Antimicrobial Properties of Amyloid Peptides
Kagan, Bruce L, Jang, Hyunbum, Capone, Ricardo, Teran Arce, Fernando, Ramachandran, Srinivasan, Lal, Ratnesh, Nussinov, Ruth
Published in Molecular pharmaceutics (02.04.2012)
Published in Molecular pharmaceutics (02.04.2012)
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Journal Article
Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs
Jang, Hyunbum, Teran Arce, Fernando, Ramachandran, Srinivasan, Kagan, Bruce L, Lal, Ratnesh, Nussinov, Ruth
Published in Chemical Society reviews (07.10.2014)
Published in Chemical Society reviews (07.10.2014)
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Journal Article
Truncated β-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome
Jang, Hyunbum, Arce, Fernando Teran, Ramachandran, Srinivasan, Capone, Ricardo, Azimova, Rushana, Kagan, Bruce L, Nussinov, Ruth, Lal, Ratnesh
Published in Proceedings of the National Academy of Sciences - PNAS (06.04.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (06.04.2010)
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Journal Article
Ion Channel Formation by Tau Protein: Implications for Alzheimer’s Disease and Tauopathies
Patel, Nirav, Ramachandran, Srinivasan, Azimov, Rustam, Kagan, Bruce L, Lal, Ratnesh
Published in Biochemistry (Easton) (22.12.2015)
Published in Biochemistry (Easton) (22.12.2015)
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Journal Article
Mechanisms for the Insertion of Toxic, Fibril-like β‑Amyloid Oligomers into the Membrane
Jang, Hyunbum, Connelly, Laura, Teran Arce, Fernando, Ramachandran, Srinivasan, Kagan, Bruce L, Lal, Ratnesh, Nussinov, Ruth
Published in Journal of chemical theory and computation (08.01.2013)
Published in Journal of chemical theory and computation (08.01.2013)
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Journal Article
Membrane Pores in the Pathogenesis of Neurodegenerative Disease
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Book Chapter
Journal Article
Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-d-Enantiomer of Alzheimer’s β-Amyloid Peptide: Relevance to the Ion Channel Mechanism of AD Pathology
Connelly, Laura, Jang, Hyunbum, Teran Arce, Fernando, Capone, Ricardo, Kotler, Samuel A, Ramachandran, Srinivasan, Kagan, Bruce L, Nussinov, Ruth, Lal, Ratnesh
Published in The journal of physical chemistry. B (09.02.2012)
Published in The journal of physical chemistry. B (09.02.2012)
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Journal Article
Ion channel formation by N-terminally truncated Aβ (4–42): relevance for the pathogenesis of Alzheimer's disease
Karkisaval, Abhijith G, Rostagno, Agueda, Azimov, Rustam, Ban, Deependra K, Ghiso, Jorge, Kagan, Bruce L., Lal, Ratnesh
Published in Nanomedicine (01.10.2020)
Published in Nanomedicine (01.10.2020)
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Journal Article
Amyloid Ion Channels: A Common Structural Link for Protein-Misfolding Disease
Quist, Arjan, Doudevski, Ivo, Lin, Hai, Azimova, Rushana, Ng, Douglas, Frangione, Blas, Kagan, Bruce, Ghiso, Jorge, Lal, Ratnesh, Petsko, Gregory A.
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2005)
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Journal Article
Alzheimer's disease: which type of amyloid-preventing drug agents to employ?
Jang, Hyunbum, Connelly, Laura, Arce, Fernando Teran, Ramachandran, Srinivasan, Lal, Ratnesh, Kagan, Bruce L, Nussinov, Ruth
Published in Physical chemistry chemical physics : PCCP (21.06.2013)
Published in Physical chemistry chemical physics : PCCP (21.06.2013)
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Journal Article
Amyloid β Ion Channels in a Membrane Comprising Brain Total Lipid Extracts
Lee, Joon, Kim, Young Hun, T. Arce, Fernando, Gillman, Alan L, Jang, Hyunbum, Kagan, Bruce L, Nussinov, Ruth, Yang, Jerry, Lal, Ratnesh
Published in ACS chemical neuroscience (21.06.2017)
Published in ACS chemical neuroscience (21.06.2017)
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Journal Article
Role of the Fast Kinetics of Pyroglutamate-Modified Amyloid‑β Oligomers in Membrane Binding and Membrane Permeability
Lee, Joon, Gillman, Alan L, Jang, Hyunbum, Ramachandran, Srinivasan, Kagan, Bruce L, Nussinov, Ruth, Teran Arce, Fernando
Published in Biochemistry (Easton) (22.07.2014)
Published in Biochemistry (Easton) (22.07.2014)
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Journal Article
Effects of Point Substitutions on the Structure of Toxic Alzheimer’s β-Amyloid Channels: Atomic Force Microscopy and Molecular Dynamics Simulations
Connelly, Laura, Jang, Hyunbum, Teran Arce, Fernando, Ramachandran, Srinivasan, Kagan, Bruce L, Nussinov, Ruth, Lal, Ratnesh
Published in Biochemistry (Easton) (10.04.2012)
Published in Biochemistry (Easton) (10.04.2012)
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Journal Article
Familial Alzheimer’s Disease Osaka Mutant (ΔE22) β‑Barrels Suggest an Explanation for the Different Aβ1–40/42 Preferred Conformational States Observed by Experiment
Jang, Hyunbum, Teran Arce, Fernando, Ramachandran, Srinivasan, Kagan, Bruce L, Lal, Ratnesh, Nussinov, Ruth
Published in The journal of physical chemistry. B (03.10.2013)
Published in The journal of physical chemistry. B (03.10.2013)
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Journal Article
Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels
Jang, Hyunbum, Arce, Fernando Teran, Lee, Joon, Gillman, Alan L, Ramachandran, Srinivasan, Kagan, Bruce L, Lal, Ratnesh, Nussinov, Ruth
Published in Methods in molecular biology (Clifton, N.J.) (2016)
Published in Methods in molecular biology (Clifton, N.J.) (2016)
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Journal Article
Amyloid peptide pores and the beta sheet conformation
Kagan, Bruce L, Thundimadathil, Jyothi
Published in Advances in experimental medicine and biology (2010)
Published in Advances in experimental medicine and biology (2010)
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Journal Article