Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
Feng, Xiaodong, Degese, Maria Sol, Iglesias-Bartolome, Ramiro, Vaque, Jose P., Molinolo, Alfredo A., Rodrigues, Murilo, Zaidi, M. Raza, Ksander, Bruce R., Merlino, Glenn, Sodhi, Akrit, Chen, Qianming, Gutkind, J. Silvio
Published in Cancer cell (16.06.2014)
Published in Cancer cell (16.06.2014)
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Retinal microglia initiate neuroinflammation in ocular autoimmunity
Okunuki, Yoko, Mukai, Ryo, Nakao, Takeshi, Tabor, Steven J., Butovsky, Oleg, Dana, Reza, Ksander, Bruce R., Connor, Kip M.
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
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A Genome-wide RNAi Screen Reveals a Trio-Regulated Rho GTPase Circuitry Transducing Mitogenic Signals Initiated by G Protein-Coupled Receptors
Vaqué, Jose P., Dorsam, Robert T., Feng, Xiaodong, Iglesias-Bartolome, Ramiro, Forsthoefel, David J., Chen, Qianming, Debant, Anne, Seeger, Mark A., Ksander, Bruce R., Teramoto, Hidemi, Gutkind, J. Silvio
Published in Molecular cell (10.01.2013)
Published in Molecular cell (10.01.2013)
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Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment
Okunuki, Yoko, Mukai, Ryo, Pearsall, Elizabeth A., Klokman, Garrett, Husain, Deeba, Park, Dong-Ho, Korobkina, Ekaterina, Weiner, Howard L., Butovsky, Oleg, Ksander, Bruce R., Miller, Joan W., Connor, Kip M.
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2018)
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NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration
Tseng, Wen Allen, Thein, Thuzar, Kinnunen, Kati, Lashkari, Kameran, Gregory, Meredith S, D'Amore, Patricia A, Ksander, Bruce R
Published in Investigative ophthalmology & visual science (07.01.2013)
Published in Investigative ophthalmology & visual science (07.01.2013)
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Reprogramming to recover youthful epigenetic information and restore vision
Lu, Yuancheng, Brommer, Benedikt, Tian, Xiao, Krishnan, Anitha, Meer, Margarita, Wang, Chen, Vera, Daniel L., Zeng, Qiurui, Yu, Doudou, Bonkowski, Michael S., Yang, Jae-Hyun, Zhou, Songlin, Hoffmann, Emma M., Karg, Margarete M., Schultz, Michael B., Kane, Alice E., Davidsohn, Noah, Korobkina, Ekaterina, Chwalek, Karolina, Rajman, Luis A., Church, George M., Hochedlinger, Konrad, Gladyshev, Vadim N., Horvath, Steve, Levine, Morgan E., Gregory-Ksander, Meredith S., Ksander, Bruce R., He, Zhigang, Sinclair, David A.
Published in Nature (London) (03.12.2020)
Published in Nature (London) (03.12.2020)
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Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma
Krishnan, Anitha, Fei, Fei, Jones, Alexander, Busto, Patricia, Marshak-Rothstein, Ann, Ksander, Bruce R, Gregory-Ksander, Meredith
Published in The Journal of immunology (1950) (15.12.2016)
Published in The Journal of immunology (1950) (15.12.2016)
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Microglia Prevent the Loss of Visual Function in the Aging Retina by Maintaining the Health of Retinal Pigment Epithelial Cells
Karg, Margarete M, Moorefield, May, Hoffmann, Emma, Shu, Daisy, Krasniqi, Drenushe, Philipose, Hannah, Ksander, Bruce R, Saint-Geniez, Magali
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis
Gregory-Ksander, Meredith, Perez, Victor L., Marshak-Rothstein, Ann, Ksander, Bruce R.
Published in Experimental eye research (01.02.2019)
Published in Experimental eye research (01.02.2019)
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ABCB5 is a limbal stem cell gene required for corneal development and repair
Ksander, Bruce R., Kolovou, Paraskevi E., Wilson, Brian J., Saab, Karim R., Guo, Qin, Ma, Jie, McGuire, Sean P., Gregory, Meredith S., Vincent, William J. B., Perez, Victor L., Cruz-Guilloty, Fernando, Kao, Winston W. Y., Call, Mindy K., Tucker, Budd A., Zhan, Qian, Murphy, George F., Lathrop, Kira L., Alt, Clemens, Mortensen, Luke J., Lin, Charles P., Zieske, James D., Frank, Markus H., Frank, Natasha Y.
