Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis
Stachtea, Xanthi N, Tykesson, Emil, van Kuppevelt, Toin H, Feinstein, Ricardo, Malmström, Anders, Reijmers, Rogier M, Maccarana, Marco
Published in PloS one (21.10.2015)
Published in PloS one (21.10.2015)
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Journal Article
Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions
Kalus, Ina, Rohn, Susanne, Puvirajesinghe, Tania M, Guimond, Scott E, Eyckerman-Kölln, Pieter J, Ten Dam, Gerdy, van Kuppevelt, Toin H, Turnbull, Jeremy E, Dierks, Thomas
Published in PloS one (08.10.2015)
Published in PloS one (08.10.2015)
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Journal Article
Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling
Takashima, Yasutoshi, Keino-Masu, Kazuko, Yashiro, Hiroshi, Hara, Satoshi, Suzuki, Tomo, van Kuppevelt, Toin H, Masu, Masayuki, Nagata, Michio
Published in American journal of physiology. Renal physiology (01.03.2016)
Published in American journal of physiology. Renal physiology (01.03.2016)
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Journal Article
Low-GDP, pH-neutral solutions preserve peritoneal endothelial glycocalyx during long-term peritoneal dialysis
Sugiyama, Naoya, Tawada, Mitsuhiro, Sun, Ting, Suzuki, Yasuhiro, Kinashi, Hiroshi, Yamaguchi, Makoto, Katsuno, Takayuki, Aten, Jan, Vlahu, Carmen A., van Kuppevelt, Toin H., Takei, Yoshifumi, Ishimoto, Takuji, Maruyama, Shoichi, Mizuno, Masashi, Ito, Yasuhiko
Published in Clinical and experimental nephrology (01.09.2021)
Published in Clinical and experimental nephrology (01.09.2021)
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Journal Article
Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
Christianson, Helena C., Svensson, Katrin J., van Kuppevelt, Toin H., Li, Jin-Ping, Belting, Mattias
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
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Journal Article
Chemotherapeutic drug delivery by tumoral extracellular matrix targeting
Raavé, René, van Kuppevelt, Toin H., Daamen, Willeke F.
Published in Journal of controlled release (28.03.2018)
Published in Journal of controlled release (28.03.2018)
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Journal Article
Dermatan Sulfate Is Involved in the Tumorigenic Properties of Esophagus Squamous Cell Carcinoma
THELIN, Martin A, SVENSSON, Katrin J, BELTING, Mattias, MACCARANA, Marco, MALMSTRÖM, Anders, XIAOFENG SHI, BAGHER, Mariam, AXELSSON, Jakob, ISINGER-EKSTRAND, Anna, KUPPEVELT, Toin H. Van, JOHANSSON, Jan, NILBERT, Mef, ZAIA, Joseph
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity
Lamanna, William C, Baldwin, Rebecca J, Padva, Michael, Kalus, Ina, Ten Dam, Gerdy, van Kuppevelt, Toin H, Gallagher, John T, von Figura, Kurt, Dierks, Thomas, Merry, Catherine L R
Published in Biochemical journal (15.11.2006)
Published in Biochemical journal (15.11.2006)
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Journal Article
Iduronic acid in chondroitin/dermatan sulfate affects directional migration of aortic smooth muscle cells
Bartolini, Barbara, Thelin, Martin A, Svensson, Lena, Ghiselli, Giancarlo, van Kuppevelt, Toin H, Malmström, Anders, Maccarana, Marco
Published in PloS one (02.07.2013)
Published in PloS one (02.07.2013)
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Journal Article
Differential Expression of Specific Dermatan Sulfate Domains in Renal Pathology
Lensen, Joost F M, van der Vlag, Johan, Versteeg, Elly M M, Wetzels, Jack F M, van den Heuvel, Lambert P W J, Berden, Jo H M, van Kuppevelt, Toin H, Rops, Angelique L W M M
Published in PloS one (31.08.2015)
Published in PloS one (31.08.2015)
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Journal Article
Evaluation and Refinement of Sample Preparation Methods for Extracellular Matrix Proteome Coverage
McCabe, Maxwell C., Schmitt, Lauren R., Hill, Ryan C., Dzieciatkowska, Monika, Maslanka, Mark, Daamen, Willeke F., van Kuppevelt, Toin H., Hof, Danique J., Hansen, Kirk C.
