Block of Peripheral Nerve Sodium Channels Selectively Inhibits Features of Neuropathic Pain in Rats
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Published in Molecular pharmacology (01.03.2006)
Published in Molecular pharmacology (01.03.2006)
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Functional assay of voltage-gated sodium channels using membrane potential-sensitive dyes
Felix, John P, Williams, Brande S, Priest, Birgit T, Brochu, Richard M, Dick, Ivy E, Warren, Vivien A, Yan, Lizhen, Slaughter, Robert S, Kaczorowski, Gregory J, Smith, McHardy M, Garcia, Maria L
Published in Assay and drug development technologies (01.06.2004)
Published in Assay and drug development technologies (01.06.2004)
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Synthesis and SAR of 1,2- trans-(1-hydroxy-3-phenylprop-1-yl)cyclopentane carboxamide derivatives, a new class of sodium channel blockers
Ok, Dong, Li, Chunshi, Abbadie, Catherine, Felix, John P., Fisher, Michael H., Garcia, Maria L., Kaczorowski, Gregory J., Lyons, Kathryn A., Martin, William J., Priest, Birgit T., Smith, McHardy M., Williams, Brande S., Wyvratt, Matthew J., Parsons, William H.
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain
Liang, Jun, Brochu, Richard M., Cohen, Charles J., Dick, Ivy E., Felix, John P., Fisher, Michael H., Garcia, Maria L., Kaczorowski, Gregory J., Lyons, Kathryn A., Meinke, Peter T., Priest, Birgit T., Schmalhofer, William A., Smith, McHardy M., Tarpley, Jason W., Williams, Brande S., Martin, William J., Parsons, William H.
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
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Distribution of high-conductance Ca(2+)-activated K+ channels in rat brain: targeting to axons and nerve terminals
Knaus, HG, Schwarzer, C, Koch, RO, Eberhart, A, Kaczorowski, GJ, Glossmann, H, Wunder, F, Pongs, O, Garcia, ML, Sperk, G
Published in The Journal of neuroscience (01.02.1996)
Published in The Journal of neuroscience (01.02.1996)
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Sodium Channel Blockade May Contribute to the Analgesic Efficacy of Antidepressants
Dick, Ivy E, Brochu, Richard M, Purohit, Yamini, Kaczorowski, Gregory J, Martin, William J, Priest, Birgit T
Published in The journal of pain (01.04.2007)
Published in The journal of pain (01.04.2007)
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Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca(V)2 calcium channels
Swensen, Andrew M, Herrington, James, Bugianesi, Randal M, Dai, Ge, Haedo, Rodolfo J, Ratliff, Kevin S, Smith, McHardy M, Warren, Vivien A, Arneric, Stephen P, Eduljee, Cyrus, Parker, David, Snutch, Terrance P, Hoyt, Scott B, London, Clare, Duffy, Joseph L, Kaczorowski, Gregory J, McManus, Owen B
Published in Molecular pharmacology (01.03.2012)
Published in Molecular pharmacology (01.03.2012)
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Blockers of the Delayed-Rectifier Potassium Current in Pancreatic β-Cells Enhance Glucose-Dependent Insulin Secretion
Herrington, James, Zhou, Yun-Ping, Bugianesi, Randal M, Dulski, Paula M, Feng, Yue, Warren, Vivien A, Smith, McHardy M, Kohler, Martin G, Garsky, Victor M, Sanchez, Manuel, Wagner, Michael, Raphaelli, Kristin, Banerjee, Priya, Ahaghotu, Chinweze, Wunderler, Denise, Priest, Birgit T, Mehl, John T, Garcia, Maria L, McManus, Owen B, Kaczorowski, Gregory J, Slaughter, Robert S
Published in Diabetes (New York, N.Y.) (01.04.2006)
Published in Diabetes (New York, N.Y.) (01.04.2006)
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Blocking sodium channels to treat neuropathic pain
Priest, Birgit T, Kaczorowski, Gregory J
Published in Expert opinion on therapeutic targets (01.03.2007)
