Chronic Administration of the Metastin/Kisspeptin Analog KISS1-305 or the Investigational Agent TAK-448 Suppresses Hypothalamic Pituitary Gonadal Function and Depletes Plasma Testosterone in Adult Male Rats
Matsui, Hisanori, Tanaka, Akira, Yokoyama, Kotaro, Takatsu, Yoshihiro, Ishikawa, Kaori, Asami, Taiji, Nishizawa, Naoki, Suzuki, Atsuko, Kumano, Satoshi, Terada, Michiko, Kusaka, Masami, Kitada, Chieko, Ohtaki, Tetsuya
Published in Endocrinology (Philadelphia) (01.11.2012)
Published in Endocrinology (Philadelphia) (01.11.2012)
Get full text
Journal Article
Expression of KiSS-1, a metastasis suppressor gene, in trophoblast giant cells of the rat placenta
Terao, Yasuko, Kumano, Satoshi, Takatsu, Yoshihiro, Hattori, Masahiko, Nishimura, Atsushi, Ohtaki, Tetsuya, Shintani, Yasushi
Published in Biochimica et biophysica acta (25.05.2004)
Published in Biochimica et biophysica acta (25.05.2004)
Get full text
Journal Article
Isolation and cDNA cloning of a novel Galanin-like peptide (GALP) from porcine hypothalamus
Ohtaki, T, Kumano, S, Ishibashi, Y, Ogi, K, Matsui, H, Harada, M, Kitada, C, Kurokawa, T, Onda, H, Fujino, M
Published in The Journal of biological chemistry (24.12.1999)
Published in The Journal of biological chemistry (24.12.1999)
Get full text
Journal Article
Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors
Masuda, Yasushi, Takatsu, Yoshihiro, Terao, Yasuko, Kumano, Satoshi, Ishibashi, Yoshihiro, Suenaga, Masato, Abe, Michiko, Fukusumi, Shoji, Watanabe, Takuya, Shintani, Yasushi, Yamada, Takao, Hinuma, Shuji, Inatomi, Nobuhiro, Ohtaki, Tetsuya, Onda, Haruo, Fujino, Masahiko
Published in Biochemical and biophysical research communications (26.04.2002)
Published in Biochemical and biophysical research communications (26.04.2002)
Get full text
Journal Article
A Short-Length Peptide YY Analogue with Anorectic Effect in Mice
Nishizawa, Naoki, Niida, Ayumu, Masuda, Yasushi, Kumano, Satoshi, Yokoyama, Kotaro, Hirabayashi, Hideki, Amano, Nobuyuki, Ohtaki, Tetsuya, Asami, Taiji
Published in ACS omega (31.05.2017)
Published in ACS omega (31.05.2017)
Get full text
Journal Article
Requirement for the Kinase Activity of Human DNA-Dependent Protein Kinase Catalytic Subunit in DNA Strand Break Rejoining
Kurimasa, Akihiro, Kumano, Satoshi, Boubnov, Nikolai V., Story, Michael D., Tung, Chang-Shung, Peterson, Scott R., Chen, David J.
