TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune cells for the treatment of cancer
Rosen, David B, Kvarnhammar, Anne Månsson, Laufer, Burkhardt, Knappe, Thomas, Karlsson, Jens Jakob, Hong, Enping, Lee, Yu-Chi, Thakar, Dhruv, Zúñiga, Luis Alejandro, Bang, Kathy, Sabharwal, Simran Singh, Uppal, Karan, Olling, Janne Damm, Kjaergaard, Kristian, Kurpiers, Thomas, Schnabel, Meike, Reich, Diana, Glock, Philipp, Zettler, Joachim, Krusch, Mathias, Bernhard, Ana, Heinig, Stefan, Konjik, Valentino, Wegge, Thomas, Hehn, Yvonne, Killian, Steffen, Viet, Laura, Runz, Josefine, Faltinger, Frank, Tabrizi, Mohammad, Abel, Kristin Laura, Breinholt, Vibeke Miller, Singel, Stina M, Sprogøe, Kennett, Punnonen, Juha
Published in Journal for immunotherapy of cancer (01.07.2022)
Published in Journal for immunotherapy of cancer (01.07.2022)
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Journal Article
Design and Preclinical Development of TransCon PTH, an Investigational Sustained‐Release PTH Replacement Therapy for Hypoparathyroidism
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Published in Journal of bone and mineral research (01.11.2019)
Published in Journal of bone and mineral research (01.11.2019)
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Journal Article
TransCon IL-2 β/γ, a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 analog, demonstrates improved pharmacokinetics and profound expansion of cytotoxic immune cells in non-human primates
Rosen, David, Månsson Kvarnhammar, Anne, Olling, Janne Damm, Laufer, Burkhardt, Knappe, Thomas, Karlsson, Jens Jakob, Kurpiers, Thomas, Zettler, Joachim, Runz, Josefine, Faltinger, Frank, Viet, Laura, Krusch, Mathias, Schnabel, Meike, Reich, Diana, Glock, Philipp, Singel, Stina Mui, Sprogøe, Kennett, Abel, Kristin Laura, Breinholt, Vibeke Miller, Punnonen, Juha
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Abstract 4507: TransConTM IL-2 β/γ: a novel long-acting prodrug of receptor-biased IL-2 designed for improved pharmocokinetics and optimal activation of T cells for the treatment of cancer
Rosen, David Brian, Laufer, Burkhardt, Knappe, Thomas, Schnabel, Meike, Begaliew, Diana, Zettler, Joachim, Krusch, Mathias, Bernhard, Ana, Heinig, Stefan, Konjik, Valentino, Wegge, Thomas, Breinholt, Vibeke, Tabrizi, Mohammad, Sprogoe, Kennett, Punnonen, Juha
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
PTH PTH PRODRUGS
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Year of Publication 31.01.2023
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Year of Publication 31.01.2023
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PTH PTH PRODRUGS
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Year of Publication 06.12.2021
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Year of Publication 30.10.2018
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Year of Publication 30.10.2018
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Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels
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Year of Publication 20.04.2023
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Biodegradable polyethylene glycol based water-insoluble hydrogels
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Year of Publication 24.01.2023
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Year of Publication 24.01.2023
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Year of Publication 30.09.2024
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Year of Publication 11.09.2024
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Controlled-Release PTH Compound
Holten-Andersen, Lars, Sprogøe, Kennett, Zettler, Joachim, Karpf, David Brian, Krusch, Mathias, Maitro, Guillaume, Wegge, Thomas
Year of Publication 25.07.2024
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Year of Publication 25.07.2024
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Year of Publication 18.04.2024
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Controlled-release PTH compound
Sprogøe, Kennett, Zettler, Joachim, Krusch, Mathias, Maitro, Guillaume, Wegge, Thomas, Cleemann, Felix
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Year of Publication 05.03.2024
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Controlled-release PTH compound
Sprogøe, Kennett, Zettler, Joachim, Krusch, Mathias, Maitro, Guillaume, Wegge, Thomas, Cleemann, Felix
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Year of Publication 06.02.2024
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PTH prodrugs
Sprogøe, Kennett, Zettler, Joachim, Krusch, Mathias, Maitro, Guillaume, Wegge, Thomas, Cleemann, Felix
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Year of Publication 18.01.2024
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Controlled-Release PTH Compound
Sprogøe, Kennett, Zettler, Joachim, Krusch, Mathias, Maitro, Guillaume, Wegge, Thomas, Cleemann, Felix
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Year of Publication 30.11.2023
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PTH prodrugs
Sprogøe, Kennett, Zettler, Joachim, Krusch, Mathias, Maitro, Guillaume, Wegge, Thomas, Cleemann, Felix
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Year of Publication 24.10.2023
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Dosage Regimen for a Controlled-Release PTH Compound
Sprogøe, Kennett, Zettler, Joachim, Krusch, Mathias, Maitro, Guillaume, Wegge, Thomas, Cleemann, Felix
Year of Publication 12.10.2023
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Year of Publication 12.10.2023
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