De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy
Barcia, Giulia, Fleming, Matthew R, Deligniere, Aline, Gazula, Valeswara-Rao, Brown, Maile R, Langouet, Maeva, Chen, Haijun, Kronengold, Jack, Abhyankar, Avinash, Cilio, Roberta, Nitschke, Patrick, Kaminska, Anna, Boddaert, Nathalie, Casanova, Jean-Laurent, Desguerre, Isabelle, Munnich, Arnold, Dulac, Olivier, Kaczmarek, Leonard K, Colleaux, Laurence, Nabbout, Rima
Published in Nature genetics (01.11.2012)
Published in Nature genetics (01.11.2012)
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Journal Article
International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels
Kaczmarek, Leonard K, Aldrich, Richard W, Chandy, K George, Grissmer, Stephan, Wei, Aguan D, Wulff, Heike
Published in Pharmacological reviews (01.01.2017)
Published in Pharmacological reviews (01.01.2017)
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Journal Article
More than a pore: ion channel signaling complexes
Lee, Amy, Fakler, Bernd, Kaczmarek, Leonard K, Isom, Lori L
Published in The Journal of neuroscience (12.11.2014)
Published in The Journal of neuroscience (12.11.2014)
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Journal Article
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia
Onorati, Marco, Li, Zhen, Liu, Fuchen, Sousa, André M.M., Nakagawa, Naoki, Li, Mingfeng, Dell’Anno, Maria Teresa, Gulden, Forrest O., Pochareddy, Sirisha, Tebbenkamp, Andrew T.N., Han, Wenqi, Pletikos, Mihovil, Gao, Tianliuyun, Zhu, Ying, Bichsel, Candace, Varela, Luis, Szigeti-Buck, Klara, Lisgo, Steven, Zhang, Yalan, Testen, Anze, Gao, Xiao-Bing, Mlakar, Jernej, Popovic, Mara, Flamand, Marie, Strittmatter, Stephen M., Kaczmarek, Leonard K., Anton, E.S., Horvath, Tamas L., Lindenbach, Brett D., Sestan, Nenad
Published in Cell reports (Cambridge) (01.09.2016)
Published in Cell reports (Cambridge) (01.09.2016)
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An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack KNa Currents
Quraishi, Imran H, Stern, Shani, Mangan, Kile P, Zhang, Yalan, Ali, Syed R, Mercier, Michael R, Marchetto, Maria C, McLachlan, Michael J, Jones, Eugenia M, Gage, Fred H, Kaczmarek, Leonard K
Published in The Journal of neuroscience (11.09.2019)
Published in The Journal of neuroscience (11.09.2019)
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Journal Article
Human slack potassium channel mutations increase positive cooperativity between individual channels
Kim, Grace E, Kronengold, Jack, Barcia, Giulia, Quraishi, Imran H, Martin, Hilary C, Blair, Edward, Taylor, Jenny C, Dulac, Olivier, Colleaux, Laurence, Nabbout, Rima, Kaczmarek, Leonard K
Published in Cell reports (Cambridge) (11.12.2014)
Published in Cell reports (Cambridge) (11.12.2014)
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Journal Article
Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1
Zhang, Yalan, Varela, Luis, Szigeti-Buck, Klara, Williams, Adam, Stoiljkovic, Milan, Šestan-Peša, Matija, Henao-Mejia, Jorge, D’Acunzo, Pasquale, Levy, Efrat, Flavell, Richard A., Horvath, Tamas L., Kaczmarek, Leonard K.
Published in Nature communications (19.03.2021)
Published in Nature communications (19.03.2021)
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Journal Article
Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating
Zhang, Yalan, Zhang, Xiao-Feng, Fleming, Matthew R., Amiri, Anahita, El-Hassar, Lynda, Surguchev, Alexei A., Hyland, Callen, Jenkins, David P., Desai, Rooma, Brown, Maile R., Gazula, Valeswara-Rao, Waters, Michael F., Large, Charles H., Horvath, Tamas L., Navaratnam, Dhasakumar, Vaccarino, Flora M., Forscher, Paul, Kaczmarek, Leonard K.
Published in Cell (07.04.2016)
Published in Cell (07.04.2016)
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Journal Article
The voltage-gated K+ channel Kv1.3 modulates platelet motility and α2β1 integrin-dependent adhesion to collagen
Wright, Joy R, Jones, Sarah, Parvathy, Sasikumar, Kaczmarek, Leonard K, Forsythe, Ian, Farndale, Richard W, Gibbins, Jonathan M, Mahaut-Smith, Martyn P
Published in Platelets (Edinburgh) (03.04.2022)
Published in Platelets (Edinburgh) (03.04.2022)
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Journal Article
Stimulation of Slack K+ Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex
Fleming, Matthew R., Brown, Maile R., Kronengold, Jack, Zhang, Yalan, Jenkins, David P., Barcia, Gulia, Nabbout, Rima, Bausch, Anne E., Ruth, Peter, Lukowski, Robert, Navaratnam, Dhasakumar S., Kaczmarek, Leonard K.
Published in Cell reports (Cambridge) (30.08.2016)
Published in Cell reports (Cambridge) (30.08.2016)
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Journal Article
Modulation of potassium conductances optimizes fidelity of auditory information
Kaczmarek, Leonard K
Published in Proceedings of the National Academy of Sciences - PNAS (21.03.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (21.03.2023)
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