Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR
Zwarts, Irene, van Zutphen, Tim, Kruit, Janine K., Liu, Weilin, Oosterveer, Maaike H., Verkade, Henkjan J., Uhlenhaut, N. Henriette, Jonker, Johan W.
Published in Scientific reports (26.06.2019)
Published in Scientific reports (26.06.2019)
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Journal Article
Emerging roles of the intestine in control of cholesterol metabolism
Kruit, Janine-K, Groen, Albert K, van Berkel, Theo J, Kuipers, Folkert
Published in World journal of gastroenterology : WJG (28.10.2006)
Published in World journal of gastroenterology : WJG (28.10.2006)
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Journal Article
Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload
Vieira-Lara, Marcel A, Dommerholt, Marleen B, Zhang, Wenxuan, Blankestijn, Maaike, Wolters, Justina C, Abegaz, Fentaw, Gerding, Albert, van der Veen, Ydwine T, Thomas, Rachel, van Os, Ronald P, Reijngoud, Dirk-Jan, Jonker, Johan W, Kruit, Janine K, Bakker, Barbara M
Published in BMC biology (30.07.2021)
Published in BMC biology (30.07.2021)
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Journal Article
ABCA1 influences neuroinflammation and neuronal death
Karasinska, Joanna M, de Haan, Willeke, Franciosi, Sonia, Ruddle, Piers, Fan, Jianjia, Kruit, Janine K, Stukas, Sophie, Lütjohann, Dieter, Gutmann, David H, Wellington, Cheryl L, Hayden, Michael R
Published in Neurobiology of disease (01.06.2013)
Published in Neurobiology of disease (01.06.2013)
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Journal Article
Islet Cholesterol Accumulation Due to Loss of ABCA1 Leads to Impaired Exocytosis of Insulin Granules
KRUIT, Janine K, WIJESEKARA, Nadeeja, JOHNSON, James D, LIGHT, Peter E, MARSH, Brad J, MACDONALD, Patrick E, BRUCE VERCHERE, C, HAYDEN, Michael R, MANNING FOX, Jocelyn E, DAI, Xiao-Qing, BRUNHAM, Liam R, SEARLE, Gavin J, MORGAN, Garry P, COSTIN, Adam J, RENMEI TANG, BHATTACHARJEE, Alpana
Published in Diabetes (New York, N.Y.) (01.12.2011)
Published in Diabetes (New York, N.Y.) (01.12.2011)
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Journal Article
Macrophage ABCG1 Deletion Disrupts Lipid Homeostasis in Alveolar Macrophages and Moderately Influences Atherosclerotic Lesion Development in LDL Receptor-Deficient Mice
Out, Ruud, Hoekstra, Menno, Hildebrand, Reeni B, Kruit, Janine K, Meurs, Illiana, Li, Zhaosha, Kuipers, Folkert, Van Berkel, Theo J.C, Van Eck, Miranda
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2006)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2006)
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Journal Article
Specific Loss of Brain ABCA1 Increases Brain Cholesterol Uptake and Influences Neuronal Structure and Function
Karasinska, Joanna M, Rinninger, Franz, Lutjohann, Dieter, Ruddle, Piers, Franciosi, Sonia, Kruit, Janine K, Singaraja, Roshni R, Hirsch-Reinshagen, Veronica, Fan, Jianjia, Brunham, Liam R, Bissada, Nagat, Ramakrishnan, Rajasekhar, Wellington, Cheryl L, Parks, John S, Hayden, Michael R
Published in The Journal of neuroscience (18.03.2009)
Published in The Journal of neuroscience (18.03.2009)
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Journal Article
Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volume
Bernelot Moens, Sophie J, Mooij, Hans L, Hassing, H Carlijne, Kruit, Janine K, Witjes, Julia J, van de Sande, Michiel A J, Nederveen, Aart J, Xu, Ding, Dallinga-Thie, Geesje M, Esko, Jeffrey D, Stroes, Erik S G, Nieuwdorp, Max
Published in PloS one (26.12.2014)
Published in PloS one (26.12.2014)
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Journal Article
Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice
Kruit, Janine K, Plösch, Torsten, Havinga, Rick, Boverhof, Renze, Groot, Pieter H E, Groen, Albert K, Kuipers, Folkert
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2005)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2005)
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Journal Article
Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development
