Nucleoside Phosphate and Phosphonate Prodrug Clinical Candidates
Thornton, Peter J, Kadri, Hachemi, Miccoli, Ageo, Mehellou, Youcef
Published in Journal of medicinal chemistry (08.12.2016)
Published in Journal of medicinal chemistry (08.12.2016)
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Journal Article
Kinetin Riboside and Its ProTides Activate the Parkinson’s Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization
Osgerby, Laura, Lai, Yu-Chiang, Thornton, Peter J, Amalfitano, Joseph, Le Duff, Cécile S, Jabeen, Iqra, Kadri, Hachemi, Miccoli, Ageo, Tucker, James H. R, Muqit, Miratul M. K, Mehellou, Youcef
Published in Journal of medicinal chemistry (27.04.2017)
Published in Journal of medicinal chemistry (27.04.2017)
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Journal Article
The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1
Barini, Erica, Miccoli, Ageo, Tinarelli, Federico, Mulholland, Katie, Kadri, Hachemi, Khanim, Farhat, Stojanovski, Laste, Read, Kevin D., Burness, Kerry, Blow, Julian J., Mehellou, Youcef, Muqit, Miratul M. K.
Published in Chembiochem : a European journal of chemical biology (02.03.2018)
Published in Chembiochem : a European journal of chemical biology (02.03.2018)
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Journal Article
Aryloxy Triester Phosphoramidates as Phosphoserine Prodrugs: A Proof of Concept Study
Miccoli, Ageo, Dhiani, Binar A., Thornton, Peter J., Lambourne, Olivia A., James, Edward, Kadri, Hachemi, Mehellou, Youcef
Published in ChemMedChem (20.04.2020)
Published in ChemMedChem (20.04.2020)
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Journal Article
The development of pro-apoptotic cancer therapeutics
Ziedan, Noha I, Kadri, Hachemi, Westwell, Andrew D
Published in Mini reviews in medicinal chemistry (01.06.2008)
Published in Mini reviews in medicinal chemistry (01.06.2008)
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Journal Article
A model for the behaviors and incentives of users in a decentralized data-sharing network
Esfandiari, Babak, Farid Amin, Ali Reza, Kadri, El Hachemi, Telfer, Andre
Published in Web Intelligence (01.01.2017)
Published in Web Intelligence (01.01.2017)
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Journal Article
Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of V gamma 9/V delta 2 T-Cell Immune Responses
Kadri, Hachemi, Taher, Taher E., Xu, Qin, Sharif, Maria, Ashby, Elizabeth, Bryan, Richard T., Willcox, Benjamin E., Mehellou, Youcef
Published in Journal of medicinal chemistry (08.10.2020)
Published in Journal of medicinal chemistry (08.10.2020)
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Journal Article
C-terminal phosphorylation of SPAK and OSR1 kinases promotes their binding and activation by the scaffolding protein MO25
Mehellou, Youcef, Alamri, Mubarak A., Dhiani, Binar A., Kadri, Hachemi
Published in Biochemical and biophysical research communications (10.09.2018)
Published in Biochemical and biophysical research communications (10.09.2018)
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Journal Article
Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T‑Cell Immune Responses
Kadri, Hachemi, Taher, Taher E, Xu, Qin, Sharif, Maria, Ashby, Elizabeth, Bryan, Richard T, Willcox, Benjamin E, Mehellou, Youcef
Published in Journal of medicinal chemistry (08.10.2020)
Published in Journal of medicinal chemistry (08.10.2020)
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Journal Article
Synthesis and antioxidant properties of substituted 2-phenyl-1H-indoles
Karaaslan, Cigdem, Kadri, Hachemi, Coban, Tulay, Suzen, Sibel, Westwell, Andrew D.
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Journal Article
Synthesis and Biological Properties of Benzothiazole, Benzoxazole, and Chromen-4-one Analogues of the Potent Antitumor Agent 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648)
Aiello, Stefania, Wells, Geoffrey, Stone, Erica L, Kadri, Hachemi, Bazzi, Rana, Bell, David R, Stevens, Malcolm F. G, Matthews, Charles S, Bradshaw, Tracey D, Westwell, Andrew D
Published in Journal of medicinal chemistry (28.08.2008)
Published in Journal of medicinal chemistry (28.08.2008)
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Journal Article
BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain
Salim, Mahboob, Knowles, Timothy J, Baker, Alfie T, Davey, Martin S, Jeeves, Mark, Sridhar, Pooja, Wilkie, John, Willcox, Carrie R, Kadri, Hachemi, Taher, Taher E, Vantourout, Pierre, Hayday, Adrian, Mehellou, Youcef, Mohammed, Fiyaz, Willcox, Benjamin E
Published in ACS chemical biology (20.10.2017)
Published in ACS chemical biology (20.10.2017)
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Journal Article
Nucleoside Phosphate and Phosphonate Prodrug Clinical Candidates: Miniperspective
Thornton, Peter J, Kadri, Hachemi, Miccoli, Ageo, Mehellou, Youcef
Published in Journal of medicinal chemistry (08.12.2016)
Published in Journal of medicinal chemistry (08.12.2016)
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Journal Article
WNK Signaling Inhibitors as Potential Antihypertensive Drugs
AlAmri, Mubarak A., Kadri, Hachemi, Dhiani, Binar A., Mahmood, Shumail, Elzwawi, Abdulrahman, Mehellou, Youcef
Published in ChemMedChem (20.10.2017)
Published in ChemMedChem (20.10.2017)
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Journal Article
Towards the Development of Small‐Molecule MO25 Binders as Potential Indirect SPAK/OSR1 Kinase Inhibitors
Kadri, Hachemi, Alamri, Mubarak A., Navratilova, Iva H., Alderwick, Luke J., Simpkins, Nigel S., Mehellou, Youcef
Published in Chembiochem : a European journal of chemical biology (02.03.2017)
Published in Chembiochem : a European journal of chemical biology (02.03.2017)
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Journal Article
Cover Picture: Towards the Development of Small‐Molecule MO25 Binders as Potential Indirect SPAK/OSR1 Kinase Inhibitors (ChemBioChem 5/2017)
Kadri, Hachemi, Alamri, Mubarak A., Navratilova, Iva H., Alderwick, Luke J., Simpkins, Nigel S., Mehellou, Youcef
Published in Chembiochem : a European journal of chemical biology (02.03.2017)
Published in Chembiochem : a European journal of chemical biology (02.03.2017)
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Journal Article