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Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2018)
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Cerebral Cavernous Malformation: From Mechanism to Therapy
Snellings, Daniel A, Hong, Courtney C, Ren, Aileen A, Lopez-Ramirez, Miguel A, Girard, Romuald, Srinath, Abhinav, Marchuk, Douglas A, Ginsberg, Mark H, Awad, Issam A, Kahn, Mark L
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Published in Circulation research (25.06.2021)
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Lymphatic impairment leads to pulmonary tertiary lymphoid organ formation and alveolar damage
Reed, Hasina Outtz, Wang, Liqing, Sonett, Jarrod, Chen, Mei, Yang, Jisheng, Li, Larry, Aradi, Petra, Jakus, Zoltan, D'Armiento, Jeanine, Hancock, Wayne W, Kahn, Mark L
Published in The Journal of clinical investigation (01.06.2019)
Published in The Journal of clinical investigation (01.06.2019)
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The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression
Zhou, Zinan, Rawnsley, David R., Goddard, Lauren M., Pan, Wei, Cao, Xing-Jun, Jakus, Zoltan, Zheng, Hui, Yang, Jisheng, Arthur, J. Simon C., Whitehead, Kevin J., Li, Dean, Zhou, Bin, Garcia, Benjamin A., Zheng, Xiangjian, Kahn, Mark L.
Published in Developmental cell (26.01.2015)
Published in Developmental cell (26.01.2015)
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PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism
Ren, Aileen A., Snellings, Daniel A., Su, Yourong S., Hong, Courtney C., Castro, Marco, Tang, Alan T., Detter, Matthew R., Hobson, Nicholas, Girard, Romuald, Romanos, Sharbel, Lightle, Rhonda, Moore, Thomas, Shenkar, Robert, Benavides, Christian, Beaman, M. Makenzie, Müller-Fielitz, Helge, Chen, Mei, Mericko, Patricia, Yang, Jisheng, Sung, Derek C., Lawton, Michael T., Ruppert, J. Michael, Schwaninger, Markus, Körbelin, Jakob, Potente, Michael, Awad, Issam A., Marchuk, Douglas A., Kahn, Mark L.
Published in Nature (London) (10.06.2021)
Published in Nature (London) (10.06.2021)
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Endothelial TLR4 and the microbiome drive cerebral cavernous malformations
Tang, Alan T., Choi, Jaesung P., Kotzin, Jonathan J., Yang, Yiqing, Hong, Courtney C., Hobson, Nicholas, Girard, Romuald, Zeineddine, Hussein A., Lightle, Rhonda, Moore, Thomas, Cao, Ying, Shenkar, Robert, Chen, Mei, Mericko, Patricia, Yang, Jisheng, Li, Li, Tanes, Ceylan, Kobuley, Dmytro, Võsa, Urmo, Whitehead, Kevin J., Li, Dean Y., Franke, Lude, Hart, Blaine, Schwaninger, Markus, Henao-Mejia, Jorge, Morrison, Leslie, Kim, Helen, Awad, Issam A., Zheng, Xiangjian, Kahn, Mark L.
Published in Nature (London) (18.05.2017)
Published in Nature (London) (18.05.2017)
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Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow
Betterman, Kelly L, Sutton, Drew L, Secker, Genevieve A, Kazenwadel, Jan, Oszmiana, Anna, Lim, Lillian, Miura, Naoyuki, Sorokin, Lydia, Hogan, Benjamin M, Kahn, Mark L, McNeill, Helen, Harvey, Natasha L
Published in The Journal of clinical investigation (01.06.2020)
Published in The Journal of clinical investigation (01.06.2020)
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Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD
Bui, Hung M, Enis, David, Robciuc, Marius R, Nurmi, Harri J, Cohen, Jennifer, Chen, Mei, Yang, Yiqing, Dhillon, Veerpal, Johnson, Kathy, Zhang, Hong, Kirkpatrick, Robert, Traxler, Elizabeth, Anisimov, Andrey, Alitalo, Kari, Kahn, Mark L
Published in The Journal of clinical investigation (01.06.2016)
Published in The Journal of clinical investigation (01.06.2016)
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Platelet ITAM signaling is critical for vascular integrity in inflammation
Boulaftali, Yacine, Hess, Paul R, Getz, Todd M, Cholka, Agnieszka, Stolla, Moritz, Mackman, Nigel, Owens, 3rd, A Phillip, Ware, Jerry, Kahn, Mark L, Bergmeier, Wolfgang
Published in The Journal of clinical investigation (01.02.2013)
Published in The Journal of clinical investigation (01.02.2013)
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Hemostasis stimulates lymphangiogenesis through release and activation of VEGFC
Lim, Lillian, Bui, Hung, Farrelly, Olivia, Yang, Jisheng, Li, Li, Enis, David, Ma, Wanshu, Chen, Mei, Oliver, Guillermo, Welsh, John D., Kahn, Mark L.