Guay, Claudiane, Kruit, Janine K., Rome, Sophie, Menoud, Véronique, Mulder, Niels L., Jurdzinski, Angelika, Mancarella, Francesca, Sebastiani, Guido, Donda, Alena, Gonzalez, Bryan J., Jandus, Camilla, Bouzakri, Karim, Pinget, Michel, Boitard, Christian, Romero, Pedro, Dotta, Francesco, Regazzi, Romano
Published in Cell metabolism (05.02.2019)
Published in Cell metabolism (05.02.2019)
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Journal Article
Reduction of Cholesterol Absorption by Dietary Plant Sterols and Stanols in Mice Is Independent of the Abcg5/8 Transporter
Plösch, Torsten, Kruit, Janine K, Bloks, Vincent W, Huijkman, Nicolette C.A, Havinga, Rick, Duchateau, Guus S.M.J.E, Lin, Yuguang, Kuipers, Folkert
Published in The Journal of nutrition (01.08.2006)
Published in The Journal of nutrition (01.08.2006)
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Journal Article
Plant Sterols Cause Macrothrombocytopenia in a Mouse Model of Sitosterolemia
Kruit, Janine K., Drayer, A. Lyndsay, Bloks, Vincent W., Blom, Nel, Olthof, Sandra G., Sauer, Pieter J.J., de Haan, Gerald, Kema, Ido P., Vellenga, Edo, Kuipers, Folkert
Published in The Journal of biological chemistry (07.03.2008)
Published in The Journal of biological chemistry (07.03.2008)
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Journal Article
The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient mice
Postmus, Andrea C., Kruit, Janine K., Eilers, Roos E., Havinga, Rick, Koster, Mirjam H., Johmura, Yoshikazu, Nakanishi, Makoto, van de Sluis, Bart, Jonker, Johan W.
Published in Toxicology and applied pharmacology (01.06.2023)
Published in Toxicology and applied pharmacology (01.06.2023)
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Journal Article
Autocrine FGF1 signaling promotes glucose uptake in adipocytes
Nies, Vera J M, Struik, Dicky, Liu, Sihao, Liu, Weilin, Kruit, Janine K, Downes, Michael, van Zutphen, Tim, Verkade, Henkjan J, Evans, Ronald M, Jonker, Johan W
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2022)
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Journal Article
AAV8-mediated gene transfer of microRNA-132 improves beta cell function in mice fed a high-fat diet
Mulder, Niels L, Havinga, Rick, Kluiver, Joost, Groen, Albert K, Kruit, Janine K
Published in Journal of endocrinology (01.02.2019)
Published in Journal of endocrinology (01.02.2019)
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Journal Article
β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
Verchere, C Bruce, Hayden, Michael R, Brunham, Liam R, Kruit, Janine K, Pape, Terry D, Timmins, Jenelle M, Reuwer, Anne Q, Vasanji, Zainisha, Marsh, Brad J, Rodrigues, Brian, Johnson, James D, Parks, John S
Published in Nature medicine (01.03.2007)
Published in Nature medicine (01.03.2007)
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Journal Article
Short‐term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue
Dommerholt, Marleen B., Blankestijn, Maaike, Vieira‐Lara, Marcel A., van Dijk, Theo H., Wolters, Henk, Koster, Mirjam H., Gerding, Albert, van Os, Ronald P., Bloks, Vincent W., Bakker, Barbara M., Kruit, Janine K., Jonker, Johan W.
Published in The FEBS journal (01.04.2021)
Published in The FEBS journal (01.04.2021)
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Journal Article
Cholesterol in islet dysfunction and type 2 diabetes
Brunham, Liam R, Kruit, Janine K, Verchere, C Bruce, Hayden, Michael R
Published in The Journal of clinical investigation (01.02.2008)
Published in The Journal of clinical investigation (01.02.2008)
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Journal Article
Loss of Both ABCA1 and ABCG1 Results in Increased Disturbances in Islet Sterol Homeostasis, Inflammation, and Impaired β-Cell Function
KRUIT, Janine K, WIJESEKARA, Nadeeja, BRUNHAM, Liam R, VERCHERE, C. Bruce, HAYDEN, Michael R, WESTWELL-ROPER, Clara, VANMIERLO, Tim, DE HAAN, Willeke, BHATTACHARJEE, Alpana, RENMEI TANG, WELLINGTON, Cheryl L, LÜTJOHANN, Dieter, JOHNSON, James D
Published in Diabetes (New York, N.Y.) (01.03.2012)
Published in Diabetes (New York, N.Y.) (01.03.2012)
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Journal Article