The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status
Guo, Yan-Rong, Cao, Qing-Dong, Hong, Zhong-Si, Tan, Yuan-Yang, Chen, Shou-Deng, Jin, Hong-Jun, Tan, Kai-Sen, Wang, De-Yun, Yan, Yan
Published in Military medical research (13.03.2020)
Published in Military medical research (13.03.2020)
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Journal Article
Proteomics profiling of epithelium-derived exosomes from nasal polyps revealed signaling functions affecting cellular proliferation
Zhou, Min, Tan, Kai Sen, Guan, Wei-jie, Jiang, Li-jie, Deng, Jie, Gao, Wen-xiang, Lee, Yew Mun, Xu, Zhao-feng, Luo, Xin, Liu, Chen, Shi, Jian-bo, Lai, Yinyan
Published in Respiratory medicine (01.02.2020)
Published in Respiratory medicine (01.02.2020)
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Journal Article
CD151, a novel host factor of nuclear export signaling in influenza virus infection
Qiao, Yongkang, Yan, Yan, Tan, Kai Sen, Tan, Sheryl S.L., Seet, Ju Ee, Arumugam, Thiruma Valavan, Chow, Vincent T.K., Wang, De Yun, Tran, Thai
Published in Journal of allergy and clinical immunology (01.05.2018)
Published in Journal of allergy and clinical immunology (01.05.2018)
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Journal Article
SARS-CoV-2 Omicron variant shedding during respiratory activities
Tan, Kai Sen, Ong, Sean Wei Xiang, Koh, Ming Hui, Tay, Douglas Jie Wen, Aw, Daryl Zheng Hao, Nah, Yi Wei, Abdullah, Mohammed Ridzwan Bin, Coleman, Kristen K., Milton, Donald K., Chu, Justin Jang Hann, Chow, Vincent T.K., Tambyah, Paul Anantharajah, Tham, Kwok Wai
Published in International journal of infectious diseases (01.06.2023)
Published in International journal of infectious diseases (01.06.2023)
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Journal Article
Generation of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host-pathogen interactions in the bat airway epithelium
Chan, Louisa L.Y., Gamage, Akshamal M., Tan, Chee Wah, Tan, Kai Sen, Liu, Jing, Tay, Douglas Jie Wen, Foo, Randy Jee Hiang, Rénia, Laurent, Wang, De Yun, Wang, Lin-Fa
Published in Emerging microbes & infections (01.12.2023)
Published in Emerging microbes & infections (01.12.2023)
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Journal Article
Absence or mislocalization of DNAH5 is a characteristic marker for motile ciliary abnormality in nasal polyps
Qiu, Qianhui, Peng, Yang, Zhu, Zhenchao, Chen, Zhuo, Zhang, Chi, Ong, Hsiao Hui, Tan, Kai Sen, Hong, Haiyu, Yan, Yan, Huang, Haoqi, Liu, Jing, Li, Xianqing, Nam, H N, Dung, N T N, Shi, Li, Yang, Qintai, Bingle, Colin D, Wang, De-Yun
Published in The Laryngoscope (01.03.2018)
Published in The Laryngoscope (01.03.2018)
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Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures
Tan, Kai Sen, Yan, Yan, Koh, Wai Ling Hiromi, Li, Liang, Choi, Hyungwon, Tran, Thai, Sugrue, Richard, Wang, De Yun, Chow, Vincent T
Published in Frontiers in microbiology (14.11.2018)
Published in Frontiers in microbiology (14.11.2018)
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Journal Article
Downregulation and Aberrant Localization of Forkhead Box J1 in Allergic Nasal Mucosa
Peng, Yang, Chen, Zhuo, Guan, Wei-Jie, Zhu, Zhenchao, Tan, Kai Sen, Hong, Haiyu, Zi, Xiaoxue, Zeng, Jie, Li, Yixuan, Ong, Yew Kwang, Thong, Mark, Shi, Li, Yang, Qintai, Qiu, Qianhui, Wang, De-Yun
Published in International archives of allergy and immunology (01.01.2018)
Published in International archives of allergy and immunology (01.01.2018)
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Journal Article
Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia
Robinson, Kim S, Teo, Daniel Eng Thiam, Tan, Kai Sen, Toh, Gee Ann, Ong, Hsiao Hui, Lim, Chrissie Kaishi, Lay, Kenneth, Au, Bijin Veonice, Lew, Tian Sheng, Chu, Justin Jang Hann, Chow, Vincent Tak Kwong, Wang, De Yun, Zhong, Franklin L, Reversade, Bruno
Published in Science (American Association for the Advancement of Science) (04.12.2020)
Published in Science (American Association for the Advancement of Science) (04.12.2020)
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Journal Article
Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles
Gamage, Akshamal M, Tan, Kai Sen, Chan, Wharton O Y, Liu, Jing, Tan, Chee Wah, Ong, Yew Kwang, Thong, Mark, Andiappan, Anand K, Anderson, Danielle E, Wang, De Yun, Wang, Lin-Fa
Published in PLoS pathogens (01.12.2020)
Published in PLoS pathogens (01.12.2020)
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Journal Article
Whole-transcriptome sequencing reveals heightened inflammation and defective host defence responses in chronic rhinosinusitis with nasal polyps
