Selected by bioinformatics and molecular docking analysis, Dhea and 2-14,15-Eg are effective against cholangiocarcinoma
Qin, Lei, Kuai, Jun, Yang, Fang, Yang, Lu, Sun, Peisheng, Zhang, Lanfang, Li, Guangpeng
Published in PloS one (03.02.2022)
Published in PloS one (03.02.2022)
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Upregulation of miR-199a/b contributes to cisplatin resistance via Wnt/β-catenin-ABCG2 signaling pathway in ALDHA1+ colorectal cancer stem cells
Chen, Binghe, Zhang, Dezhong, Kuai, Jun, Cheng, Mingkun, Fang, Xiangjie, Li, Guangyan
Published in Tumor biology (01.06.2017)
Published in Tumor biology (01.06.2017)
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High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections
Zhang, Lixin, Yan, Kezhi, Zhang, Yu, Huang, Ren, Bian, Jiang, Zheng, Chuansen, Sun, Haixiang, Chen, Zhihui, Sun, Nuo, An, Rong, Min, Fangui, Zhao, Weibo, Zhuo, Ying, You, Jianlan, Song, Yongjie, Yu, Zhenyan, Liu, Zhiheng, Yang, Keqian, Gao, Hong, Dai, Huanqin, Zhang, Xiaoli, Wang, Jian, Fu, Chengzhang, Pei, Gang, Liu, Jintao, Zhang, Si, Goodfellow, Michael, Jiang, Yuanying, Kuai, Jun, Zhou, Guochun, Chen, Xiaoping
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2007)
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Journal Article
Exploring novel bioactive compounds from marine microbes
Zhang, Lixin, An, Rong, Wang, Jinping, Sun, Nuo, Zhang, Si, Hu, Jiangchun, Kuai, Jun
Published in Current opinion in microbiology (01.06.2005)
Published in Current opinion in microbiology (01.06.2005)
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Journal Article
55 Exploring proximal biomarkers of CBL-B inhibition in human peripheral blood mononuclear cells
Greco, David, Qi, Yilin, Kuai, Jun, Jaeger, Samira, Bi, Yingzhi, Sun, Huadong, Liu, Wei, Carson, Ken, Reilly, Timothy, Harriman, Geraldine, Wang, Fang, Danaee, Hadi
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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864 Identification of a novel allosteric oral Cbl-b inhibitor that augmented T cell response and enhanced NK cell killing in vitro and in vivo
Kuai, Jun, Bi, Yingzhi, Qi, Yilin, Conrady, Deborah, Govindaraj, Rajiv, Hone, Graham, Aldrin Denny, R, Carson, Ken, Harriman, Geraldine, Wang, Fang
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines
Kuai, Jun, Gregory, Bernard, Hill, Andrew, Pittman, Debra D., Feldman, Jeffrey L., Brown, Tom, Carito, Brenda, O’Toole, Margot, Ramsey, Renee, Adolfsson, Oskar, Shields, Kathleen M., Dower, Ken, Hall, J. Perry, Kurdi, Yahya, Beech, Jonathan T., Nanchahal, Jagdeep, Feldmann, Marc, Foxwell, Brian M., Brennan, Fionula M., Winkler, David G., Lin, Lih-Ling
Published in Rheumatology (Oxford, England) (01.11.2009)
Published in Rheumatology (Oxford, England) (01.11.2009)
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Journal Article
An allosteric mechanism for potent inhibition of human ATP-citrate lyase
Wei, Jia, Leit, Silvana, Kuai, Jun, Therrien, Eric, Rafi, Salma, Harwood, H. James, DeLaBarre, Byron, Tong, Liang
Published in Nature (London) (01.04.2019)
Published in Nature (London) (01.04.2019)
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Journal Article
On-Chip Trust Evaluation Utilizing TDC-Based Parameter-Adjustable Security Primitive
Ma, Haocheng, He, Jiaji, Liu, Yanjiang, Kuai, Jun, Li, He, Liu, Leibo, Zhao, Yiqiang
Published in IEEE transactions on computer-aided design of integrated circuits and systems (01.10.2021)
Published in IEEE transactions on computer-aided design of integrated circuits and systems (01.10.2021)
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Journal Article
Effects of Activated ADP-ribosylation Factors on Golgi Morphology Require neither Activation of Phospholipase D1 nor Recruitment of Coatomer
Kuai, Jun, Boman, Annette L., Arnold, Rebecca S., Zhu, Xinjun, Kahn, Richard A.
