Challenges in Transitioning Cocrystals from Bench to Bedside: Dissociation in Prototype Drug Product Environment
Koranne, Sampada, Sahoo, Anasuya, Krzyzaniak, Joseph F, Luthra, Suman, Arora, Kapildev K, Suryanarayanan, Raj
Published in Molecular pharmaceutics (06.08.2018)
Published in Molecular pharmaceutics (06.08.2018)
Get full text
Journal Article
Cocrystal Dissociation under Controlled Humidity: A Case Study of Caffeine–Glutaric Acid Cocrystal Polymorphs
Thakuria, Ranjit, Arhangelskis, Mihails, Eddleston, Mark D, Chow, Ernest H. H, Sarmah, Kashyap Kumar, Aldous, Barry J, Krzyzaniak, Joseph F, Jones, William
Published in Organic process research & development (17.05.2019)
Published in Organic process research & development (17.05.2019)
Get full text
Journal Article
Effect of excipient properties, water activity, and water content on the disproportionation of a pharmaceutical salt
Patel, Mitulkumar A., Luthra, Suman, Shamblin, Sheri L., Arora, Kapildev K., Krzyzaniak, Joseph F., Taylor, Lynne S.
Published in International journal of pharmaceutics (30.07.2018)
Published in International journal of pharmaceutics (30.07.2018)
Get full text
Journal Article
Solid-State Characterization and Relative Formation Enthalpies To Evaluate Stability of Cocrystals of an Antidiabetic Drug
Duggirala, Naga Kiran, Frericks Schmidt, Heather L, Lei, Zhaohui, Zaworotko, Michael J, Krzyzaniak, Joseph F, Arora, Kapildev K
Published in Molecular pharmaceutics (07.05.2018)
Published in Molecular pharmaceutics (07.05.2018)
Get full text
Journal Article
Use of In Situ Atomic Force Microscopy to Follow Phase Changes at Crystal Surfaces in Real Time
Thakuria, Ranjit, Eddleston, Mark D., Chow, Ernest H. H., Lloyd, Gareth O., Aldous, Barry J., Krzyzaniak, Joseph F., Bond, Andrew D., Jones, William
Published in Angewandte Chemie International Edition (27.09.2013)
Published in Angewandte Chemie International Edition (27.09.2013)
Get full text
Journal Article
Excipient-Induced Lattice Disorder in Active Pharmaceutical Ingredient: Implications on Drug Product Continuous Manufacturing
Munjal, Bhushan, DeBoyace, Kevin, Cao, Fengjuan, Krzyzaniak, Joseph F., Arora, Kapildev K., Suryanarayanan, Raj
Published in Molecular pharmaceutics (07.10.2024)
Published in Molecular pharmaceutics (07.10.2024)
Get full text
Journal Article
Drug Phase Transformation and Water Redistribution during Continuous Tablet Manufacturing: A Case Study of Carbamazepine Dihydrate
Munjal, Bhushan, DeBoyace, Kevin, Cao, Fengjuan, Krzyzaniak, Joseph F., Arora, Kapildev K., Suryanarayanan, Raj
Published in Molecular pharmaceutics (03.07.2023)
Published in Molecular pharmaceutics (03.07.2023)
Get full text
Journal Article
Magnesium stearate surface coverage on tablets and drug crystals: Insights from SEM-EDS elemental mapping
Gunawardana, Chamara A., Kong, Angela, Blackwood, Daniel O., Travis Powell, C., Krzyzaniak, Joseph F., Thomas, Myles C., Calvin Sun, Changquan
Published in International journal of pharmaceutics (05.01.2023)
Published in International journal of pharmaceutics (05.01.2023)
Get full text
Journal Article
Powder properties and compaction parameters that influence punch sticking propensity of pharmaceuticals
Paul, Shubhajit, Taylor, Lisa J., Murphy, Brendan, Krzyzaniak, Joseph F., Dawson, Neil, Mullarney, Matthew P., Meenan, Paul, Sun, Changquan Calvin
Published in International journal of pharmaceutics (15.04.2017)
Published in International journal of pharmaceutics (15.04.2017)
Get full text
Journal Article
Crystalline mesophases: Structure, mobility, and pharmaceutical properties
Shalaev, Evgenyi, Wu, Ke, Shamblin, Sheri, Krzyzaniak, Joseph F., Descamps, Marc
Published in Advanced drug delivery reviews (01.05.2016)
Published in Advanced drug delivery reviews (01.05.2016)
Get full text
Journal Article
Toward a Molecular Understanding of the Impact of Crystal Size and Shape on Punch Sticking
Paul, Shubhajit, Taylor, Lisa J, Murphy, Brendan, Krzyzaniak, Joseph F, Dawson, Neil, Mullarney, Matthew P, Meenan, Paul, Sun, Changquan Calvin
Published in Molecular pharmaceutics (06.04.2020)
Published in Molecular pharmaceutics (06.04.2020)
Get full text
Journal Article
Understanding the role of magnesium stearate in lowering punch sticking propensity of drugs during compression
Gunawardana, Chamara A., Kong, Angela, Wanapun, Debbie, Blackwood, Daniel O., Travis Powell, C., Krzyzaniak, Joseph F., Thomas, Myles C., Kresevic, John E., Sun, Changquan Calvin
Published in International journal of pharmaceutics (10.06.2023)
Published in International journal of pharmaceutics (10.06.2023)
Get full text
Journal Article
Assessment of machine learning approaches for predicting the crystallization propensity of active pharmaceutical ingredients
Ghosh, Ayana, Louis, Lydie, Arora, Kapildev K., Hancock, Bruno C., Krzyzaniak, Joseph F., Meenan, Paul, Nakhmanson, Serge, Wood, Geoffrey P. F.
Published in CrystEngComm (2019)
Published in CrystEngComm (2019)
Get full text
Journal Article
Tale of Two Polymorphs: Investigating the Structural Differences and Dynamic Relationship between Nirmatrelvir Solid Forms (Paxlovid)
Sadeghi, Maryam Sadat, Guo, Rui, Bellucci, Michael A., Quino, Jaypee, Buckle, Erika L., Nisbet, Matthew L., Yang, Zhuocen, Greenwell, Chandler, Gorka, Danielle E., Pickard IV, Frank C., Wood, Geoffrey P. F., Sun, Guangxu, Wen, Shu-Hao, Krzyzaniak, Joseph F., Meenan, Paul A., Hancock, Bruno C., Yang, Xiaojing Helen
Published in Molecular pharmaceutics (05.08.2024)
Published in Molecular pharmaceutics (05.08.2024)
Get full text
Journal Article
Evaluation of the effect of new formulation, food, or a proton pump inhibitor on the relative bioavailability of the smoothened inhibitor glasdegib (PF-04449913) in healthy volunteers
Giri, Nagdeep, Lam, Lisa H., LaBadie, Robert R., Krzyzaniak, Joseph F., Jiang, Hong, Hee, Brian, Liang, Yali, Shaik, M. Naveed
Published in Cancer chemotherapy and pharmacology (01.12.2017)
Published in Cancer chemotherapy and pharmacology (01.12.2017)
Get full text
Journal Article
Impact of Solid-State Form on the Disproportionation of Miconazole Mesylate
Patel, Mitulkumar A, Luthra, Suman, Shamblin, Sheri L, Arora, Kapildev, Krzyzaniak, Joseph F, Taylor, Lynne S
Published in Molecular pharmaceutics (02.01.2018)
Published in Molecular pharmaceutics (02.01.2018)
Get full text
Journal Article