Published in Expert opinion on therapeutic targets (01.03.2007)
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Ion channels as drug targets: the next GPCRs
Kaczorowski, Gregory J, McManus, Owen B, Priest, Birgit T, Garcia, Maria L
Published in The Journal of general physiology (01.05.2008)
Published in The Journal of general physiology (01.05.2008)
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Expression of Voltage-Gated Potassium Channels in Human and Rhesus Pancreatic Islets
Yan, Lizhen, Figueroa, David J, Austin, Christopher P, Liu, Yuan, Bugianesi, Randal M, Slaughter, Robert S, Kaczorowski, Gregory J, Kohler, Martin G
Published in Diabetes (New York, N.Y.) (01.03.2004)
Published in Diabetes (New York, N.Y.) (01.03.2004)
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Pharmacology of voltage-gated and calcium-activated potassium channels
Kaczorowski, Gregory J, Garcia, Maria L
Published in Current opinion in chemical biology (01.08.1999)
Published in Current opinion in chemical biology (01.08.1999)
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A potent and selective indole N-type calcium channel (Ca(v)2.2) blocker for the treatment of pain
Tyagarajan, Sriram, Chakravarty, Prasun K, Park, Min, Zhou, Bishan, Herrington, James B, Ratliff, Kevin, Bugianesi, Randall M, Williams, Brande, Haedo, Rodolfo J, Swensen, Andrew M, Warren, Vivien A, Smith, McHardy, Garcia, Maria, Kaczorowski, Gregory J, McManus, Owen B, Lyons, Kathryn A, Li, Xiaohua, Madeira, Maria, Karanam, Bindhu, Green, Mitchell, Forrest, Michael J, Abbadie, Catherine, McGowan, Erin, Mistry, Shruti, Jochnowitz, Nina, Duffy, Joseph L
Published in Bioorganic & medicinal chemistry letters (15.01.2011)
Published in Bioorganic & medicinal chemistry letters (15.01.2011)
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Substituted biaryl pyrazoles as sodium channel blockers
Tyagarajan, Sriram, Chakravarty, Prasun K., Zhou, Bishan, Taylor, Brett, Fisher, Michael H., Wyvratt, Mathew J., Lyons, Kathy, Klatt, Tracy, Li, Xiaohua, Kumar, Sanjeev, Williams, Brande, Felix, John, Priest, Birgit T., Brochu, Richard M., Warren, Vivien, Smith, McHardy, Garcia, Maria, Kaczorowski, Gregory J., Martin, William J., Abbadie, Catherine, McGowan, Erin, Jochnowitz, Nina, Parsons, William H.
Published in Bioorganic & medicinal chemistry letters (15.09.2010)
Published in Bioorganic & medicinal chemistry letters (15.09.2010)
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Potassium channels: from scorpion venoms to high-resolution structure
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Book Review
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Discovery of a novel class of isoxazoline voltage gated sodium channel blockers
Shao, Pengcheng P., Ye, Feng, Weber, Ann E., Li, Xiaohua, Lyons, Kathryn A., Parsons, William H., Garcia, Maria L., Priest, Birgit T., Smith, McHardy M., Felix, John P., Williams, Brande S., Kaczorowski, Gregory J., McGowan, Erin, Abbadie, Catherine, Martin, William J., McMasters, Daniel R., Gao, Ying-Duo
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
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Discovery of isoxazole voltage gated sodium channel blockers for treatment of chronic pain
Shao, Pengcheng P., Ye, Feng, Weber, Ann E., Li, Xiaohua, Lyons, Kathryn A., Parsons, William H., Garcia, Maria L., Priest, Birgit T., Smith, McHardy M., Felix, John P., Williams, Brande S., Kaczorowski, Gregory J., McGowan, Erin, Abbadie, Catherine, Martin, William J., McMasters, Daniel R., Gao, Ying-Duo
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
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