Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis
El-Naggar, Amal M., Veinotte, Chansey J., Cheng, Hongwei, Grunewald, Thomas G.P., Negri, Gian Luca, Somasekharan, Syam Prakash, Corkery, Dale P., Tirode, Franck, Mathers, Joan, Khan, Debjit, Kyle, Alastair H., Baker, Jennifer H., LePard, Nancy E., McKinney, Steven, Hajee, Shamil, Bosiljcic, Momir, Leprivier, Gabriel, Tognon, Cristina E., Minchinton, Andrew I., Bennewith, Kevin L., Delattre, Olivier, Wang, Yuzhuo, Dellaire, Graham, Berman, Jason N., Sorensen, Poul H.
Published in Cancer cell (11.05.2015)
Published in Cancer cell (11.05.2015)
Get full text
Journal Article
Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically
Chafe, Shawn C, McDonald, Paul C, Saberi, Saeed, Nemirovsky, Oksana, Venkateswaran, Geetha, Burugu, Samantha, Gao, Dongxia, Delaidelli, Alberto, Kyle, Alastair H, Baker, Jennifer H E, Gillespie, Jordan A, Bashashati, Ali, Minchinton, Andrew I, Zhou, Youwen, Shah, Sohrab P, Dedhar, Shoukat
Published in Cancer immunology research (01.07.2019)
Published in Cancer immunology research (01.07.2019)
Get more information
Journal Article
DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost
Wang, Taixiang, Kyle, Alastair H, Baker, Jennifer H E, Liu, Nannan A, Banáth, Judit P, Minchinton, Andrew I
Published in Scientific reports (01.08.2023)
Published in Scientific reports (01.08.2023)
Get full text
Journal Article
The Prognostic Impact of CD163-Positive Macrophages in Follicular Lymphoma: A Study from the BC Cancer Agency and the Lymphoma Study Association
Kridel, Robert, Xerri, Luc, Gelas-Dore, Bénédicte, Tan, King, Feugier, Pierre, Vawda, Ayesha, Canioni, Danielle, Farinha, Pedro, Boussetta, Sami, Moccia, Alden A, Brice, Pauline, Chavez, Elizabeth A, Kyle, Alastair H, Scott, David W, Sanders, Ashley D, Fabiani, Bettina, Slack, Graham W, Minchinton, Andrew I, Haioun, Corinne, Connors, Joseph M, Sehn, Laurie H, Steidl, Christian, Gascoyne, Randy D, Salles, Gilles
Published in Clinical cancer research (01.08.2015)
Published in Clinical cancer research (01.08.2015)
Get full text
Journal Article
Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling
Chang, Linda, Noseda, Michela, Higginson, Michelle, Ly, Michelle, Patenaude, Alexandre, Fuller, Megan, Kyle, Alastair H, Minchinton, Andrew I, Puri, Mira C, Dumont, Daniel J, Karsan, Aly
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2012)
Get full text
Journal Article
Limited Tissue Penetration of Taxanes: A Mechanism for Resistance in Solid Tumors
KYLE, Alastair H, HUXHAM, Lynsey A, YEOMAN, Devon M, MINCHINTON, Andrew I
Published in Clinical cancer research (01.05.2007)
Published in Clinical cancer research (01.05.2007)
Get full text
Journal Article
Direct Visualization of Heterogeneous Extravascular Distribution of Trastuzumab in Human Epidermal Growth Factor Receptor Type 2 Overexpressing Xenografts
BAKER, Jennifer H. E, LINDQUIST, Kirstin E, HUXHAM, Lynsey A, KYLE, Alastair H, SY, Jonathan T, MINCHINTON, Andrew I
Published in Clinical cancer research (01.04.2008)
Published in Clinical cancer research (01.04.2008)
Get full text
Journal Article
Targeting Quiescent Tumor Cells via Oxygen and IGF-I Supplementation
KYLE, Alastair H, BAKER, Jennifer H. E, MINCHINTON, Andrew I
Published in Cancer research (Chicago, Ill.) (01.02.2012)
Published in Cancer research (Chicago, Ill.) (01.02.2012)
Get full text
Journal Article
Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin
Baker, Jennifer H E, Kyle, Alastair H, Bartels, Kirsten L, Methot, Stephen P, Flanagan, Erin J, Balbirnie, Andrew, Cran, Jordan D, Minchinton, Andrew I
Published in PloS one (28.10.2013)
Published in PloS one (28.10.2013)
Get full text
Journal Article
Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK)
Edwards, Lincoln A, Woo, Janet, Huxham, Lynsey A, Verreault, Maite, Dragowska, Wieslawa H, Chiu, Gigi, Rajput, Ashish, Kyle, Alastair H, Kalra, Jessica, Yapp, Donald, Yan, Hong, Minchinton, Andrew I, Huntsman, David, Daynard, Tim, Waterhouse, Dawn N, Thiessen, B, Dedhar, Shoukat, Bally, Marcel B
Published in Molecular cancer therapeutics (01.01.2008)
Published in Molecular cancer therapeutics (01.01.2008)
Get full text
Journal Article
Angiopoietin-2 Functions as a Tie2 Agonist in Tumor Models, Where It Limits the Effects of VEGF Inhibition
DALY, Christopher, EICHTEN, Alexandra, THURSTON, Gavin, CASTANARO, Carla, PASNIKOWSKI, Elizabeth, ADLER, Alexander, LALANI, Alshad S, PAPADOPOULOS, Nicholas, KYLE, Alastair H, MINCHINTON, Andrew I, YANCOPOULOS, George D
Published in Cancer research (Chicago, Ill.) (2013)
Published in Cancer research (Chicago, Ill.) (2013)
Get full text
Journal Article
Silencing Bcl-2 in models of mantle cell lymphoma is associated with decreases in cyclin D1, nuclear factor-κB, p53, bax, and p27 levels
Tucker, Catherine A., Kapanen, Anita I., Chikh, Ghania, Hoffman, Brad G., Kyle, Alastair H., Wilson, Ian M., Masin, Dana, Gascoyne, Randy D., Bally, Marcel, Klasa, Richard J.