Published in Blood (14.11.2019)
Published in Blood (14.11.2019)
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Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis
Goddard, Lauren M., Duchemin, Anne-Laure, Ramalingan, Harini, Wu, Bingruo, Chen, Mei, Bamezai, Sharika, Yang, Jisheng, Li, Li, Morley, Michael P., Wang, Tao, Scherrer-Crosbie, Marielle, Frank, David B., Engleka, Kurt A., Jameson, Stephen C., Morrisey, Edward E., Carroll, Thomas J., Zhou, Bin, Vermot, Julien, Kahn, Mark L.
Published in Developmental cell (06.11.2017)
Published in Developmental cell (06.11.2017)
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Lymphatic mimicry in maternal endothelial cells promotes placental spiral artery remodeling
Pawlak, John B, Bálint, László, Lim, Lillian, Ma, Wanshu, Davis, Reema B, Benyó, Zoltán, Soares, Michael J, Oliver, Guillermo, Kahn, Mark L, Jakus, Zoltán, Caron, Kathleen M
Published in The Journal of clinical investigation (01.11.2019)
Published in The Journal of clinical investigation (01.11.2019)
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Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection
Tang, Alan T, Buchholz, David W, Szigety, Katherine M, Imbiakha, Brian, Gao, Siqi, Frankfurter, Maxwell, Wang, Min, Yang, Jisheng, Hewins, Peter, Mericko-Ishizuka, Patricia, Leu, N Adrian, Sterling, Stephanie, Monreal, Isaac A, Sahler, Julie, August, Avery, Zhu, Xuming, Jurado, Kellie A, Xu, Mingang, Morrisey, Edward E, Millar, Sarah E, Aguilar, Hector C, Kahn, Mark L
Published in PLoS biology (06.02.2023)
Published in PLoS biology (06.02.2023)
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Platelets regulate lymphatic vascular development through CLEC-2–SLP-76 signaling
Bertozzi, Cara C., Schmaier, Alec A., Mericko, Patricia, Hess, Paul R., Zou, Zhiying, Chen, Mei, Chen, Chiu-Yu, Xu, Bin, Lu, Min-min, Zhou, Diane, Sebzda, Eric, Santore, Matthew T., Merianos, Demetri J., Stadtfeld, Matthias, Flake, Alan W., Graf, Thomas, Skoda, Radek, Maltzman, Jonathan S., Koretzky, Gary A., Kahn, Mark L.
Published in Blood (29.07.2010)
Published in Blood (29.07.2010)
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VEGFR3 is required for button junction formation in lymphatic vessels
Jannaway, Melanie, Iyer, Drishya, Mastrogiacomo, Diandra M., Li, Kunyu, Sung, Derek C., Yang, Ying, Kahn, Mark L., Scallan, Joshua P.
Published in Cell reports (Cambridge) (25.07.2023)
Published in Cell reports (Cambridge) (25.07.2023)
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Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2
Acton, Sophie E., Astarita, Jillian L., Malhotra, Deepali, Lukacs-Kornek, Veronika, Franz, Bettina, Hess, Paul R., Jakus, Zoltan, Kuligowski, Michael, Fletcher, Anne L., Elpek, Kutlu G., Bellemare-Pelletier, Angelique, Sceats, Lindsay, Reynoso, Erika D., Gonzalez, Santiago F., Graham, Daniel B., Chang, Jonathan, Peters, Anneli, Woodruff, Matthew, Kim, Young-A., Swat, Wojciech, Morita, Takashi, Kuchroo, Vijay, Carroll, Michael C., Kahn, Mark L., Wucherpfennig, Kai W., Turley, Shannon J.
Published in Immunity (Cambridge, Mass.) (24.08.2012)
Published in Immunity (Cambridge, Mass.) (24.08.2012)
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