Sex differences in metabolism and cardiometabolic disorders
Chella Krishnan, Karthickeyan, Mehrabian, Margarete, Lusis, Aldons J
Published in Current opinion in lipidology (01.10.2018)
Published in Current opinion in lipidology (01.10.2018)
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Journal Article
Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits
Norheim, Frode, Hasin-Brumshtein, Yehudit, Vergnes, Laurent, Chella Krishnan, Karthickeyan, Pan, Calvin, Seldin, Marcus M., Hui, Simon T., Mehrabian, Margarete, Zhou, Zhiqiang, Gupta, Sonul, Parks, Brian W., Walch, Axel, Reue, Karen, Hofmann, Susanna M., Arnold, Arthur P., Lusis, Aldons J.
Published in Cell metabolism (02.04.2019)
Published in Cell metabolism (02.04.2019)
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Journal Article
Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease
Chella Krishnan, Karthickeyan, Kurt, Zeyneb, Barrere-Cain, Rio, Sabir, Simon, Das, Aditi, Floyd, Raquel, Vergnes, Laurent, Zhao, Yuqi, Che, Nam, Charugundla, Sarada, Qi, Hannah, Zhou, Zhiqiang, Meng, Yonghong, Pan, Calvin, Seldin, Marcus M., Norheim, Frode, Hui, Simon, Reue, Karen, Lusis, Aldons J., Yang, Xia
Published in Cell systems (24.01.2018)
Published in Cell systems (24.01.2018)
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Journal Article
Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR [S]
Norheim, Frode, Bjellaas, Thomas, Hui, Simon T., Chella Krishnan, Karthickeyan, Lee, Jakleen, Gupta, Sonul, Pan, Calvin, Hasin-Brumshtein, Yehudit, Parks, Brian W., Li, Daniel Y., Bui, Hai H., Mosier, Marian, Wu, Yuping, Huertas-Vazquez, Adriana, Hazen, Stanley L., Gundersen, Thomas E., Mehrabian, Margarete, Tang, W.H.Wilson, Hevener, Andrea L., Drevon, Christian A., Lusis, Aldons J.
Published in Journal of lipid research (2018)
Published in Journal of lipid research (2018)
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Journal Article
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis
Norheim, Frode, Chella Krishnan, Karthickeyan, Bjellaas, Thomas, Vergnes, Laurent, Pan, Calvin, Parks, Brian W, Meng, Yonghong, Lang, Jennifer, Ward, James A, Reue, Karen, Mehrabian, Margarete, Gundersen, Thomas E, Péterfy, Miklós, Dalen, Knut T, Drevon, Christian A, Hui, Simon T, Lusis, Aldons J, Seldin, Marcus M
Published in Molecular systems biology (01.01.2021)
Published in Molecular systems biology (01.01.2021)
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Journal Article
Host Genetic Variations and Sex Differences Potentiate Predisposition, Severity, and Outcomes of Group A Streptococcus-Mediated Necrotizing Soft Tissue Infections
Chella Krishnan, Karthickeyan, Mukundan, Santhosh, Alagarsamy, Jeyashree, Laturnus, Donna, Kotb, Malak
Published in Infection and immunity (01.02.2016)
Published in Infection and immunity (01.02.2016)
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Journal Article
Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse
Chella Krishnan, Karthickeyan, Mukundan, Santhosh, Alagarsamy, Jeyashree, Hur, Junguk, Nookala, Suba, Siemens, Nikolai, Svensson, Mattias, Hyldegaard, Ole, Norrby-Teglund, Anna, Kotb, Malak
Published in PLoS pathogens (01.07.2016)
Published in PLoS pathogens (01.07.2016)
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Journal Article
Sex-specific metabolic functions of adipose Lipocalin-2
Chella Krishnan, Karthickeyan, Sabir, Simon, Shum, Michaël, Meng, Yonghong, Acín-Pérez, Rebeca, Lang, Jennifer M., Floyd, Raquel R., Vergnes, Laurent, Seldin, Marcus M., Fuqua, Brie K., Jayasekera, Dulshan W., Nand, Sereena K., Anum, Diana C., Pan, Calvin, Stiles, Linsey, Péterfy, Miklós, Reue, Karen, Liesa, Marc, Lusis, Aldons J.
