Structure and Function of CutC Choline Lyase from Human Microbiota Bacterium Klebsiella pneumoniae
Kalnins, Gints, Kuka, Janis, Grinberga, Solveiga, Makrecka-Kuka, Marina, Liepinsh, Edgars, Dambrova, Maija, Tars, Kaspars
Published in The Journal of biological chemistry (28.08.2015)
Published in The Journal of biological chemistry (28.08.2015)
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Metformin decreases bacterial trimethylamine production and trimethylamine N-oxide levels in db/db mice
Kuka, Janis, Videja, Melita, Makrecka-Kuka, Marina, Liepins, Janis, Grinberga, Solveiga, Sevostjanovs, Eduards, Vilks, Karlis, Liepinsh, Edgars, Dambrova, Maija
Published in Scientific reports (03.09.2020)
Published in Scientific reports (03.09.2020)
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Pharmacological activation of PPARβ/δ preserves mitochondrial respiratory function in ischemia/reperfusion via stimulation of fatty acid oxidation-linked respiration and PGC-1α/NRF-1 signaling
Papatheodorou, Ioanna, Makrecka-Kuka, Marina, Kuka, Janis, Liepinsh, Edgars, Dambrova, Maija, Lazou, Antigone
Published in Frontiers in endocrinology (Lausanne) (15.08.2022)
Published in Frontiers in endocrinology (Lausanne) (15.08.2022)
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Empagliflozin Protects Cardiac Mitochondrial Fatty Acid Metabolism in a Mouse Model of Diet-Induced Lipid Overload
Makrecka-Kuka, Marina, Korzh, Stanislava, Videja, Melita, Vilks, Karlis, Cirule, Helena, Kuka, Janis, Dambrova, Maija, Liepinsh, Edgars
Published in Cardiovascular drugs and therapy (01.12.2020)
Published in Cardiovascular drugs and therapy (01.12.2020)
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Journal Article
SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function
Gautam, Mukesh, Genç, Barış, Helmold, Benjamin, Ahrens, Angela, Kuka, Janis, Makrecka-Kuka, Marina, Günay, Aksu, Koçak, Nuran, Aguilar-Wickings, Izaak R., Keefe, Dennis, Zheng, Guozhu, Swaminathan, Suchitra, Redmon, Martin, Zariwala, Hatim A., Özdinler, P. Hande
Published in Neurobiology of disease (01.03.2023)
Published in Neurobiology of disease (01.03.2023)
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Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis
Becker, Katja, Cao, Sha, Nilsson, Anna, Erlandsson, Maria, Hotop, Sven-Kevin, Kuka, Janis, Hansen, Jon, Haldimann, Klara, Grinberga, Solveiga, Berruga-Fernández, Talia, Huseby, Douglas L., Shariatgorji, Reza, Lindmark, Evelina, Platzack, Björn, Böttger, Erik C., Crich, David, Friberg, Lena E., Vingsbo Lundberg, Carina, Hughes, Diarmaid, Brönstrup, Mark, Andrén, Per E., Liepinsh, Edgars, Hobbie, Sven N.
