Biallelic loss of BCMA as a resistance mechanism to CAR T cell therapy in a patient with multiple myeloma
Samur, Mehmet Kemal, Fulciniti, Mariateresa, Aktas Samur, Anil, Bazarbachi, Abdul Hamid, Tai, Yu-Tzu, Prabhala, Rao, Alonso, Alejandro, Sperling, Adam S., Campbell, Timothy, Petrocca, Fabio, Hege, Kristen, Kaiser, Shari, Loiseau, Hervé Avet, Anderson, Kenneth C., Munshi, Nikhil C.
Published in Nature communications (08.02.2021)
Published in Nature communications (08.02.2021)
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Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model
Rosenberger, Carrie M, Podyminogin, Rebecca L, Askovich, Peter S, Navarro, Garnet, Kaiser, Shari M, Sanders, Catherine J, McClaren, Jennifer L, Tam, Vincent C, Dash, Pradyot, Noonan, Jhoanna G, Jones, Bart G, Surman, Sherri L, Peschon, Jacques J, Diercks, Alan H, Hurwitz, Julia L, Doherty, Peter C, Thomas, Paul G, Aderem, Alan
Published in Journal of general virology (01.02.2014)
Published in Journal of general virology (01.02.2014)
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Time-Dependent Prognostic Value of Serological and Measurable Residual Disease Assessments after Idecabtagene Vicleucel
Paiva, Bruno, Manrique, Irene, Rytlewski, Julie, Campbell, Timothy, Kazanecki, Christian C, Martin, Nathan, Anderson, Jr, Larry D, Berdeja, Jesús G, Lonial, Sagar, Raje, Noopur S, Lin, Yi, Moreau, Philippe, San-Miguel, Jesús F, Munshi, Nikhil C, Kaiser, Shari M
Published in Blood cancer discovery (01.09.2023)
Published in Blood cancer discovery (01.09.2023)
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A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm
Aderem, Alan, Adkins, Joshua N, Ansong, Charles, Galagan, James, Kaiser, Shari, Korth, Marcus J, Law, G Lynn, McDermott, Jason G, Proll, Sean C, Rosenberger, Carrie, Schoolnik, Gary, Katze, Michael G
Published in mBio (01.03.2011)
Published in mBio (01.03.2011)
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P801: BASELINE AND EARLY POST‐INFUSION BIOMARKERS ASSOCIATED WITH OPTIMAL RESPONSE TO IDECABTAGENE VICLEUCEL (IDE‐CEL) IN THE KARMMA‐3 STUDY OF TRIPLE‐CLASS–EXPOSED RELAPSED AND REFRACTORY MULTIPLE MYELOMA
Piasecki, Julia, Desai, Keyur, Courtney, Carolyn, Thompson, Ethan, Pratt, James, Raje, Noopur, Patel, Krina, Raab, Marc S., Cook, Mark, Simonsen, Katy, Popa Mckiver, Mihaela, Kaiser, Shari, Martin, Nathan
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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S188: CAR‐T CELLS SHAPE THE IMMUNOLOGICAL POTENTIAL OF THE TUMOR MICROENVIRONMENT
Frede, Julia, Poller, Julia, Shi, Kayleen, Stuart, Hannah, Sotoudeh, Noori, Lim, Klothilda, Wiggers, Caroline, Waldschmidt, Johannes, Dimitrova, Valeriya, Montanaro, Anna, Cho, Eugene, Vijaykumar, Tushara, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth, Martin, Nathan, Kaiser, Shari, Raab, Marc‐Steffen, Knoechel, Birgit, Lohr, Jens
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Controlling Lentiviruses: Single Amino Acid Changes Can Determine Specificity
Kaiser, Shari M, Emerman, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2004)
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Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma
Munshi, Nikhil C, Anderson, Larry D, Shah, Nina, Madduri, Deepu, Berdeja, Jesús, Lonial, Sagar, Raje, Noopur, Lin, Yi, Siegel, David, Oriol, Albert, Moreau, Philippe, Yakoub-Agha, Ibrahim, Delforge, Michel, Cavo, Michele, Einsele, Hermann, Goldschmidt, Hartmut, Weisel, Katja, Rambaldi, Alessandro, Reece, Donna, Petrocca, Fabio, Massaro, Monica, Connarn, Jamie N, Kaiser, Shari, Patel, Payal, Huang, Liping, Campbell, Timothy B, Hege, Kristen, San-Miguel, Jesús
