Discovery of 2,4-diamino-5-cyanopyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug-drug interactions
Kunikawa, Shigeki, Tanaka, Akira, Takasuna, Yuji, Tasaki, Mamoru, Chida, Noboru
Published in Bioorganic & medicinal chemistry (01.03.2019)
Published in Bioorganic & medicinal chemistry (01.03.2019)
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A novel 2,4-diaminopyrimidine derivative as selective inhibitor of protein kinase C theta prevents allograft rejection in a rat heart transplant model
Kunikawa, Shigeki, Tanaka, Akira, Takasuna, Yuji, Tasaki, Mamoru, Chida, Noboru
Published in Bioorganic & medicinal chemistry (01.11.2018)
Published in Bioorganic & medicinal chemistry (01.11.2018)
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Optimization of 2,4-diamino-5-fluoropyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug–drug interactions and P-gp liability
Kunikawa, Shigeki, Tanaka, Akira, Mukoyoshi, Koichiro, Nagashima, Shinya, Tominaga, Hiroaki, Chida, Noboru, Tasaki, Mamoru, Shirai, Fumiyuki
Published in Bioorganic & medicinal chemistry (01.07.2015)
Published in Bioorganic & medicinal chemistry (01.07.2015)
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Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3
Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (01.08.2015)
Published in Bioorganic & medicinal chemistry (01.08.2015)
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Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]
Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (15.05.2017)
Published in Bioorganic & medicinal chemistry (15.05.2017)
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Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]
Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (15.09.2016)
Published in Bioorganic & medicinal chemistry (15.09.2016)
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IMIDAZODIAZEPINE COMPOUND
MASUDA NAOYUKI, YARIMIZU JUNKO, KUNIKAWA SHIGEKI, MORITA MASATAKA, KAWAKAMI SHIMPEI, IMAIZUMI TOMOYOSHI
Year of Publication 09.02.2018
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Year of Publication 09.02.2018
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퀴나졸린 화합물
ARAKAWA KEISUKE, KURAMOTO KAZUYUKI, NIGAWARA TAKAHIRO, SHIMADA ITSURO, ABE TOMOAKI, SATAKE YOSHIKI, AKAIWA MICHINORI, SHIMAZAKI MASASHI, WATANABE KAZUSHI, ARAKI TAKANOBU, YAMAKI SUSUMU, KUNIKAWA SHIGEKI, KOIKE TAKANORI, IMAIZUMI TOMOYOSHI
Year of Publication 08.10.2019
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Year of Publication 08.10.2019
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IMIDAZODIAZEPINE COMPOUND
KAWAKAMI, Shimpei, MORITA, Masataka, IMAIZUMI, Tomoyoshi, MASUDA, Naoyuki, KUNIKAWA, Shigeki, YARIMIZU, Junko
Year of Publication 22.12.2016
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Year of Publication 22.12.2016
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QUINAZOLINE COMPOUND
ABE, Tomoaki, KURAMOTO, Kazuyuki, AKAIWA, Michinori, YAMAKI, Susumu, KOIKE, Takanori, SATAKE, Yoshiki, NIGAWARA, Takahiro, SHIMADA, Itsuro, IMAIZUMI, Tomoyoshi, ARAKI, Takanobu, ARAKAWA, Keisuke, WATANABE, Kazushi, SHIMAZAKI, Masashi, KUNIKAWA, Shigeki
Year of Publication 09.08.2018
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Year of Publication 09.08.2018
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테트라히드로옥세피노피리딘 화합물
SHISHIKURA JUNICHI, NAGASHIMA SHINYA, AOKI SATOSHI, YAMADA HIROSHI, TAMAKI KEISUKE, OGIYAMA TAKASHI, KOGANEMARU YOHEI, YONEZAWA KOICHI, SATO RYO, KAWAKAMI SHIMPEI, KAMIKAWA AKIO, KOIZUMI YUKA, KAKIMOTO SHUICHIROU, KUNIKAWA SHIGEKI, MIYAMOTO SATOSHI
Year of Publication 13.04.2018
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Year of Publication 13.04.2018
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Synthesis of Antimalarial Yingzhaosu A Analogues by the Peroxidation of Dienes with Co(II)/O2/Et3SiH
Tokuyasu, Takahiro, Kunikawa, Shigeki, Abe, Manabu, Masuyama, Araki, Nojima, Masatomo, Kim, Hye-Sook, Begum, Khurshida, Wataya, Yusuke
Published in Journal of organic chemistry (19.09.2003)
Published in Journal of organic chemistry (19.09.2003)
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TETRAHYDROOXEPINOPYRIDINE COMPOUND
OGIYAMA, Takashi, KOIZUMI, Yuka, MIYAMOTO, Satoshi, TAMAKI, Keisuke, SATO, Ryo, KAWAKAMI, Shimpei, YAMADA, Hiroshi, YONEZAWA, Koichi, NAGASHIMA, Shinya, KAMIKAWA, Akio, AOKI, Satoshi, KAKIMOTO, Shuichirou, KOGANEMARU, Yohei, KUNIKAWA, Shigeki, SHISHIKURA, Junichi
Year of Publication 23.02.2017
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Year of Publication 23.02.2017
Patent
2,4-DIAMINOPYRIMIDINE COMPOUND HAVING AMINOCYCLOHEXYLALKYL GROUP
TAKASUNA, YUJI, CHIDA, NOBORU, TANAKA, AKIRA, KUNIKAWA, SHIGEKI, MUKOYOSHI, KOICHIRO
Year of Publication 25.11.2010
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Year of Publication 25.11.2010
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Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution
Wu, Jin-Ming, Kunikawa, Shigeki, Tokuyasu, Takahiro, Masuyama, Araki, Nojima, Masatomo, Kim, Hye-Sook, Wataya, Yusuke
Published in Tetrahedron (17.10.2005)
Published in Tetrahedron (17.10.2005)
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2,4-DIAMINOPYRIMIDINE COMPOUND
CHIDA NOBORU, TANAKA AKIRA, NAGASHIMA SHINYA, MUKOYOSHI KOICHIRO, MAEDA JUN, KUNIKAWA SHIGEKI, TAKASUNA YUJI
Year of Publication 12.05.2011
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Year of Publication 12.05.2011
Patent