Published in EBioMedicine (01.11.2021)
Published in EBioMedicine (01.11.2021)
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Journal Article
Expression and purification of active, stabilized trimethyllysine hydroxylase
Kazaks, Andris, Makrecka-Kuka, Marina, Kuka, Janis, Voronkova, Tatyana, Akopjana, Inara, Grinberga, Solveiga, Pugovics, Osvalds, Tars, Kaspars
Published in Protein expression and purification (01.12.2014)
Published in Protein expression and purification (01.12.2014)
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Journal Article
Excretion of the Polymyxin Derivative NAB739 in Murine Urine
Vaara, Martti, Vaara, Timo, Kuka, Janis, Sevostjanovs, Eduards, Grinberga, Solveiga, Dambrova, Maija, Liepinsh, Edgars
Published in Antibiotics (Basel) (27.03.2020)
Published in Antibiotics (Basel) (27.03.2020)
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Journal Article
Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart
Liepinsh, Edgars, Vilskersts, Reinis, Skapare, Elina, Svalbe, Baiba, Kuka, Janis, Cirule, Helena, Pugovics, Osvalds, Kalvinsh, Ivars, Dambrova, Maija
Published in Life sciences (1973) (24.10.2008)
Published in Life sciences (1973) (24.10.2008)
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Journal Article
Crystal structure of human gamma-butyrobetaine hydroxylase
Tars, Kaspars, Rumnieks, Janis, Zeltins, Andris, Kazaks, Andris, Kotelovica, Svetlana, Leonciks, Ainars, Sharipo, Jelena, Viksna, Arturs, Kuka, Janis, Liepinsh, Edgars, Dambrova, Maija
Published in Biochemical and biophysical research communications (06.08.2010)
Published in Biochemical and biophysical research communications (06.08.2010)
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Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials
Dambrova, Maija, Makrecka-Kuka, Marina, Kuka, Janis, Vilskersts, Reinis, Nordberg, Didi, Attwood, Misty M., Smesny, Stefan, Sen, Zumrut Duygu, Guo, An Chi, Oler, Eponine, Tian, Siyang, Zheng, Jiamin, Wishart, David S., Liepinsh, Edgars, Schiöth, Helgi B.
Published in Pharmacological reviews (01.07.2022)
Published in Pharmacological reviews (01.07.2022)
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Journal Article
Synthetic Access to Fluorocyclopropylidenes
Melngaile, Renate, Videja, Melita, Kuka, Janis, Kinens, Artis, Zacs, Dzintars, Veliks, Janis
Published in Organic letters (07.04.2023)
Published in Organic letters (07.04.2023)
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Journal Article
Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues
Makrecka-Kuka, Marina, Sevostjanovs, Eduards, Vilks, Karlis, Volska, Kristine, Antone, Unigunde, Kuka, Janis, Makarova, Elina, Pugovics, Osvalds, Dambrova, Maija, Liepinsh, Edgars
Published in Scientific reports (13.12.2017)
Published in Scientific reports (13.12.2017)
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Journal Article
Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria
Liepinsh, Edgars, Makrecka-Kuka, Marina, Volska, Kristine, Kuka, Janis, Makarova, Elina, Antone, Unigunde, Sevostjanovs, Eduards, Vilskersts, Reinis, Strods, Arnis, Tars, Kaspars, Dambrova, Maija
Published in Biochemical journal (01.05.2016)
Published in Biochemical journal (01.05.2016)
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Journal Article
Low cardiac content of long-chain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced mitochondrial and cardiac damage
Liepinsh, Edgars, Kuka, Janis, Vilks, Karlis, Svalbe, Baiba, Stelfa, Gundega, Vilskersts, Reinis, Sevostjanovs, Eduards, Goldins, Niks Ricards, Groma, Valerija, Grinberga, Solveiga, Plaas, Mario, Makrecka-Kuka, Marina, Dambrova, Maija
Published in Free radical biology & medicine (01.12.2021)
Published in Free radical biology & medicine (01.12.2021)
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Journal Article
Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation
Kuka, Janis, Liepinsh, Edgars, Makrecka-Kuka, Marina, Liepins, Janis, Cirule, Helena, Gustina, Daina, Loza, Einars, Zharkova-Malkova, Olga, Grinberga, Solveiga, Pugovics, Osvalds, Dambrova, Maija
Published in Life sciences (1973) (11.11.2014)
Published in Life sciences (1973) (11.11.2014)
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Journal Article
Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance
Liepinsh, Edgars, Makrecka-Kuka, Marina, Makarova, Elina, Volska, Kristine, Svalbe, Baiba, Sevostjanovs, Eduards, Grinberga, Solveiga, Kuka, Janis, Dambrova, Maija
Published in Pharmacological research (01.11.2016)
Published in Pharmacological research (01.11.2016)
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