Published in Nature (London) (17.07.2014)
Published in Nature (London) (17.07.2014)
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Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 Targeting
Ventin, Marco, Cattaneo, Giulia, Arya, Shahrzad, Jia, Jingyu, Gelmi, Maria C, Sun, Yi, Maggs, Luke, Ksander, Bruce R, Verdijk, Robert M, Boland, Genevieve M, Jenkins, Russell W, Haq, Rizwan, Jager, Martine J, Wang, Xinhui, Ryeom, Sandra, Ferrone, Cristina R
Published in Clinical cancer research (01.08.2024)
Published in Clinical cancer research (01.08.2024)
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Opposing roles for membrane bound and soluble Fas ligand in glaucoma-associated retinal ganglion cell death
Gregory, Meredith S, Hackett, Caroline G, Abernathy, Emma F, Lee, Karen S, Saff, Rebecca R, Hohlbaum, Andreas M, Moody, Krishna-Sulayman L, Hobson, Maura W, Jones, Alexander, Kolovou, Paraskevi, Karray, Saoussen, Giani, Andrea, John, Simon W M, Chen, Dong Feng, Marshak-Rothstein, Ann, Ksander, Bruce R
Published in PloS one (29.03.2011)
Published in PloS one (29.03.2011)
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Anti-Inflammatory and Anti-(Lymph)angiogenic Properties of an ABCB5+ Limbal Mesenchymal Stem Cell Population
Meshko, Berbang, Volatier, Thomas L A, Mann, Johanna, Kluth, Mark A, Ganss, Christoph, Frank, Markus H, Frank, Natasha Y, Ksander, Bruce R, Cursiefen, Claus, Notara, Maria
Published in International journal of molecular sciences (01.09.2024)
Published in International journal of molecular sciences (01.09.2024)
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Protein and mRNA Expression in Uveal Melanoma Cell Lines Are Related to GNA and BAP1 Mutation Status
Gelmi, Maria Chiara, de Ru, Arnoud H, van Veelen, Peter A, Tjokrodirijo, Rayman T N, Stern, Marc-Henri, Houy, Alexandre, Verdijk, Robert M, Vu, T H Khanh, Ksander, Bruce R, Vaarwater, Jolanda, Kilic, Emine, Brosens, Erwin, Jager, Martine J
Published in Investigative ophthalmology & visual science (23.07.2024)
Published in Investigative ophthalmology & visual science (23.07.2024)
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Modeling of human uveal melanoma in zebrafish xenograft embryos
van der Ent, Wietske, Burrello, Claudia, Teunisse, Amina F A S, Ksander, Bruce R, van der Velden, Pieter A, Jager, Martine J, Jochemsen, Aart G, Snaar-Jagalska, B Ewa
Published in Investigative ophthalmology & visual science (23.09.2014)
Published in Investigative ophthalmology & visual science (23.09.2014)
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The Role of Epigenetics in Accelerated Aging: A Reconsideration of Later-Life Visual Loss After Early Optic Neuropathy
Rizzo, 3rd, Joseph F, Shah, Madhura P, Krasniqi, Drenushe, Lu, Yuancheng Ryan, Sinclair, David A, Ksander, Bruce R
Published in Journal of neuro-ophthalmology (01.03.2024)
Published in Journal of neuro-ophthalmology (01.03.2024)
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Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions
Zahr, Alisar, Alcaide, Pilar, Yang, Jinling, Jones, Alexander, Gregory, Meredith, dela Paz, Nathaniel G., Patel-Hett, Sunita, Nevers, Tania, Koirala, Adarsha, Luscinskas, Francis W., Saint-Geniez, Magali, Ksander, Bruce, D’Amore, Patricia A., Argüeso, Pablo
Published in Nature communications (02.02.2016)
Published in Nature communications (02.02.2016)
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