Novel LRR-ROC Motif That Links the N- and C-terminal Domains in LRRK2 Undergoes an Order–Disorder Transition Upon Activation
Weng, Jui-Hung, Trilling, Chiara R., Kaila Sharma, Pallavi, Störmer, Eliza, Wu, Jian, Herberg, Friedrich W., Taylor, Susan S.
Published in Journal of molecular biology (15.06.2023)
Published in Journal of molecular biology (15.06.2023)
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Journal Article
Capturing the domain crosstalk in full length LRRK2 and LRRK2RCKW
Störmer, Eliza, Weng, Jui-Hung, Wu, Jian, Bertinetti, Daniela, Kaila Sharma, Pallavi, Ma, Wen, Herberg, Friedrich W, Taylor, Susan
Published in Biochemical journal (22.05.2023)
Published in Biochemical journal (22.05.2023)
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LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains
Weng, Jui-Hung, Aoto, Phillip C, Lorenz, Robin, Wu, Jian, Schmidt, Sven H, Manschwetus, Jascha T, Kaila-Sharma, Pallavi, Silletti, Steve, Mathea, Sebastian, Chatterjee, Deep, Knapp, Stefan, Herberg, Friedrich W, Taylor, Susan S
Published in PLoS biology (22.02.2022)
Published in PLoS biology (22.02.2022)
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RedOx regulation of LRRK2 kinase activity by active site cysteines
Trilling, Chiara R., Weng, Jui-Hung, Sharma, Pallavi Kaila, Nolte, Viktoria, Wu, Jian, Ma, Wen, Boassa, Daniela, Taylor, Susan S., Herberg, Friedrich W.
Published in NPJ Parkinson's Disease (03.04.2024)
Published in NPJ Parkinson's Disease (03.04.2024)
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Corrigendum to “Novel LRR-ROC Motif That Links the N- and C-terminal Domains in LRRK2 Undergoes an Order–Disorder Transition Upon Activation” [J. Mol. Biol. 435(12) (2023) 1–17]
Weng, Jui-Hung, Trilling, Chiara R., Kaila Sharma, Pallavi, Störmer, Eliza, Wu, Jian, Herberg, Friedrich W., Taylor, Susan S.
Published in Journal of molecular biology (15.03.2024)
Published in Journal of molecular biology (15.03.2024)
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Journal Article
Capturing Differences in the Regulation of LRRK2 Dynamics and Conformational States by Small Molecule Kinase Inhibitors
Weng, Jui-Hung, Ma, Wen, Wu, Jian, Sharma, Pallavi Kaila, Silletti, Steve, McCammon, J. Andrew, Taylor, Susan
Published in ACS chemical biology (21.04.2023)
Published in ACS chemical biology (21.04.2023)
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Role of the LRRK2 C-terminal tail in domain crosstalk
Kaila Sharma, Pallavi, Weng, Jui-Hung, Manschwetus, Jascha Tobias, Wu, Jian, Ma, Wen, Herberg, Friedrich W, Taylor, Susan
Published in Biochemical journal (02.02.2024)
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Published in Biochemical journal (02.02.2024)
Journal Article
Two helices control the dynamic crosstalk between the catalytic domains of LRRK2
Jui-Hung Weng, Aoto, Phillop C, Lorenz, Robin, Wu, Jian, Schmidt, Sven H, Manschwetus, Jascha T, Kaila-Sharma, Pallavi, Mathea, Sebastian, Knapp, Stefan, Herberg, Friedrich W, Taylor, Susan S
Published in bioRxiv (29.09.2021)
Published in bioRxiv (29.09.2021)
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