Natural product synthesis in the age of scalability
Kuttruff, Christian A, Eastgate, Martin D, Baran, Phil S
Published in Natural product reports (01.01.2014)
Published in Natural product reports (01.01.2014)
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Journal Article
Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer
Kuttruff, Christian A., Fleck, Martin, Carotta, Sebastian, Arnhof, Heribert, Bretschneider, Tom, Dahmann, Georg, Gremel, Gabriela, Grube, Achim, Handschuh, Sandra, Heimann, Annekatrin, Hofmann, Marco H., Impagnatiello, Maria A., Nar, Herbert, Rast, Georg, Schaaf, Otmar, Schmidt, Esther, Oost, Thorsten
Published in Journal of medicinal chemistry (27.07.2023)
Published in Journal of medicinal chemistry (27.07.2023)
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Journal Article
Late‐Stage Functionalization of Drug‐Like Molecules Using Diversinates
Kuttruff, Christian A., Haile, Margit, Kraml, Johannes, Tautermann, Christofer S.
Published in ChemMedChem (23.05.2018)
Published in ChemMedChem (23.05.2018)
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Journal Article
Real-time measurement of cellular bioenergetics in fully differentiated human nasal epithelial cells grown at air-liquid-interface
Mavin, Emily, Verdon, Bernard, Carrie, Sean, Saint-Criq, Vinciane, Powell, Jason, Kuttruff, Christian A, Ward, Chris, Garnett, James P, Miwa, Satomi
Published in American journal of physiology. Lung cellular and molecular physiology (01.06.2020)
Published in American journal of physiology. Lung cellular and molecular physiology (01.06.2020)
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Journal Article
Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis
Schruf, Eva, Schroeder, Victoria, Kuttruff, Christian A, Weigle, Sabine, Krell, Martin, Benz, Maryke, Bretschneider, Tom, Holweg, Alexander, Schuler, Michael, Frick, Manfred, Nicklin, Paul, Garnett, James P, Sobotta, Mirko C
Published in Respiratory research (09.05.2019)
Published in Respiratory research (09.05.2019)
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Journal Article
CH Oxidation of Ingenanes Enables Potent and Selective Protein Kinase C Isoform Activation
Jin, Yehua, Yeh, Chien-Hung, Kuttruff, Christian A., Jørgensen, Lars, Dünstl, Georg, Felding, Jakob, Natarajan, Swaminathan R., Baran, Phil S.
Published in Angewandte Chemie International Edition (16.11.2015)
Published in Angewandte Chemie International Edition (16.11.2015)
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Journal Article
Chemical Proteomics Identifies SLC25A20 as a Functional Target of the Ingenol Class of Actinic Keratosis Drugs
Parker, Christopher G, Kuttruff, Christian A, Galmozzi, Andrea, Jørgensen, Lars, Yeh, Chien-Hung, Hermanson, Daniel J, Wang, Yujia, Artola, Marta, McKerrall, Steven J, Josyln, Christopher M, Nørremark, Bjarne, Dünstl, Georg, Felding, Jakob, Saez, Enrique, Baran, Phil S, Cravatt, Benjamin F
Published in ACS central science (27.12.2017)
Published in ACS central science (27.12.2017)
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Journal Article
Evolution of a Synthetic Strategy for the Variecolortides
Kuttruff, Christian A., Mayer, Peter, Trauner, Dirk
Published in European journal of organic chemistry (01.09.2012)
Published in European journal of organic chemistry (01.09.2012)
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Journal Article
Development of a Concise Synthesis of (+)-Ingenol
McKerrall, Steven J, Jørgensen, Lars, Kuttruff, Christian A, Ungeheuer, Felix, Baran, Phil S
Published in Journal of the American Chemical Society (16.04.2014)
Published in Journal of the American Chemical Society (16.04.2014)
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Journal Article
Characterization of the properties of a selective, orally bioavailable autotaxin inhibitor in preclinical models of advanced stages of liver fibrosis
Baader, Manuel, Bretschneider, Tom, Broermann, Andre, Rippmann, Joerg F, Stierstorfer, Birgit, Kuttruff, Christian A, Mark, Michael
Published in British journal of pharmacology (01.02.2018)
Published in British journal of pharmacology (01.02.2018)
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Journal Article
Carbamoyl Anion Addition to Azirines
Kerner, Michael J, Kuttruff, Christian A, Chevliakov, Maxim, Buono, Frederic G, Gao, Donghong A, Krawiec, Mariusz, Busacca, Carl A, Senanayake, Chris H, Wipf, Peter, Reeves, Jonathan T
Published in Organic letters (04.06.2021)
Published in Organic letters (04.06.2021)
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Journal Article
Frontiers in Medicinal Chemistry 2022 Goes Virtual
Diamanti, Eleonora, Méndez, María, Ross, Tatjana, Kuttruff, Christian A., Lefranc, Julien, Klingler, Franca‐Maria, Nussbaum, Franz, Jung, Manfred, Gehringer, Matthias
Published in ChemMedChem (04.11.2022)
Published in ChemMedChem (04.11.2022)
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Journal Article
Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo
Kuttruff, Christian A, Ferrara, Marco, Bretschneider, Tom, Hoerer, Stefan, Handschuh, Sandra, Nosse, Bernd, Romig, Helmut, Nicklin, Paul, Roth, Gerald J
Published in ACS medicinal chemistry letters (14.12.2017)
Published in ACS medicinal chemistry letters (14.12.2017)
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Journal Article
An Approach to Aminonaphthoquinone Ansamycins Using a Modified Danishefsky Diene
Kuttruff, Christian A, Geiger, Simon, Cakmak, Mesut, Mayer, Peter, Trauner, Dirk
Published in Organic letters (17.02.2012)
Published in Organic letters (17.02.2012)
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Journal Article
Correction to “Development of a Concise Synthesis of (+)-Ingenol”
McKerrall, Steven J, Jørgensen, Lars, Kuttruff, Christian A, Ungeheuer, Felix, Baran, Phil S
Published in Journal of the American Chemical Society (18.11.2015)
Published in Journal of the American Chemical Society (18.11.2015)
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Journal Article
Prolonged stability by cyclization: Macrocyclic phosphino dipeptide isostere inhibitors of β-secretase (BACE1)
Huber, Timo, Manzenrieder, Florian, Kuttruff, Christian A., Dorner-Ciossek, Cornelia, Kessler, Horst
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Journal Article
Exploring the Pharmacology and Action Spectra of Photochromic Open-Channel Blockers
Fehrentz, Timm, Kuttruff, Christian A., Huber, Florian M. E., Kienzler, Michael A., Mayer, Peter, Trauner, Dirk
Published in Chembiochem : a European journal of chemical biology (13.08.2012)
Published in Chembiochem : a European journal of chemical biology (13.08.2012)
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Journal Article
Corrigendum: Exploring the Pharmacology and Action Spectra of Photochromic Open-Channel Blockers
Fehrentz, Timm, Kuttruff, Christian A., Huber, Florian M. E., Kienzler, Michael A., Mayer, Peter, Trauner, Dirk
Published in Chembiochem : a European journal of chemical biology (08.07.2013)
Published in Chembiochem : a European journal of chemical biology (08.07.2013)
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Journal Article