Systematic humanization of yeast genes reveals conserved functions and genetic modularity
Kachroo, Aashiq H., Laurent, Jon M., Yellman, Christopher M., Meyer, Austin G., Wilke, Claus O., Marcotte, Edward M.
Published in Science (American Association for the Advancement of Science) (22.05.2015)
Published in Science (American Association for the Advancement of Science) (22.05.2015)
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Journal Article
Systematic bacterialization of yeast genes identifies a near-universally swappable pathway
Kachroo, Aashiq H, Laurent, Jon M, Akhmetov, Azat, Szilagyi-Jones, Madelyn, McWhite, Claire D, Zhao, Alice, Marcotte, Edward M
Published in eLife (29.06.2017)
Published in eLife (29.06.2017)
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Journal Article
A Humanized Yeast Model for Studying TRAPP Complex Mutations; Proof-of-Concept Using Variants from an Individual with a TRAPPC1-Associated Neurodevelopmental Syndrome
Zykaj, Erta, Abboud, Chelsea, Asadi, Paria, Warsame, Simane, Almousa, Hashem, Milev, Miroslav P., Greco, Brittany M., López-Sánchez, Marcos, Bratkovic, Drago, Kachroo, Aashiq H., Pérez-Jurado, Luis Alberto, Sacher, Michael
Published in Cells (Basel, Switzerland) (30.08.2024)
Published in Cells (Basel, Switzerland) (30.08.2024)
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Journal Article
Yeast Cells Expressing the Human Mitochondrial DNA Polymerase Reveal Correlations between Polymerase Fidelity and Human Disease Progression
Qian, Yufeng, Kachroo, Aashiq H., Yellman, Christopher M., Marcotte, Edward M., Johnson, Kenneth A.
Published in The Journal of biological chemistry (28.02.2014)
Published in The Journal of biological chemistry (28.02.2014)
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Journal Article
An Overview of Tyrosine Site-specific Recombination: From an Flp Perspective
Jayaram, Makkuni, Ma, Chien-Hui, Kachroo, Aashiq H, Rowley, Paul A, Guga, Piotr, Fan, Hsui-Fang, Voziyanov, Yuri
Published in Microbiology spectrum (01.08.2015)
Published in Microbiology spectrum (01.08.2015)
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Journal Article
Functional Analysis of the Genes Encoding Diaminopropionate Ammonia Lyase in Escherichia coli and Salmonella enterica Serovar Typhimurium
KALYANI, J. N, RAMACHANDRA, Nagaraju, KACHROO, Aashiq H, MAHADEVAN, S, SAVITHRI, H. S
Published in Journal of Bacteriology (01.10.2012)
Published in Journal of Bacteriology (01.10.2012)
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Journal Article
Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase
Ma, Chien-Hui, Kachroo, Aashiq H, Macieszak, Anna, Chen, Tzu-Yang, Guga, Piotr, Jayaram, Makkuni
Published in PloS one (30.09.2009)
Published in PloS one (30.09.2009)
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Journal Article
The Many Nuanced Evolutionary Consequences of Duplicated Genes
Teufel, Ashley I, Johnson, Mackenzie M, Laurent, Jon M, Kachroo, Aashiq H, Marcotte, Edward M, Wilke, Claus O
Published in Molecular biology and evolution (01.02.2019)
Published in Molecular biology and evolution (01.02.2019)
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Journal Article
Efforts to make and apply humanized yeast
Laurent, Jon M, Young, Jonathan H, Kachroo, Aashiq H, Marcotte, Edward M
Published in Briefings in functional genomics (01.03.2016)
Published in Briefings in functional genomics (01.03.2016)
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Journal Article
Discovery of new vascular disrupting agents based on evolutionarily conserved drug action, pesticide resistance mutations, and humanized yeast
Garge, Riddhiman K, Cha, Hye Ji, Lee, Chanjae, Gollihar, Jimmy D, Kachroo, Aashiq H, Wallingford, John B, Marcotte, Edward M
Published in Genetics (Austin) (01.09.2021)
Published in Genetics (Austin) (01.09.2021)
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Journal Article
Hexapeptides That Inhibit Processing of Branched DNA Structures Induce a Dynamic Ensemble of Holliday Junction Conformations
Cannon, Brian, Kachroo, Aashiq H., Jarmoskaite, Inga, Jayaram, Makkuni, Russell, Rick
Published in The Journal of biological chemistry (11.09.2015)
Published in The Journal of biological chemistry (11.09.2015)
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Journal Article
Rapid, scalable, combinatorial genome engineering by marker-less enrichment and recombination of genetically engineered loci in yeast
Abdullah, Mudabir, Greco, Brittany M., Laurent, Jon M., Garge, Riddhiman K., Boutz, Daniel R., Vandeloo, Michelle, Marcotte, Edward M., Kachroo, Aashiq H.
Published in Cell reports methods (22.05.2023)
Published in Cell reports methods (22.05.2023)
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Journal Article
Stereospecific suppression of active site mutants by methylphosphonate substituted substrates reveals the stereochemical course of site-specific DNA recombination
Rowley, Paul A, Kachroo, Aashiq H, Ma, Chien-Hui, Maciaszek, Anna D, Guga, Piotr, Jayaram, Makkuni
Published in Nucleic acids research (13.07.2015)
Published in Nucleic acids research (13.07.2015)
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Journal Article
Electrostatic Suppression Allows Tyrosine Site-specific Recombination in the Absence of a Conserved Catalytic Arginine
Rowley, Paul A., Kachroo, Aashiq H., Ma, Chien-Hui, Maciaszek, Anna D., Guga, Piotr, Jayaram, Makkuni
Published in The Journal of biological chemistry (23.07.2010)
Published in The Journal of biological chemistry (23.07.2010)
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Journal Article
The partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells
Liu, Yen-Ting, Sau, Saumitra, Ma, Chien-Hui, Kachroo, Aashiq H, Rowley, Paul A, Chang, Keng-Ming, Fan, Hsiu-Fang, Jayaram, Makkuni
Published in Microbiology spectrum (01.10.2014)
Published in Microbiology spectrum (01.10.2014)
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