MET Tyrosine Kinase Inhibitor Crizotinib (PF-02341066) Shows Differential Antitumor Effects in Non-small Cell Lung Cancer According to MET Alterations
Tanizaki, Junko, Okamoto, Isamu, Okamoto, Kunio, Takezawa, Ken, Kuwata, Kiyoko, Yamaguchi, Haruka, Nakagawa, Kazuhiko
Published in Journal of thoracic oncology (01.10.2011)
Published in Journal of thoracic oncology (01.10.2011)
Get full text
Journal Article
Activation of HER Family Signaling as a Mechanism of Acquired Resistance to ALK Inhibitors in EML4-ALK―Positive Non―Small Cell Lung Cancer
TANIZAKI, Junko, OKAMOTO, Isamu, HATASHITA, Erina, NISHIO, Kazuto, NAKAGAWA, Kazuhiko, OKABE, Takafumi, SAKAI, Kazuko, TANAKA, Kaoru, HAYASHI, Hidetoshi, KANEDA, Hiroyasu, TAKEZAWA, Ken, KUWATA, Kiyoko, YAMAGUCHI, Haruka
Published in Clinical cancer research (15.11.2012)
Published in Clinical cancer research (15.11.2012)
Get full text
Journal Article
Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification
Okamoto, Wataru, Okamoto, Isamu, Arao, Tokuzo, Kuwata, Kiyoko, Hatashita, Erina, Yamaguchi, Haruka, Sakai, Kazuko, Yanagihara, Kazuyoshi, Nishio, Kazuto, Nakagawa, Kazuhiko
Published in Molecular cancer therapeutics (01.07.2012)
Published in Molecular cancer therapeutics (01.07.2012)
Get full text
Journal Article
Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations
Okamoto, Kunio, Okamoto, Isamu, Okamoto, Wataru, Tanaka, Kaoru, Takezawa, Ken, Kuwata, Kiyoko, Yamaguchi, Haruka, Nishio, Kazuto, Nakagawa, Kazuhiko
Published in Cancer research (Chicago, Ill.) (15.12.2010)
Published in Cancer research (Chicago, Ill.) (15.12.2010)
Get full text
Journal Article
Overcoming erlotinib resistance in EGFR mutation-positive non-small cell lung cancer cells by targeting survivin
Okamoto, Kunio, Okamoto, Isamu, Hatashita, Erina, Kuwata, Kiyoko, Yamaguchi, Haruka, Kita, Aya, Yamanaka, Kentaro, Ono, Mayumi, Nakagawa, Kazuhiko
Published in Molecular cancer therapeutics (01.01.2012)
Published in Molecular cancer therapeutics (01.01.2012)
Get full text
Journal Article
MET amplification as a potential therapeutic target in gastric cancer
Kawakami, Hisato, Okamoto, Isamu, Arao, Tokuzo, Okamoto, Wataru, Matsumoto, Kazuko, Taniguchi, Hirokazu, Kuwata, Kiyoko, Yamaguchi, Haruka, Nishio, Kazuto, Nakagawa, Kazuhiko, Yamada, Yasuhide
Published in Oncotarget (01.01.2013)
Published in Oncotarget (01.01.2013)
Get full text
Journal Article
Effects of Src inhibitors on cell growth and epidermal growth factor receptor and MET signaling in gefitinib‐resistant non‐small cell lung cancer cells with acquired MET amplification
Yoshida, Takeshi, Okamoto, Isamu, Okamoto, Wataru, Hatashita, Erina, Yamada, Yuki, Kuwata, Kiyoko, Nishio, Kazuto, Fukuoka, Masahiro, Jänne, Pasi A., Nakagawa, Kazuhiko
Published in Cancer science (01.01.2010)
Published in Cancer science (01.01.2010)
Get full text
Journal Article
Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition
Okamoto, Wataru, Okamoto, Isamu, Yoshida, Takeshi, Okamoto, Kunio, Takezawa, Ken, Hatashita, Erina, Yamada, Yuki, Kuwata, Kiyoko, Arao, Tokuzo, Yanagihara, Kazuyoshi, Fukuoka, Masahiro, Nishio, Kazuto, Nakagawa, Kazuhiko
Published in Molecular cancer therapeutics (01.05.2010)
Published in Molecular cancer therapeutics (01.05.2010)
Get full text
Journal Article
Enhanced anticancer effect of the combination of BIBW2992 and thymidylate synthase-targeted agents in non-small cell lung cancer with the T790M mutation of epidermal growth factor receptor
