Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling
Myeku, Natura, Clelland, Catherine L, Emrani, Sheina, Kukushkin, Nikolay V, Yu, Wai Haung, Goldberg, Alfred L, Duff, Karen E
Published in Nature medicine (01.01.2016)
Published in Nature medicine (01.01.2016)
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Journal Article
Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates
Besche, Henrike C, Sha, Zhe, Kukushkin, Nikolay V, Peth, Andreas, Hock, Eva-Maria, Kim, Woong, Gygi, Steven, Gutierrez, Juan A, Liao, Hua, Dick, Lawrence, Goldberg, Alfred L
Published in The EMBO journal (16.05.2014)
Published in The EMBO journal (16.05.2014)
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Journal Article
cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins
Lokireddy, Sudarsanareddy, Kukushkin, Nikolay Vadimovich, Goldberg, Alfred Lewis
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2015)
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Journal Article
Solid Xenon Carrier Based on α-Cyclodextrin: Properties, Preparation, and Application
Prokhorov, Dmitry A., Kutyshenko, Victor P., Tarahovsky, Yury S., Kukushkin, Nikolay I., Khrenov, Maxim O., Kovtun, Anatoly L., Zakharova, Nadezhda M.
Published in Journal of pharmaceutical sciences (01.01.2023)
Published in Journal of pharmaceutical sciences (01.01.2023)
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Journal Article
Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins
Alonzi, Dominic S, Kukushkin, Nikolay V, Allman, Sarah A, Hakki, Zalihe, Williams, Spencer J, Pierce, Lorna, Dwek, Raymond A, Butters, Terry D
Published in Cellular and molecular life sciences : CMLS (01.08.2013)
Published in Cellular and molecular life sciences : CMLS (01.08.2013)
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Journal Article
Increased Autolysis of μ‐Calpain in Skeletal Muscles of Chronic Alcohol‐Fed Rats
Gritsyna, Yulia V., Salmov, Nikolay N., Bobylev, Alexander G., Ulanova, Anna D., Kukushkin, Nikolay I., Podlubnaya, Zoya A., Vikhlyantsev, Ivan M.
Published in Alcoholism, clinical and experimental research (01.10.2017)
Published in Alcoholism, clinical and experimental research (01.10.2017)
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Journal Article
Restricted processing of glycans by endomannosidase in mammalian cells
Kukushkin, Nikolay V, Easthope, Iona S, Alonzi, Dominic S, Butters, Terry D
Published in Glycobiology (Oxford) (01.10.2012)
Published in Glycobiology (Oxford) (01.10.2012)
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Journal Article
Reversion of Structure-Activity Relationships of Antitumor Platinum Complexes by Acetoxime but Not Hydroxylamine Ligands
Zorbas-Seifried, Stefanie, Jakupec, Michael A, Kukushkin, Nikolay V, Groessl, Michael, Hartinger, Christian G, Semenova, Olga, Zorbas, Haralabos, Kukushkin, Vadim Yu, Keppler, Bernhard K
Published in Molecular pharmacology (01.01.2007)
Published in Molecular pharmacology (01.01.2007)
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Journal Article
Non-specific accumulation of glycosphingolipids in GNE myopathy
Patzel, Katherine A., Yardeni, Tal, Le Poëc-Celic, Erell, Leoyklang, Petcharat, Dorward, Heidi, Alonzi, Dominic S., Kukushkin, Nikolay V., Xu, Bixue, Zhang, Yongmin, Sollogoub, Matthieu, Blériot, Yves, Gahl, William A., Huizing, Marjan, Butters, Terry D.
Published in Journal of inherited metabolic disease (01.03.2014)
Published in Journal of inherited metabolic disease (01.03.2014)
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Journal Article
Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells
Butters, Terry D, Alonzi, Dominic S, Kukushkin, Nikolay V, Ren, Yuan, Blériot, Yves
Published in Glycoconjugate journal (01.12.2009)
Published in Glycoconjugate journal (01.12.2009)
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Journal Article
Memory Takes Time
Kukushkin, Nikolay Vadimovich, Carew, Thomas James
Published in Neuron (Cambridge, Mass.) (19.07.2017)
Published in Neuron (Cambridge, Mass.) (19.07.2017)
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Journal Article
Neurotropic and modulatory effects of insulin-like growth factor II in Aplysia
Kukushkin, Nikolay Vadimovich, Williams, Sidney Paulina, Carew, Thomas James
Published in Scientific reports (07.10.2019)
Published in Scientific reports (07.10.2019)
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Journal Article
The chemical structure of triblock copolymers and the adsorption capacity of perfluorocarbon—core nanoparticles stabilized by them
Zhalimov, Vitaly, Sklifas, Alla, Kaptsov, Vladimir, Penkov, Nikita, Temnov, Andrey, Kukushkin, Nikolay
Published in Colloid and polymer science (01.02.2018)
Published in Colloid and polymer science (01.02.2018)
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Journal Article
Thiostrepton interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates
Sandu, Cristinel, Chandramouli, Nagaranjan, Glickman, Joseph Fraser, Molina, Henrik, Kuo, Chueh‐Ling, Kukushkin, Nikolay, Goldberg, Alfred L., Steller, Hermann
Published in Journal of cellular and molecular medicine (01.09.2015)
Published in Journal of cellular and molecular medicine (01.09.2015)
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Journal Article
Fleetamine (3-O-α-d-glucopyranosyl-swainsonine): the synthesis of a hypothetical inhibitor of endo-α-mannosidase
Quach, Tim, Tsegay, Sammi, Thompson, Andrew J., Kukushkin, Nikolay V., Alonzi, Dominic S., Butters, Terry D., Davies, Gideon J., Williams, Spencer J.
Published in Tetrahedron: asymmetry (15.07.2012)
Published in Tetrahedron: asymmetry (15.07.2012)
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