Development of bicarbonate buffer flow-through cell dissolution test and its application in prediction of in vivo performance of colon targeting tablets
Ikuta, Shotaro, Nakagawa, Hidetoshi, Kai, Toshiya, Sugano, Kiyohiko
Published in European journal of pharmaceutical sciences (01.01.2023)
Published in European journal of pharmaceutical sciences (01.01.2023)
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Preparation of Novel Functional Drug Particles Embedded in a Gelling–Swelling Layer (PEGS) for Taste Masking and Subsequent Rapid Drug Release
Ijitsu, Shin, Hoashi, Yohei, Hori, Koji, Okimoto, Kazuto, Kai, Toshiya, Yoshida, Miyako, Uchida, Takahiro
Published in Chemical & pharmaceutical bulletin (01.04.2021)
Published in Chemical & pharmaceutical bulletin (01.04.2021)
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Preparation of Solifenacin Succinate Functional Particles Embedded in a Gelling–Swelling Layer (PEGS) and Their Formulation in Orally Disintegrating Tablets
Ijitsu, Shin, Hoashi, Yohei, Hori, Koji, Okimoto, Kazuto, Kai, Toshiya, Yoshida, Miyako, Uchida, Takahiro
Published in Chemical & pharmaceutical bulletin (01.05.2021)
Published in Chemical & pharmaceutical bulletin (01.05.2021)
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Journal Article
Amino acids of importance for the antioxidant activity of human serum albumin as revealed by recombinant mutants and genetic variants
Anraku, Makoto, Shintomo, Rina, Taguchi, Kazuaki, Kragh-Hansen, Ulrich, Kai, Toshiya, Maruyama, Toru, Otagiri, Masaki
Published in Life sciences (1973) (01.08.2015)
Published in Life sciences (1973) (01.08.2015)
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S-Nitrosylated Human Serum Albumin-mediated Cytoprotective Activity Is Enhanced by Fatty Acid Binding
Ishima, Yu, Akaike, Takaaki, Kragh-Hansen, Ulrich, Hiroyama, Shuichi, Sawa, Tomohiro, Suenaga, Ayaka, Maruyama, Toru, Kai, Toshiya, Otagiri, Masaki
Published in The Journal of biological chemistry (12.12.2008)
Published in The Journal of biological chemistry (12.12.2008)
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Journal Article
Pharmacokinetic Study of Enclosed Hemoglobin and Outer Lipid Component after the Administration of Hemoglobin Vesicles as an Artificial Oxygen Carrier
TAGUCHI, Kazuaki, URATA, Yukino, OTAGIRI, Masaki, ANRAKU, Makoto, MARUYAMA, Toru, WATANABE, Hiroshi, SAKAI, Hiromi, HORINOUCHI, Hirohisa, KOBAYASHI, Koichi, TSUCHIDA, Eishun, KAI, Toshiya
Published in Drug metabolism and disposition (01.07.2009)
Published in Drug metabolism and disposition (01.07.2009)
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Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model
Taguchi, Kazuaki, Maruyama, Toru, Iwao, Yasunori, Sakai, Hiromi, Kobayashi, Koichi, Horinouchi, Hirohisa, Tsuchida, Eishun, Kai, Toshiya, Otagiri, Masaki
Published in Journal of controlled release (19.06.2009)
Published in Journal of controlled release (19.06.2009)
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Journal Article
The Structural and Pharmacokinetic Properties of Oxidized Human Serum Albumin, Advanced Oxidation Protein Products (AOPP)
Iwao, Yasunori, Anraku, Makoto, Hiraike, Mikako, Kawai, Keiichi, Nakajou, Keisuke, Kai, Toshiya, Suenaga, Ayaka, Otagiri, Masaki
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2006)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2006)
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Design and Evaluation of S-Nitrosylated Human Serum Albumin as a Novel Anticancer Drug
Katayama, Naohisa, Nakajou, Keisuke, Komori, Hisakazu, Uchida, Kunitoshi, Yokoe, Jun-Ichi, Yasui, Norikiyo, Yamamoto, Hisashi, Kai, Toshiya, Sato, Makoto, Nakagawa, Takenobu, Takeya, Motohiro, Maruyama, Toru, Otagiri, Masaki
Published in The Journal of pharmacology and experimental therapeutics (01.04.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2008)
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Journal Article
Preparation of Solifenacin Succinate Functional Particles Embedded in a Gelling-Swelling Layer (PEGS) and Their Formulation in Orally Disintegrating Tablets
