David J., Cohen, Samuel M.
Published in Toxicology and applied pharmacology (01.07.2010)
Published in Toxicology and applied pharmacology (01.07.2010)
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Journal Article
Evaluation of expression profiles of hematopoietic stem cell, endothelial cell, and myeloid cell antigens in spontaneous and chemically induced hemangiosarcomas and hemangiomas in mice
Kakiuchi-Kiyota, Satoko, Crabbs, Torrie A, Arnold, Lora L, Pennington, Karen L, Cook, Jon C, Malarkey, David E, Cohen, Samuel M
Published in Toxicologic pathology (01.07.2013)
Published in Toxicologic pathology (01.07.2013)
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Journal Article
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel
Liu, Chang, Reese, Rebecca, Vu, Simon, Rougé, Lionel, Shields, Shannon D., Kakiuchi-Kiyota, Satoko, Chen, Huifen, Johnson, Kevin, Shi, Yu Patrick, Chernov-Rogan, Tania, Greiner, Demi Maria Zabala, Kohli, Pawan Bir, Hackos, David, Brillantes, Bobby, Tam, Christine, Li, Tianbo, Wang, Jianyong, Safina, Brian, Magnuson, Steve, Volgraf, Matthew, Payandeh, Jian, Zheng, Jie, Rohou, Alexis, Chen, Jun
Published in Neuron (Cambridge, Mass.) (20.01.2021)
Published in Neuron (Cambridge, Mass.) (20.01.2021)
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Journal Article
Computational analysis of kinase inhibitor selectivity using structural knowledge
Lo, Yu-Chen, Liu, Tianyun, Morrissey, Kari M, Kakiuchi-Kiyota, Satoko, Johnson, Adam R, Broccatelli, Fabio, Zhong, Yu, Joshi, Amita, Altman, Russ B
Published in Bioinformatics (15.01.2019)
Published in Bioinformatics (15.01.2019)
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Journal Article
Nonclinical Pharmacokinetics, Pharmacodynamics, and Translational Model of RO7297089, A Novel Anti-BCMA/CD16A Bispecific Tetravalent Antibody for the Treatment of Multiple Myeloma
Cai, Hao, Kakiuchi-Kiyota, Satoko, Hendricks, Robert, Zhong, Shelly, Liu, Luna, Adedeji, Adeyemi O., Chan, Pamela, Schutten, Melissa M., Kamath, Amrita V., Ovacik, Meric A.
Published in The AAPS journal (20.09.2022)
Published in The AAPS journal (20.09.2022)
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Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease
Terrett, Jack A., Ly, Justin Q., Katavolos, Paula, Hasselgren, Catrin, Laing, Steven, Zhong, Fiona, Villemure, Elisia, Déry, Martin, Larouche-Gauthier, Robin, Chen, Huifen, Shore, Daniel G., Lee, Wyne P., Suto, Eric, Johnson, Kevin, Brooks, Marjory, Stablein, Alyssa, Beaumier, Francis, Constantineau-Forget, Léa, Grand-Maître, Chantal, Lépissier, Luce, Ciblat, Stéphane, Sturino, Claudio, Chen, Yong, Hu, Baihua, Elstrott, Justin, Gandham, Vineela, Joseph, Victory, Booler, Helen, Cain, Gary, Chou, Carolina, Fullerton, Aaron, Lepherd, Michelle, Stainton, Shannon, Torres, Elizabeth, Urban, Konnie, Yu, Lanlan, Zhong, Yu, Bao, Linda, Chou, Kang-Jye, Lin, Jessica, Zhang, Wei, La, Hank, Liu, Liling, Mulder, Teresa, Chen, Jun, Chernov-Rogan, Tania, Johnson, Adam R., Hackos, David H., Leahey, Rebecca, Shields, Shannon D., Balestrini, Alessia, Riol-Blanco, Lorena, Safina, Brian S., Volgraf, Matthew, Magnuson, Steven, Kakiuchi-Kiyota, Satoko
Published in Journal of medicinal chemistry (14.03.2024)
Published in Journal of medicinal chemistry (14.03.2024)
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Journal Article
Abstract 4556: Preclinical pharmacology and safety of RO7297089, a novel anti-BCMA/CD16a bispecific antibody for the treatment of multiple myeloma
Kakiuchi-Kiyota, Satoko, Schutten, Melissa M., Adedeji, Adeyemi O., Cai, Hao, Hendricks, Robert, Liu, Luna, Cohen, Sivan, Fullerton, Aaron M., Corr, Nicholas, Yu, Lanlan, Nagata, Denise de Almeida, Zhong, Shelly, Dillon, Michael, Spiess, Christoph, Leong, Steve R., Zheng, Bing, Wingert, Susanne, Reusch, Uwe, Knackmuss, Stefan, Ross, Thorsten, Polson, Andrew, Ovacik, Ayse M.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1
Tellis, John C, Wei, BinQing, Siu, Michael, An, Le, Chan, Grace Kayan, Chen, Yong, Du, Xiangnan, Gazzard, Lewis, Hu, Baihua, Kiefer, James, Kakiuchi-Kiyota, Satoko, Lainchbury, Michael, Linehan, Jonathan L, Luo, Xifeng, Malhotra, Sushant, Mendonca, Rohan, Pang, Jodie, Ran, Yinqing, Sethuraman, Vijay, Seward, Eileen, Sneeringer, Chris, Su, Dian, Wang, Weiru, Wu, Ping, Moffat, John G, Heffron, Timothy P, Choo, Edna F, Chan, Bryan K
Published in ACS medicinal chemistry letters (12.09.2024)
Published in ACS medicinal chemistry letters (12.09.2024)
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Journal Article
Optimization of a Novel DEL Hit That Binds in the Cbl‑b SH2 Domain and Blocks Substrate Binding
Liang, Jun, Lambrecht, Michael J., Arenzana, Teresita L., Aubert-Nicol, Samuel, Bao, Linda, Broccatelli, Fabio, Cai, Jianping, Eidenschenk, Celine, Everett, Christine, Garner, Thomas, Gruber, Felix, Haghshenas, Pouyan, Huestis, Malcolm P., Hsu, Peter L., Kou, Ponien, Jakalian, Araz, Larouche-Gauthier, Robin, Leclerc, Jean-Philippe, Leung, Dennis H., Martin, Aaron, Murray, Jeremy, Prangley, Madeleine, Rutz, Sascha, Kakiuchi-Kiyota, Satoko, Satz, Alexander Lee, Skelton, Nicholas J., Steffek, Micah, Stoffler, Daniel, Sudhamsu, Jawahar, Tan, Sophia, Wang, Jian, Wang, Shouliang, Wang, Qiuyue, Wendorff, Timothy J., Wichert, Moreno, Yadav, Arun, Yu, Christine, Wang, Xiaojing
Published in ACS medicinal chemistry letters (13.06.2024)
Published in ACS medicinal chemistry letters (13.06.2024)
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Journal Article
Urinary crystal formation and urothelial effects of pyroxasulfone administered to male rats
Kyoya, Takahiro, Arnold, Lora L., Pennington, Karen L., Kakiuchi-Kiyota, Satoko, Terada, Megumi, Abe, Koichi, Cohen, Samuel M.
Published in Toxicology mechanisms and methods (21.11.2020)
Published in Toxicology mechanisms and methods (21.11.2020)
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