Published in Molecular metabolism (Germany) (01.12.2019)
Published in Molecular metabolism (Germany) (01.12.2019)
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Journal Article
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2
Chella Krishnan, Karthickeyan, Vergnes, Laurent, Acín-Pérez, Rebeca, Stiles, Linsey, Shum, Michael, Ma, Lijiang, Mouisel, Etienne, Pan, Calvin, Moore, Timothy M, Péterfy, Miklós, Romanoski, Casey E, Reue, Karen, Björkegren, Johan L M, Laakso, Markku, Liesa, Marc, Lusis, Aldons J
Published in Nature metabolism (01.11.2021)
Published in Nature metabolism (01.11.2021)
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Hepatokine ITIH3 protects against hepatic steatosis by downregulating mitochondrial bioenergetics and de novo lipogenesis
Talari, Noble Kumar, Mattam, Ushodaya, Kaminska, Dorota, Sotomayor-Rodriguez, Irene, Rahman, Afra P., Péterfy, Miklós, Pajukanta, Päivi, Pihlajamäki, Jussi, Chella Krishnan, Karthickeyan
Published in iScience (17.05.2024)
Published in iScience (17.05.2024)
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Journal Article
Sex differences in heart mitochondria regulate diastolic dysfunction
Cao, Yang, Vergnes, Laurent, Wang, Yu-Chen, Pan, Calvin, Chella Krishnan, Karthickeyan, Moore, Timothy M, Rosa-Garrido, Manuel, Kimball, Todd H, Zhou, Zhiqiang, Charugundla, Sarada, Rau, Christoph D, Seldin, Marcus M, Wang, Jessica, Wang, Yibin, Vondriska, Thomas M, Reue, Karen, Lusis, Aldons J
Published in Nature communications (04.07.2022)
Published in Nature communications (04.07.2022)
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Journal Article
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity
Shum, Michael, Shintre, Chitra A, Althoff, Thorsten, Gutierrez, Vincent, Segawa, Mayuko, Saxberg, Alexandra D, Martinez, Melissa, Adamson, Roslin, Young, Margaret R, Faust, Belinda, Gharakhanian, Raffi, Su, Shi, Chella Krishnan, Karthickeyan, Mahdaviani, Kiana, Veliova, Michaela, Wolf, Dane M, Ngo, Jennifer, Nocito, Laura, Stiles, Linsey, Abramson, Jeff, Lusis, Aldons J, Hevener, Andrea L, Zoghbi, Maria E, Carpenter, Elisabeth P, Liesa, Marc
Published in Science translational medicine (19.05.2021)
Published in Science translational medicine (19.05.2021)
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Mammary duct luminal epithelium controls adipocyte thermogenic programme
Patel, Sanil, Sparman, Njeri Z R, Arneson, Douglas, Alvarsson, Alexandra, Santos, Luís C, Duesman, Samuel J, Centonze, Alessia, Hathaway, Ephraim, Ahn, In Sook, Diamante, Graciel, Cely, Ingrid, Cho, Chung Hwan, Talari, Noble Kumar, Rajbhandari, Abha K, Goedeke, Leigh, Wang, Peng, Butte, Atul J, Blanpain, Cédric, Chella Krishnan, Karthickeyan, Lusis, Aldons J, Stanley, Sarah A, Yang, Xia, Rajbhandari, Prashant
Published in Nature (London) (03.08.2023)
Published in Nature (London) (03.08.2023)
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Journal Article
The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in Mice
Hui, Simon T., Kurt, Zeyneb, Tuominen, Iina, Norheim, Frode, C.Davis, Richard, Pan, Calvin, Dirks, Darwin L., Magyar, Clara E., French, Samuel W., Chella Krishnan, Karthickeyan, Sabir, Simon, Campos‐Pérez, Francisco, Méndez‐Sánchez, Nahum, Macías‐Kauffer, Luis, León‐Mimila, Paola, Canizales‐Quinteros, Samuel, Yang, Xia, Beaven, Simon W., Huertas‐Vazquez, Adriana, Lusis, Aldons J.
Published in Hepatology (Baltimore, Md.) (01.12.2018)
Published in Hepatology (Baltimore, Md.) (01.12.2018)
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Journal Article
A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism
Seldin, Marcus M., Koplev, Simon, Rajbhandari, Prashant, Vergnes, Laurent, Rosenberg, Gregory M., Meng, Yonghong, Pan, Calvin, Phuong, Thuy M.N., Gharakhanian, Raffi, Che, Nam, Mäkinen, Selina, Shih, Diana M., Civelek, Mete, Parks, Brian W., Kim, Eric D., Norheim, Frode, Chella Krishnan, Karthickeyan, Hasin-Brumshtein, Yehudit, Mehrabian, Margarete, Laakso, Markku, Drevon, Christian A., Koistinen, Heikki A., Tontonoz, Peter, Reue, Karen, Cantor, Rita M., Björkegren, Johan L.M., Lusis, Aldons J.
Published in Cell metabolism (01.05.2018)
Published in Cell metabolism (01.05.2018)
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Journal Article
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner
Chella Krishnan, Karthickeyan, Floyd, Raquel R., Sabir, Simon, Jayasekera, Dulshan W., Leon-Mimila, Paola V., Jones, Anthony E., Cortez, Angel A., Shravah, Varun, Péterfy, Miklós, Stiles, Linsey, Canizales-Quinteros, Samuel, Divakaruni, Ajit S., Huertas-Vazquez, Adriana, Lusis, Aldons J.
Published in Cellular and molecular gastroenterology and hepatology (01.01.2021)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2021)
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Journal Article
Recruitment and remodeling of peridroplet mitochondria in human adipose tissue
Acín-Perez, Rebeca, Petcherski, Anton, Veliova, Michaela, Benador, Ilan Y., Assali, Essam A., Colleluori, Georgia, Cinti, Saverio, Brownstein, Alexandra J., Baghdasarian, Siyouneh, Livhits, Masha J., Yeh, Michael W., Krishnan, Karthickeyan Chella, Vergnes, Laurent, Winn, Nathan C., Padilla, Jaume, Liesa, Marc, Sacks, Harold S., Shirihai, Orian S.
Published in Redox biology (01.10.2021)
Published in Redox biology (01.10.2021)
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Journal Article
Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy
Chella Krishnan, Karthickeyan, El Hachem, Elie-Julien, Keller, Mark P, Patel, Sanjeet G, Carroll, Luke, Vegas, Alexis Diaz, Gerdes Gyuricza, Isabela, Light, Christine, Cao, Yang, Pan, Calvin, Kaczor-Urbanowicz, Karolina Elżbieta, Shravah, Varun, Anum, Diana, Pellegrini, Matteo, Lee, Chi Fung, Seldin, Marcus M, Rosenthal, Nadia A, Churchill, Gary A, Attie, Alan D, Parker, Benjamin, James, David E, Lusis, Aldons J
Published in eLife (05.06.2023)
Published in eLife (05.06.2023)
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