Recognizing the Molecular Multifunctionality and Interactome of TIMP-1
Grünwald, Barbara, Schoeps, Benjamin, Krüger, Achim
Published in Trends in cell biology (01.01.2019)
Published in Trends in cell biology (01.01.2019)
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Journal Article
Premetastatic niche formation in the liver: emerging mechanisms and mouse models
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Journal Article
Book Review
Functional disparities within the TIMP family in cancer: hints from molecular divergence
Eckfeld, Celina, Häußler, Daniel, Schoeps, Benjamin, Hermann, Chris D., Krüger, Achim
Published in Cancer and metastasis reviews (01.09.2019)
Published in Cancer and metastasis reviews (01.09.2019)
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Journal Article
TIMP1 Triggers Neutrophil Extracellular Trap Formation in Pancreatic Cancer
Schoeps, Benjamin, Eckfeld, Celina, Prokopchuk, Olga, Böttcher, Jan, Häußler, Daniel, Steiger, Katja, Demir, Ihsan Ekin, Knolle, Percy, Soehnlein, Oliver, Jenne, Dieter E., Hermann, Chris D., Krüger, Achim
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
Bayerl, Felix, Meiser, Philippa, Donakonda, Sainitin, Hirschberger, Anna, Lacher, Sebastian B., Pedde, Anna-Marie, Hermann, Chris D., Elewaut, Anais, Knolle, Moritz, Ramsauer, Lukas, Rudolph, Thomas J., Grassmann, Simon, Öllinger, Rupert, Kirchhammer, Nicole, Trefny, Marcel, Anton, Martina, Wohlleber, Dirk, Höchst, Bastian, Zaremba, Anne, Krüger, Achim, Rad, Roland, Obenauf, Anna C., Schadendorf, Dirk, Zippelius, Alfred, Buchholz, Veit R., Schraml, Barbara U., Böttcher, Jan P.
Published in Immunity (Cambridge, Mass.) (13.06.2023)
Published in Immunity (Cambridge, Mass.) (13.06.2023)
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Journal Article
Molecular targets and pathways involved in liver metastasis of colorectal cancer
Weidle, Ulrich H., Birzele, Fabian, Krüger, Achim
Published in Clinical & experimental metastasis (01.08.2015)
Published in Clinical & experimental metastasis (01.08.2015)
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Journal Article
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis
Bolik, Julia, Krause, Freia, Stevanovic, Marija, Gandraß, Monja, Thomsen, Ilka, Schacht, Sarah-Sophie, Rieser, Eva, Müller, Miryam, Schumacher, Neele, Fritsch, Jürgen, Wichert, Rielana, Galun, Eithan, Bergmann, Juri, Röder, Christian, Schafmayer, Clemens, Egberts, Jan-Hendrik, Becker-Pauly, Christoph, Saftig, Paul, Lucius, Ralph, Schneider-Brachert, Wulf, Barikbin, Roja, Adam, Dieter, Voss, Matthias, Hitzl, Wolfgang, Krüger, Achim, Strilic, Boris, Sagi, Irit, Walczak, Henning, Rose-John, Stefan, Schmidt-Arras, Dirk
Published in The Journal of experimental medicine (03.01.2022)
Published in The Journal of experimental medicine (03.01.2022)
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Journal Article
Identification of invariant chain CD74 as a functional receptor of tissue inhibitor of metalloproteinases-1 (TIMP-1)
Schoeps, Benjamin, Eckfeld, Celina, Flüter, Laura, Keppler, Selina, Mishra, Ritu, Knolle, Percy, Bayerl, Felix, Böttcher, Jan, Hermann, Chris D., Häußler, Daniel, Krüger, Achim
Published in The Journal of biological chemistry (01.09.2021)
Published in The Journal of biological chemistry (01.09.2021)
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Journal Article
Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the α-Ketoamide Electrophile as an Auspicious Reversible Lead Motif
Stein, Martin L., Cui, Haissi, Beck, Philipp, Dubiella, Christian, Voss, Constantin, Krüger, Achim, Schmidt, Boris, Groll, Michael
Published in Angewandte Chemie (International ed.) (03.02.2014)
Published in Angewandte Chemie (International ed.) (03.02.2014)
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Journal Article
Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice
Seubert, Bastian, Grünwald, Barbara, Kobuch, Julia, Cui, Haissi, Schelter, Florian, Schaten, Susanne, Siveke, Jens T., Lim, Ngee H., Nagase, Hideaki, Simonavicius, Nicole, Heikenwalder, Mathias, Reinheckel, Thomas, Sleeman, Jonathan P., Janssen, Klaus‐Peter, Knolle, Percy A., Krüger, Achim