Shin Ijitsua, Yohei Hoashia, Koji Horia, Kazuto Okimotoa, Toshiya Kaia, Miyako Yoshidab, Takahiro Uchidab
Published in Chemical and Pharmaceutical Bulletin (01.05.2021)
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Published in Chemical and Pharmaceutical Bulletin (01.05.2021)
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Chromium(III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation
Sato, Takashi, Ando, Yukio, Susuki, Seiko, Mikami, Fumi, Ikemizu, Shinji, Nakamura, Masaaki, Suhr, Ole, Anraku, Makoto, Kai, Toshiya, Suico, Mary Ann, Shuto, Tsuyoshi, Mizuguchi, Mineyuki, Yamagata, Yuriko, Kai, Hirofumi
Published in FEBS letters (23.01.2006)
Published in FEBS letters (23.01.2006)
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Bicarbonate buffer dissolution test with gentle mechanistic stress for bioequivalence prediction of enteric-coated pellet formulations
Ikuta, Shotaro, Nakagawa, Hidetoshi, Kai, Toshiya, Sugano, Kiyohiko
Published in European journal of pharmaceutical sciences (01.01.2024)
Published in European journal of pharmaceutical sciences (01.01.2024)
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Journal Article
CD36 Is Not Involved in Scavenger Receptor-Mediated Endocytic Uptake of Glycolaldehyde- and Methylglyoxal-Modified Proteins by Liver Endothelial Cells
Nakajou, Keisuke, Horiuchi, Seikoh, Sakai, Masakazu, Hirata, Kenshiro, Tanaka, Makiko, Takeya, Motohiro, Kai, Toshiya, Otagiri, Masaki
Published in Journal of biochemistry (Tokyo) (01.05.2005)
Published in Journal of biochemistry (Tokyo) (01.05.2005)
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Journal Article
Preparation of novel functional drug particles embedded in a gelling–swelling layer (PEGS) for taste masking and subsequent rapid drug release
Ijitsu, Shin, Hoashi, Yohei, Hori, Koji, Okimoto, Kazuto, Kai, Toshiya, Yoshida, Miyako, Uchida, Takahiro
Published in Chemical and Pharmaceutical Bulletin (2021)
Published in Chemical and Pharmaceutical Bulletin (2021)
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Journal Article
Preparation of solifenacin succinate functional particles embedded in a gelling–swelling layer (PEGS) and their formulation in orally disintegrating tablets
Ijitsu, Shin, Hoashi, Yohei, Hori, Koji, Okimoto, Kazuto, Kai, Toshiya, Yoshida, Miyako, Uchida, Takahiro
Published in Chemical and Pharmaceutical Bulletin (2021)
Published in Chemical and Pharmaceutical Bulletin (2021)
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Journal Article
S-Nitrosated Human Serum Albumin Dimer is not only a Novel Anti-Tumor Drug but also a Potentiator for Anti-Tumor Drugs with Augmented EPR Effects
Ishima, Yu, Chen, Di, Fang, Jun, Maeda, Hiroshi, Minomo, Ai, Kragh-Hansen, Ulrich, Kai, Toshiya, Maruyama, Toru, Otagiri, Masaki
Published in Bioconjugate chemistry (15.02.2012)
Published in Bioconjugate chemistry (15.02.2012)
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Polysaccharides as potential antioxidative compounds for extended-release matrix tablets
Tomida, Hisao, Yasufuku, Taira, Fujii, Takeshi, Kondo, Yuko, Kai, Toshiya, Anraku, Makoto
Published in Carbohydrate research (11.01.2010)
Published in Carbohydrate research (11.01.2010)
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Elucidation of the therapeutic enhancer mechanism of poly-S-nitrosated human serum albumin against multidrug-resistant tumor in animal models
Ishima, Yu, Hara, Marie, Kragh-Hansen, Ulrich, Inoue, Aki, Suenaga, Ayaka, Kai, Toshiya, Watanabe, Hiroshi, Otagiri, Masaki, Maruyama, Toru
Published in Journal of controlled release (28.11.2012)
Published in Journal of controlled release (28.11.2012)
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1P169 Over-expression of Recombinant Human Hemoglobin(5. Heme protein,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)
Uno, Tadayuki, Takefumi, Ishimaru, Takigawa, Sohtaro, Hoashi, Yohei, Kai, Toshiya, Tomisugi, Yoshikazu, Ishikawa, Yoshinobu, Maeda, Hatsuo
Published in Seibutsu Butsuri (2006)
Published in Seibutsu Butsuri (2006)
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