Published in The New England journal of medicine (25.02.2021)
Published in The New England journal of medicine (25.02.2021)
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Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma
Da Vià, Matteo C., Dietrich, Oliver, Truger, Marietta, Arampatzi, Panagiota, Duell, Johannes, Heidemeier, Anke, Zhou, Xiang, Danhof, Sophia, Kraus, Sabrina, Chatterjee, Manik, Meggendorfer, Manja, Twardziok, Sven, Goebeler, Maria-Elisabeth, Topp, Max S., Hudecek, Michael, Prommersberger, Sabrina, Hege, Kristen, Kaiser, Shari, Fuhr, Viktoria, Weinhold, Niels, Rosenwald, Andreas, Erhard, Florian, Haferlach, Claudia, Einsele, Hermann, Kortüm, K. Martin, Saliba, Antoine-Emmanuel, Rasche, Leo
Published in Nature medicine (01.04.2021)
Published in Nature medicine (01.04.2021)
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Differences in Single Cells between BCMA-Targeting CAR T-Cell Therapy Responders and Non-Responders Reveals Initial Resistance and Acquired Resistance Are Driven By Different Factors
Samur, Mehmet K., Martin, Nathan, Thompson, Ethan, Fulciniti, Mariateresa, Aktas-Samur, Anil, Kaiser, Shari, Munshi, Nikhil C
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Tumor-intrinsic features associated with progression-free survival (PFS) in patients (pts) with relapsed and refractory multiple myeloma (RRMM) treated with idecabtagene vicleucel (ide-cel)
Stong, Nicholas, Thompson, Ethan, Xu, Amy, Rytlewski, Julie, Amzallag, Arnaud, Campbell, Timothy Brandon, Jagannath, Sundar, Munshi, Nikhil C., Piasecki, Julia, Basudhar, Debashree, Ortiz Estevez, Maria, Kaiser, Shari, Flynt, Erin, Martin, Nathan
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Baseline and early post-infusion biomarkers associated with optimal response to idecabtagene vicleucel (ide-cel) in the KarMMa-3 study of triple-class–exposed (TCE) relapsed and refractory multiple myeloma (RRMM)
Piasecki, Julia, Desai, Keyur, Courtney, Carolyn, Thompson, Ethan, Pratt, Jim, Raje, Noopur S., Patel, Krina K., Raab, Marc S., Cook, Mark, Simonsen, Katy L., Popa McKiver, Mihaela, Kaiser, Shari, Martin, Nathan
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Nivolumab-Based Salvage Therapy to Restore T Cell Fitness in Penta-Refractory Multiple Myeloma with Relapse to Anti-BCMA CAR T Cell Therapy
Waldschmidt, Johannes M., Arora, Sankalp, Vijaykumar, Tushara, Sotudeh, Noori, Anand, Praveen, Stuart, Hannah, Frede, Julia, Campbell, Tim, Kaiser, Shari M., Lamba, Manisha, Munshi, Nikhil C, Anderson, Kenneth C., Yee, Andrew J., Knoechel, Birgit, Lohr, Jens G., Raje, Noopur
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Early and Sustained Undetectable Measurable Residual Disease (MRD) after Idecabtagene Vicleucel (ide-cel) Defines a Subset of Multiple Myeloma (MM) Patients in Karmma Achieving Prolonged Survival
Paiva, Bruno, Manrique, Irene, Rytlewski, Julie A, Campbell, Timothy B., Kazanecki, Christian, Martin, Nathan, Kaiser, Shari M., Anderson, Larry D., Berdeja, Jesus, Lonial, Sagar, Raje, Noopur, Lin, Yi, Moreau, Philippe, San-Miguel, Jesús, Munshi, Nikhil C
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Biallelic Loss of BCMA Triggers Resistance to Anti-BCMA CAR T Cell Therapy in Multiple Myeloma
Samur, Mehmet K., Fulciniti, Mariateresa, Aktas-Samur, Anil, Bazarbachi, Abdul Hamid, Tai, Yu-Tzu, Campbell, Timothy B., Petrocca, Fabio, Hege, Kristen, Kaiser, Shari, Anderson, Kenneth, Munshi, Nikhil C.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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