Published in Molecular & cellular proteomics (01.01.2021)
Published in Molecular & cellular proteomics (01.01.2021)
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Journal Article
Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx
Garsen, Marjolein, Lenoir, Olivia, Rops, Angelique L W M M, Dijkman, Henry B, Willemsen, Brigith, van Kuppevelt, Toin H, Rabelink, Ton J, Berden, Jo H M, Tharaux, Pierre-Louis, van der Vlag, Johan
Published in Journal of the American Society of Nephrology (01.12.2016)
Published in Journal of the American Society of Nephrology (01.12.2016)
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Journal Article
Hypoxic Induction of Exosome Uptake through Proteoglycan-Dependent Endocytosis Fuels the Lipid Droplet Phenotype in Glioma
Cerezo-Magaña, Myriam, Christianson, Helena C, van Kuppevelt, Toin H, Forsberg-Nilsson, Karin, Belting, Mattias
Published in Molecular cancer research (01.03.2021)
Published in Molecular cancer research (01.03.2021)
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Journal Article
Parietal epithelial cells participate in the formation of sclerotic lesions in focal segmental glomerulosclerosis
Smeets, Bart, Kuppe, Christoph, Sicking, Eva-Maria, Fuss, Astrid, Jirak, Peggy, van Kuppevelt, Toin H, Endlich, Karlhans, Wetzels, Jack F M, Gröne, Hermann-Josef, Floege, Jürgen, Moeller, Marcus J
Published in Journal of the American Society of Nephrology (01.07.2011)
Published in Journal of the American Society of Nephrology (01.07.2011)
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Journal Article
Interactions between Skeletal Muscle Myoblasts and their Extracellular Matrix Revealed by a Serum Free Culture System
Chaturvedi, Vishal, Dye, Danielle E, Kinnear, Beverley F, van Kuppevelt, Toin H, Grounds, Miranda D, Coombe, Deirdre R
Published in PloS one (01.06.2015)
Published in PloS one (01.06.2015)
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Journal Article
CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis
Eymael, Jennifer, Sharma, Shagun, Loeven, Markus A., Wetzels, Jack F., Mooren, Fieke, Florquin, Sandrine, Deegens, Jeroen K., Willemsen, Brigith K., Sharma, Vikram, van Kuppevelt, Toin H., Bakker, Marinka A., Ostendorf, Tammo, Moeller, Marcus J., Dijkman, Henry B., Smeets, Bart, van der Vlag, Johan
Published in Kidney international (01.03.2018)
Published in Kidney international (01.03.2018)
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Journal Article
Common histological patterns in glomerular epithelial cells in secondary focal segmental glomerulosclerosis
Kuppe, Christoph, Gröne, Hermann-Josef, Ostendorf, Tammo, van Kuppevelt, Toin H., Boor, Peter, Floege, Jürgen, Smeets, Bart, Moeller, Marcus J.
Published in Kidney international (01.11.2015)
Published in Kidney international (01.11.2015)
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Journal Article
Membrane permeation of arginine-rich cell-penetrating peptides independent of transmembrane potential as a function of lipid composition and membrane fluidity
Wallbrecher, Rike, Ackels, Tobias, Olea, R. Alis, Klein, Marco J., Caillon, Lucie, Schiller, Jürgen, Bovée-Geurts, Petra H., van Kuppevelt, Toin H., Ulrich, Anne S., Spehr, Marc, Adjobo-Hermans, Merel J.W., Brock, Roland
Published in Journal of controlled release (28.06.2017)
Published in Journal of controlled release (28.06.2017)
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