Peng, Yang, Zi, Xiao-Xue, Tian, Teng-Fei, Lee, Bernett, Lum, Josephine, Tang, See Aik, Tan, Kai Sen, Qiu, Qian-Hui, Ye, Jing, Shi, Li, Guan, Wei-Jie, Andiappan, Anand Kumar, Wang, De Yun
Published in The European respiratory journal (01.11.2019)
Published in The European respiratory journal (01.11.2019)
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Journal Article
In Vitro Model of Fully Differentiated Human Nasal Epithelial Cells Infected With Rhinovirus Reveals Epithelium-Initiated Immune Responses
Tan, Kai Sen, Ong, Hsiao Hui, Yan, Yan, Liu, Jing, Li, Chunwei, Ong, Yew Kwang, Thong, Kim Thye, Choi, Hyung Won, Wang, De-Yun, Chow, Vincent T
Published in The Journal of infectious diseases (05.03.2018)
Published in The Journal of infectious diseases (05.03.2018)
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Journal Article
Hypoxia‐induced factor‐1α induces NLRP3 expression by M1 macrophages in noneosinophilic chronic rhinosinusitis with nasal polyps
Zhong, Bing, Du, Jintao, Liu, Feng, Liu, Yafeng, Liu, Shixi, Zhang, Jie, Lin, Ping, Zhou, Jiao, Liu, Jing, Ong, Hsiao Hui, Tan, Kai Sen, Wang, Deyun, Ba, Luo
Published in Allergy (Copenhagen) (01.02.2021)
Published in Allergy (Copenhagen) (01.02.2021)
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Journal Article
MicroRNA-146a induction during influenza H3N2 virus infection targets and regulates TRAF6 levels in human nasal epithelial cells (hNECs)
Deng, Yuqin, Yan, Yan, Tan, Kai Sen, Liu, Jing, Chow, Vincent T., Tao, Ze-Zhang, Wang, De-Yun
Published in Experimental cell research (15.03.2017)
Published in Experimental cell research (15.03.2017)
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Journal Article
Tetraspanins: Host Factors in Viral Infections
New, ChihSheng, Lee, Zhao-Yong, Tan, Kai Sen, Wong, Amanda Huee-Ping, Wang, De Yun, Tran, Thai
Published in International journal of molecular sciences (01.11.2021)
Published in International journal of molecular sciences (01.11.2021)
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Journal Article
Neisseria species as pathobionts in bronchiectasis
Li, Liang, Mac Aogáin, Micheál, Xu, Tengfei, Jaggi, Tavleen Kaur, Chan, Louisa L.Y., Qu, Jing, Wei, Lan, Liao, Shumin, Cheng, Hong Sheng, Keir, Holly R., Dicker, Alison J., Tan, Kai Sen, De Yun, Wang, Koh, Mariko Siyue, Ong, Thun How, Lim, Albert Yick Hou, Abisheganaden, John A., Low, Teck Boon, Hassan, Tidi Maharani, Long, Xiang, Wark, Peter A.B., Oliver, Brian, Drautz-Moses, Daniela I., Schuster, Stephan C., Tan, Nguan Soon, Fang, Mingliang, Chalmers, James D., Chotirmall, Sanjay H.
Published in Cell host & microbe (14.09.2022)
Published in Cell host & microbe (14.09.2022)
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Journal Article
Differential effects of microRNAs miR‐21, miR‐99 and miR‐145 on lung regeneration and inflammation during recovery from influenza pneumonia
Ong, Joe Wee Jian, Tan, Kai Sen, Lee, Joseph Jing Xian, Seet, Ju Ee, Choi, Hyung Won, Ler, Siok Ghee, Gunaratne, Jayantha, Narasaraju, Teluguakula, Sham, Lok‐To, Patzel, Volker, Chow, Vincent T.
Published in Journal of medical virology (01.12.2023)
Published in Journal of medical virology (01.12.2023)
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Journal Article
Transcriptomics of rhinovirus persistence reveals sustained expression of RIG‐I and interferon‐stimulated genes in nasal epithelial cells in vitro
Ong, Hsiao Hui, Andiappan, Anand Kumar, Duan, Kaibo, Lum, Josephine, Liu, Jing, Tan, Kai Sen, Howland, Shanshan, Lee, Bernett, Ong, Yew Kwang, Thong, Mark, Chow, Vincent T., Wang, De‐Yun
Published in Allergy (Copenhagen) (01.09.2022)
Published in Allergy (Copenhagen) (01.09.2022)
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Journal Article
Influence of glycan structure on the colonization of Streptococcus pneumoniae on human respiratory epithelial cells
Chun, Ye-Yu, Tan, Kai Sen, Yu, Lisa, Pang, Michelle, Wong, Ming Hui Millie, Nakamoto, Rei, Chua, Wan-Zhen, Huee-Ping Wong, Amanda, Lew, Zhe Zhang Ryan, Ong, Hsiao Hui, Chow, Vincent T, Tran, Thai, Yun Wang, De, Sham, Lok-To
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2023)
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Journal Article
Uncovering Novel Viral Innate Immune Evasion Strategies: What Has SARS-CoV-2 Taught Us?
Tay, Douglas Jie Wen, Lew, Zhe Zhang Ryan, Chu, Justin Jang Hann, Tan, Kai Sen
Published in Frontiers in microbiology (23.03.2022)
Published in Frontiers in microbiology (23.03.2022)
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