Takezawa, Ken, Okamoto, Isamu, Tanizaki, Junko, Kuwata, Kiyoko, Yamaguchi, Haruka, Fukuoka, Masahiro, Nishio, Kazuto, Nakagawa, Kazuhiko
Published in Molecular cancer therapeutics (01.06.2010)
Published in Molecular cancer therapeutics (01.06.2010)
Get full text
Journal Article
TAK-701, a humanized monoclonal antibody to hepatocyte growth factor, reverses gefitinib resistance induced by tumor-derived HGF in non-small cell lung cancer with an EGFR mutation
Okamoto, Wataru, Okamoto, Isamu, Tanaka, Kaoru, Hatashita, Erina, Yamada, Yuki, Kuwata, Kiyoko, Yamaguchi, Haruka, Arao, Tokuzo, Nishio, Kazuto, Fukuoka, Masahiro, Jänne, Pasi A, Nakagawa, Kazuhiko
Published in Molecular cancer therapeutics (01.10.2010)
Published in Molecular cancer therapeutics (01.10.2010)
Get full text
Journal Article
Abstract 1844: Novel HER3 neutralizing antibody, patritumab abrogates cetuximab resistance mediated by a heregulin-autocrine loop in colorectal cancer
Kawakami, Hisato, Okamoto, Isamu, Yonesaka, Kimio, Okamoto, Kunio, Kuwata, Kiyoko, Morita, Yume, Yamaguchi, Haruka, Nishio, Kazuto, Nakagawa, Kazuhiko
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
Abstract 4657: MET amplification as a potential therapeutic target in gastric cancer
Kawakami, Hisato, Okamoto, Isamu, Arao, Tokuzo, Okamoto, Wataru, Matsumoto, Kazuko, Taniguchi, Hirokazu, Kuwata, Kiyoko, Yamaguchi, Haruka, Nishio, Kazuto, Nakagawa, Kazuhiko, Yamada, Yasuhide
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Get full text
Journal Article
Human papillomavirus DNA and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma
Kawakami, Hisato, Okamoto, Isamu, Terao, Kyoichi, Sakai, Kazuko, Suzuki, Minoru, Ueda, Shinya, Tanaka, Kaoru, Kuwata, Kiyoko, Morita, Yume, Ono, Koji, Nishio, Kazuto, Nishimura, Yasumasa, Doi, Katsumi, Nakagawa, Kazuhiko
Published in Cancer medicine (Malden, MA) (01.12.2013)
Published in Cancer medicine (Malden, MA) (01.12.2013)
Get full text
Journal Article
Abstract 5460: Identification of c-Src as a potential therapeutic target for gastric cancer and of MET activation as a cause of resistance to c-Src inhibition
Okamoto, Wataru, Okamoto, Isamu, Yoshida, Takeshi, Hatashita, Erina, Yamada, Yuki, Kuwata, Kiyoko, Arao, Tokuzo, Yanagihara, Kazuyoshi, Nishio, Kazuto, Fukuoka, Masahiro, Nakagawa, Kazuhiko
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Get full text
Journal Article
TAK-701, a humanized monoclonal antibody to HGF, reverses gefitinib resistance induced by tumor-derived HGF in non–small cell lung cancer with an EGFR mutation
Okamoto, Wataru, Okamoto, Isamu, Tanaka, Kaoru, Hatashita, Erina, Yamada, Yuki, Kuwata, Kiyoko, Yamaguchi, Haruka, Arao, Tokuzo, Nishio, Kazuto, Fukuoka, Masahiro, Jänne, Pasi A., Nakagawa, Kazuhiko
Published in Molecular cancer therapeutics (17.08.2010)
Published in Molecular cancer therapeutics (17.08.2010)
Get full text
Journal Article
Human papillomavirus DNA and p16 expression in J apanese patients with oropharyngeal squamous cell carcinoma
Kawakami, Hisato, Okamoto, Isamu, Terao, Kyoichi, Sakai, Kazuko, Suzuki, Minoru, Ueda, Shinya, Tanaka, Kaoru, Kuwata, Kiyoko, Morita, Yume, Ono, Koji, Nishio, Kazuto, Nishimura, Yasumasa, Doi, Katsumi, Nakagawa, Kazuhiko
Published in Cancer medicine (Malden, MA) (01.12.2013)
Published in Cancer medicine (Malden, MA) (01.12.2013)
Get full text
Journal Article