Published in Molecular and Cellular Biology (01.05.1999)
Published in Molecular and Cellular Biology (01.05.1999)
Get full text
Journal Article
Distribution of Galanin-Like Peptide in the Rat Brain
Takatsu, Yoshihiro, Matsumoto, Hirokazu, Ohtaki, Tetsuya, Kumano, Satoshi, Kitada, Chieko, Onda, Haruo, Nishimura, Osamu, Fujino, Masahiko
Published in Endocrinology (Philadelphia) (01.04.2001)
Published in Endocrinology (Philadelphia) (01.04.2001)
Get full text
Journal Article
PEGylated neuromedin U-8 shows long-lasting anorectic activity and anti-obesity effect in mice by peripheral administration
Masuda, Yasushi, Kumano, Satoshi, Noguchi, Jiro, Sakamoto, Kotaro, Inooka, Hiroshi, Ohtaki, Tetsuya
Published in Peptides (New York, N.Y. : 1980) (01.08.2017)
Published in Peptides (New York, N.Y. : 1980) (01.08.2017)
Get full text
Journal Article
A PEGylated analog of short-length Neuromedin U with potent anorectic and anti-obesity effects
Inooka, Hiroshi, Sakamoto, Kotaro, Shinohara, Tokuyuki, Masuda, Yasushi, Terada, Michiko, Kumano, Satoshi, Yokoyama, Kotaro, Noguchi, Jiro, Nishizawa, Naoki, Kamiguchi, Hidenori, Fujita, Hisashi, Asami, Taiji, Takekawa, Shiro, Ohtaki, Tetsuya
Published in Bioorganic & medicinal chemistry (15.04.2017)
Published in Bioorganic & medicinal chemistry (15.04.2017)
Get full text
Journal Article
Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac‑d‑Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly Potent Testosterone-Suppressive Activity and Excellent Water Solubility
Nishizawa, Naoki, Takatsu, Yoshihiro, Kumano, Satoshi, Kiba, Atsushi, Ban, Junko, Tsutsumi, Shunichirou, Matsui, Hisanori, Matsumoto, Shin-ichi, Yamaguchi, Masashi, Ikeda, Yukihiro, Kusaka, Masami, Ohtaki, Tetsuya, Itoh, Fumio, Asami, Taiji
Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
Get full text
Journal Article
Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice
Nishizawa, Naoki, Niida, Ayumu, Adachi, Yusuke, Masuda, Yasushi, Kumano, Satoshi, Yokoyama, Kotaro, Asakawa, Tomoko, Hirabayashi, Hideki, Amano, Nobuyuki, Takekawa, Shiro, Ohtaki, Tetsuya, Asami, Taiji
Published in Bioorganic & medicinal chemistry letters (15.08.2017)
Published in Bioorganic & medicinal chemistry letters (15.08.2017)
Get full text
Journal Article
Highly potent antiobesity effect of a short-length peptide YY analog in mice
Nishizawa, Naoki, Niida, Ayumu, Adachi, Yusuke, Kanematsu-Yamaki, Yoko, Masuda, Yasushi, Kumano, Satoshi, Yokoyama, Kotaro, Noguchi, Yoko, Asakawa, Tomoko, Hirabayashi, Hideki, Amano, Nobuyuki, Takekawa, Shiro, Ohtaki, Tetsuya, Asami, Taiji
Published in Bioorganic & medicinal chemistry (15.10.2017)
Published in Bioorganic & medicinal chemistry (15.10.2017)
Get full text
Journal Article
Pharmacologic profiles of investigational kisspeptin/metastin analogues, TAK-448 and TAK-683, in adult male rats in comparison to the GnRH analogue leuprolide
Matsui, Hisanori, Masaki, Tsuneo, Akinaga, Yumiko, Kiba, Atsushi, Takatsu, Yoshihiro, Nakata, Daisuke, Tanaka, Akira, Ban, Junko, Matsumoto, Shin-ichi, Kumano, Satoshi, Suzuki, Atsuko, Ikeda, Yukihiro, Yamaguchi, Masashi, Watanabe, Tatsuya, Ohtaki, Tetsuya, Kusaka, Masami
Published in European journal of pharmacology (15.07.2014)
Published in European journal of pharmacology (15.07.2014)
Get full text
Journal Article
Antiobesity Effect of a Short-Length Peptide YY Analogue after Continuous Administration in Mice
Nishizawa, Naoki, Niida, Ayumu, Masuda, Yasushi, Kumano, Satoshi, Yokoyama, Kotaro, Hirabayashi, Hideki, Amano, Nobuyuki, Ohtaki, Tetsuya, Asami, Taiji
Published in ACS medicinal chemistry letters (08.06.2017)
Published in ACS medicinal chemistry letters (08.06.2017)
Get full text
Journal Article
Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH 2 (TAK-448), with Highly Potent Testosterone-Suppressive Activity and Excellent Water Solubility
Nishizawa, Naoki, Takatsu, Yoshihiro, Kumano, Satoshi, Kiba, Atsushi, Ban, Junko, Tsutsumi, Shunichirou, Matsui, Hisanori, Matsumoto, Shin-Ichi, Yamaguchi, Masashi, Ikeda, Yukihiro, Kusaka, Masami, Ohtaki, Tetsuya, Itoh, Fumio, Asami, Taiji
Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
Get full text
Journal Article