Published in Hepatology (Baltimore, Md.) (01.01.2015)
Published in Hepatology (Baltimore, Md.) (01.01.2015)
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Journal Article
TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer
Hermann, Chris D, Schoeps, Benjamin, Eckfeld, Celina, Munkhbaatar, Enkhtsetseg, Kniep, Lukas, Prokopchuk, Olga, Wirges, Nils, Steiger, Katja, Häußler, Daniel, Knolle, Percy, Poulton, Emily, Khokha, Rama, Grünwald, Barbara T, Demir, Ihsan Ekin, Krüger, Achim
Published in The Journal of experimental medicine (01.11.2021)
Published in The Journal of experimental medicine (01.11.2021)
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Journal Article
Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver
Grünwald, Barbara, Harant, Veronika, Schaten, Susanne, Frühschütz, Monika, Spallek, Ria, Höchst, Bastian, Stutzer, Katharina, Berchtold, Sonja, Erkan, Mert, Prokopchuk, Olga, Martignoni, Marc, Esposito, Irene, Heikenwalder, Mathias, Gupta, Aayush, Siveke, Jens, Saftig, Paul, Knolle, Percy, Wohlleber, Dirk, Krüger, Achim
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2016)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2016)
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Journal Article
Matrix metalloproteinase-9 (MMP-9) as an activator of nanosystems for targeted drug delivery in pancreatic cancer
Grünwald, Barbara, Vandooren, Jennifer, Locatelli, Erica, Fiten, Pierre, Opdenakker, Ghislain, Proost, Paul, Krüger, Achim, Lellouche, Jean Paul, Israel, Liron Limor, Shenkman, Louis, Comes Franchini, Mauro
Published in Journal of controlled release (10.10.2016)
Published in Journal of controlled release (10.10.2016)
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Journal Article
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes
Eckfeld, Celina, Schoeps, Benjamin, Häußler, Daniel, Frädrich, Julian, Bayerl, Felix, Böttcher, Jan Philipp, Knolle, Percy, Heisz, Simone, Prokopchuk, Olga, Hauner, Hans, Munkhbaatar, Enkhtsetseg, Demir, Ihsan Ekin, Hermann, Chris D, Krüger, Achim
Published in The Journal of cell biology (06.02.2023)
Published in The Journal of cell biology (06.02.2023)
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Journal Article
Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow
Grünwald, Barbara, Vandooren, Jennifer, Gerg, Michael, Ahomaa, Kaarin, Hunger, Annique, Berchtold, Sonja, Akbareian, Sophia, Schaten, Susanne, Knolle, Percy, Edwards, Dylan R, Opdenakker, Ghislain, Krüger, Achim
Published in Molecular cancer research (01.11.2016)
Published in Molecular cancer research (01.11.2016)
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Journal Article
Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells
Demir, Ihsan Ekin, Kujundzic, Kristina, Pfitzinger, Paulo L., Saricaoglu, Ömer Cemil, Teller, Steffen, Kehl, Timo, Reyes, Carmen Mota, Ertl, Linda S., Miao, Zhenhua, Schall, Thomas J., Tieftrunk, Elke, Haller, Bernhard, Diakopoulos, Kalliope Nina, Kurkowski, Magdalena U., Lesina, Marina, Krüger, Achim, Algül, Hana, Friess, Helmut, Ceyhan, Güralp O.
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2017)
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Journal Article
Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site
Dubiella, Christian, Cui, Haissi, Gersch, Malte, Brouwer, Arwin J., Sieber, Stephan A., Krüger, Achim, Liskamp, Rob M. J., Groll, Michael
Published in Angewandte Chemie (International ed.) (27.10.2014)
Published in Angewandte Chemie (International ed.) (27.10.2014)
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Journal Article
Tetraspanin CD63 acts as a pro‐metastatic factor via β‐catenin stabilization
Seubert, Bastian, Cui, Haissi, Simonavicius, Nicole, Honert, Katja, Schäfer, Sandra, Reuning, Ute, Heikenwalder, Mathias, Mari, Bernard, Krüger, Achim
Published in International journal of cancer (15.05.2015)
Published in International journal of cancer (15.05.2015)
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