TransCon IL-2 β/γ, a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 analog, demonstrates improved pharmacokinetics and profound expansion of cytotoxic immune cells in non-human primates
Rosen, David, Månsson Kvarnhammar, Anne, Olling, Janne Damm, Laufer, Burkhardt, Knappe, Thomas, Karlsson, Jens Jakob, Kurpiers, Thomas, Zettler, Joachim, Runz, Josefine, Faltinger, Frank, Viet, Laura, Krusch, Mathias, Schnabel, Meike, Reich, Diana, Glock, Philipp, Singel, Stina Mui, Sprogøe, Kennett, Abel, Kristin Laura, Breinholt, Vibeke Miller, Punnonen, Juha
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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hGH NOVEL POLYMERIC HGH PRODRUGS
WEGGE THOMAS, EXNER EVELYN, KURPIERS THOMAS, RASMUSSEN GRETHE NRSKOV, SCHUBERT NINA, SPLANEMANN ANNA, ZETTLER JOACHIM, JENSEN STEEN, HERMANN ALINA, RAU HARALD, LESSMANN TORBEN
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
Patent
TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune cells for the treatment of cancer
Rosen, David B, Kvarnhammar, Anne Månsson, Laufer, Burkhardt, Knappe, Thomas, Karlsson, Jens Jakob, Hong, Enping, Lee, Yu-Chi, Thakar, Dhruv, Zúñiga, Luis Alejandro, Bang, Kathy, Sabharwal, Simran Singh, Uppal, Karan, Olling, Janne Damm, Kjaergaard, Kristian, Kurpiers, Thomas, Schnabel, Meike, Reich, Diana, Glock, Philipp, Zettler, Joachim, Krusch, Mathias, Bernhard, Ana, Heinig, Stefan, Konjik, Valentino, Wegge, Thomas, Hehn, Yvonne, Killian, Steffen, Viet, Laura, Runz, Josefine, Faltinger, Frank, Tabrizi, Mohammad, Abel, Kristin Laura, Breinholt, Vibeke Miller, Singel, Stina M, Sprogøe, Kennett, Punnonen, Juha
Published in Journal for immunotherapy of cancer (01.07.2022)
Published in Journal for immunotherapy of cancer (01.07.2022)
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Engineering Artificially Split Inteins for Applications in Protein Chemistry: Biochemical Characterization of the Split Ssp DnaB Intein and Comparison to the Split Sce VMA Intein
Brenzel, Steffen, Kurpiers, Thomas, Mootz, Henning D
Published in Biochemistry (Easton) (14.02.2006)
Published in Biochemistry (Easton) (14.02.2006)
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Journal Article
hGH NOVEL POLYMERIC HGH PRODRUGS
WEGGE THOMAS, EXNER EVELYN, KURPIERS THOMAS, SCHUBERT NINA, SPLANEMANN ANNA, RASMUSSEN GRETHE NØRSKOV, ZETTLER JOACHIM, JENSEN STEEN, HERMANN ALINA, RAU HARALD, LESSMANN TORBEN
Year of Publication 19.07.2017
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Year of Publication 19.07.2017
Patent