Published in Molecular cancer therapeutics (01.04.2008)
Published in Molecular cancer therapeutics (01.04.2008)
Get full text
Journal Article
Radiation and chemo-sensitizing effects of DNA-PK inhibitors are proportional in tumors and normal tissues
Baker, Jennifer H E, Kyle, Alastair H, Liu, Nannan Anam, Wang, Taixiang, Liu, Xinhe, Teymori, Sevin, Banáth, Judit P, Minchinton, Andrew I
Published in Molecular cancer therapeutics (04.09.2024)
Published in Molecular cancer therapeutics (04.09.2024)
Get full text
Journal Article
Detection of FLASH-radiotherapy tissue sparing in a 3D-spheroid model using DNA damage response markers
Kyle, Alastair H., Karan, Tania, Baker, Jennifer H.E., Püspöky Banáth, Judit, Wang, Taixiang, Liu, Anam, Mendez, Claudia, Peter Petric, M., Duzenli, Cheryl, Minchinton, Andrew I.
Published in Radiotherapy and oncology (01.07.2024)
Published in Radiotherapy and oncology (01.07.2024)
Get full text
Journal Article
DNA-PK inhibitor AZD7648 is a more portent radiosensitizer than PARP inhibitor Olaparib in BRCA1/2 deficient tumors
Wang, Taixiang, Kyle, Alastair H., Baker, Jennifer H.E., Liu, Nannan A., Banáth, Judit P., Teymori, Sevin, Minchinton, Andrew I.
Published in DNA repair (01.07.2024)
Published in DNA repair (01.07.2024)
Get full text
Journal Article
Detecting Vascular-Targeting Effects of the Hypoxic Cytotoxin Tirapazamine in Tumor Xenografts Using Magnetic Resonance Imaging
Bains, Lauren J., M.Sc, Baker, Jennifer H.E., B.Sc, Kyle, Alastair H., Ph.D, Minchinton, Andrew I., Ph.D, Reinsberg, Stefan A., Ph.D
Published in International journal of radiation oncology, biology, physics (01.07.2009)
Published in International journal of radiation oncology, biology, physics (01.07.2009)
Get full text
Journal Article
Characterization of Three-Dimensional Tissue Cultures Using Electrical Impedance Spectroscopy
Kyle, Alastair H., Chan, Carmel T.O., Minchinton, Andrew I.
Published in Biophysical journal (01.05.1999)
Published in Biophysical journal (01.05.1999)
Get full text
Journal Article
Endothelial-Specific Notch Blockade Inhibits Vascular Function and Tumor Growth through an eNOS-Dependent Mechanism
PATENAUDE, Alexandre, FULLER, Megan, TONG, Jade, MINCHINTON, Andrew I, KARSAN, Aly, CHANG, Linda, WONG, Fred, PALIOURAS, Grigorios, SHAW, Rebecca, KYLE, Alastair H, UMLANDT, Patricia, BAKER, Jennifer H. E, DIAZ, Erika
Published in Cancer research (Chicago, Ill.) (01.05.2014)
Published in Cancer research (Chicago, Ill.) (01.05.2014)
Get full text
Journal Article
The differential effects of metronomic gemcitabine and antiangiogenic treatment in patient-derived xenografts of pancreatic cancer: treatment effects on metabolism, vascular function, cell proliferation, and tumor growth
Yapp, Donald T., Wong, May Q., Kyle, Alastair H., Valdez, Shannon M., Tso, Jenny, Yung, Andrew, Kozlowski, Piotr, Owen, David A., Buczkowski, Andrzej K., Chung, Stephen W., Scudamore, Charles H., Minchinton, Andrew I., Ng, Sylvia S. W.
Published in Angiogenesis (London) (01.04.2016)
Published in Angiogenesis (London) (01.04.2016)
Get full text
Journal Article