Published in The Journal of biological chemistry (11.02.2000)
Published in The Journal of biological chemistry (11.02.2000)
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Journal Article
Discovery of Novel, First-in-Class Allosteric Modulators of MALT1 Scaffolding Function with Differentiated Pharmacology for NFκB-Driven Malignancies
Yao, Yi, Bi, Yingzhi, Sun, Huadong, Ling, Kevin, Xia, Huili, Kuai, Jun, DePaolo, Patrick, Lafont, Virginie, Diller, David, Aslanian, Ara, Jaeger, Samira, Wahle, Joe, Liu, Wei, Carson, Ken, Reilly, Timothy, Harriman, Gerry, Wang, Fang
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Effectors Increase the Affinity of ADP-ribosylation Factor for GTP to Increase Binding
Zhu, Xinjun, Boman, Annette L., Kuai, Jun, Cieplak, Witold, Kahn, Richard A.
Published in The Journal of biological chemistry (05.05.2000)
Published in The Journal of biological chemistry (05.05.2000)
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Computational study on novel natural compound inhibitor targeting IDH1_R132H
Zhou, Baolin, Yang, Fang, Qin, Lei, Kuai, Jun, Yang, Lu, Zhang, Lanfang, Sun, Peisheng, Li, Guangpeng, Wang, Xinhui
Published in Aging (Albany, NY.) (15.07.2022)
Published in Aging (Albany, NY.) (15.07.2022)
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Journal Article
Cryo-EM structure of human ATP-citrate lyase in complex with a potent inhibitor
Wei, Jia, Leit, Silvana, Kuai, Jun, Therrien, Eric, Rafi, Salma, Harwood Jr, H. James, DeLaBarre, Byron, Tong, Liang
Published in Acta crystallographica. Section A, Foundations and advances (20.07.2019)
Published in Acta crystallographica. Section A, Foundations and advances (20.07.2019)
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Journal Article
Abstract LB337: Inhibition of the E3 ligase CBL-B enhances the effector function and proliferation of natural killer cells
Qi, Yilin, Kuai, Jun, Bi, Yingzhi, Greco, David, Jaeger, Samira, Carson, Ken, Danaee, Hadi, Reilly, Timothy, Harriman, Geraldine, Wang, Fang
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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1354 CBL-B inhibition showed differentiated effects in a mixed lymphocyte reaction versus other immuno-oncology targeted approaches
Qi, Yilin, Kuai, Jun, Bi, Yingzhi, Sun, Huadong, Greco, David, Carson, Ken, Reilly, Timothy, Harriman, Geraldine, Wang, Fang
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)‑B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor‑β
Kuai, Jun, Mosyak, Lidia, Brooks, Jon, Cain, Michael, Carven, Gregory J, Ogawa, Shinji, Ishino, Tetsuya, Tam, May, Lavallie, Edward R, Yang, Zhiyong, Ponsel, Dirk, Rauchenberger, Robert, Arch, Robert, Pullen, Nick
Published in Biochemistry (Easton) (17.03.2015)
Published in Biochemistry (Easton) (17.03.2015)
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Abstract 598: A novel allosteric CBL-B inhibitor with differentiated immune enhancing activity in preclinical models
Qi, Yilin, Kuai, Jun, Bi, Yingzhi, Sun, Huadong, Conrady, Deborah G., Govindaraj, Rajiv G., Hone, Graham, Denny, Rajiah A., Carson, Ken, Reilly, Timothy, Harriman, Geraldine, Wang, Fang
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-α production in a receptor for advanced glycation end product-dependent manner
Ruan, Benfang Helen, Li, Xin, Winkler, Aaron R, Cunningham, Kristina M, Kuai, Jun, Greco, Rita M, Nocka, Karl H, Fitz, Lori J, Wright, Jill F, Pittman, Debra D, Tan, Xiang-Yang, Paulsen, Janet E, Lin, Lih Ling, Winkler, David G
Published in The Journal of immunology (1950) (01.10.2010)
Published in The Journal of immunology (1950) (01.10.2010)
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Investigation on Matrix Effects in Silicate Minerals by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry: Investigation on Matrix Effects in Silicate Minerals by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry
YUAN, Ji-Hai, ZHAN, Xiu-Chun, SUN, Dong-Yang, ZHAO, Ling-Hao, FAN, Chen-Zi, KUAI, Li-Jun, HU, Ming-Yue
Published in Fēnxī huàxué (01.10.2011)
Published in Fēnxī huàxué (01.10.2011)
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