Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors
Azeredo, Luís Felipe S.P., Coutinho, Julia P., Jabor, Valquiria A.P., Feliciano, Patricia R., Nonato, Maria Cristina, Kaiser, Carlos R., Menezes, Carla Maria S., Hammes, Amanda S.O., Caffarena, Ernesto Raul, Hoelz, Lucas V.B., de Souza, Nicolli B., Pereira, Glaécia A.N., Cerávolo, Isabela P., Krettli, Antoniana U., Boechat, Nubia
Published in European journal of medicinal chemistry (27.01.2017)
Published in European journal of medicinal chemistry (27.01.2017)
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New hybrid trifluoromethylquinolines as antiplasmodium agents
da Silva, Renata M.R.J., Gandi, Marilia O., Mendonça, Jorge S., Carvalho, Alcione S., Coutinho, Julia Penna, Aguiar, Anna C.C., Krettli, Antoniana U., Boechat, Nubia
Published in Bioorganic & medicinal chemistry (15.03.2019)
Published in Bioorganic & medicinal chemistry (15.03.2019)
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Studies on Activities and Chemical Characterization of Medicinal Plants in Search for New Antimalarials: A Ten Year Review on Ethnopharmacology
Ceravolo, Isabela P., Aguiar, Anna C., Adebayo, Joseph O., Krettli, Antoniana U.
Published in Frontiers in pharmacology (22.09.2021)
Published in Frontiers in pharmacology (22.09.2021)
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Chloroquine analogs as antimalarial candidates with potent in vitro and in vivo activity
Aguiar, Anna C.C., Murce, Erika, Cortopassi, Wilian A., Pimentel, Andre S., Almeida, Maria M.F.S., Barros, Daniele C.S., Guedes, Jéssica S., Meneghetti, Mario R., Krettli, Antoniana U.
Published in International journal for parasitology -- drugs and drug resistance (01.12.2018)
Published in International journal for parasitology -- drugs and drug resistance (01.12.2018)
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Antimalarial and antioxidant activities of novel artesunate-ellagic acid hybrid compound in vitro and in vivo
Ishola, Ahmed A, Adebayo, Joseph O, Ceravolo, Isabela P, Tijjani, Habibu, Bento, Edson S, Goulart, Henrique F, Crispim, Alessandre C, Balogun, Elizabeth A, Santana, Antonio E G, Krettli, Antoniana U
Published in Frontiers in pharmacology (18.06.2024)
Published in Frontiers in pharmacology (18.06.2024)
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Synthesis and antimalarial activity of semicarbazone and thiosemicarbazone derivatives
de Oliveira, Renata B., de Souza-Fagundes, Elaine M., Soares, Rodrigo P.P., Andrade, Anderson A., Krettli, Antoniana U., Zani, Carlos L.
Published in European journal of medicinal chemistry (01.09.2008)
Published in European journal of medicinal chemistry (01.09.2008)
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Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high antiplasmodial activity and low cytotoxicity
Ceravolo, Isabela P, Zani, Carlos L, Figueiredo, Flávio J B, Kohlhoff, Markus, Santana, Antônio E G, Krettli, Antoniana U
Published in Malaria journal (26.11.2018)
Published in Malaria journal (26.11.2018)
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Journal Article
New Compounds Hybrids 1H-1,2,3-Triazole-Quinoline Against Plasmodium falciparum
Boechat, Núbia, Ferreira, Maria de Lourdes G., Pinheiro, Luiz C. S., Jesus, Antônio M. L., Leite, Milene M. M., Júnior, Carlos C. S., Aguiar, Anna C. C., de Andrade, Isabel M., Krettli, Antoniana U.
Published in Chemical biology & drug design (01.09.2014)
Published in Chemical biology & drug design (01.09.2014)
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In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon
Lima, Renata B S, Rocha e Silva, Luiz F, Melo, Marcia R S, Costa, Jaqueline S, Picanço, Neila S, Lima, Emerson S, Vasconcellos, Marne C, Boleti, Ana Paula A, Santos, Jakeline M P, Amorim, Rodrigo C N, Chaves, Francisco C M, Coutinho, Julia P, Tadei, Wanderli P, Krettli, Antoniana U, Pohlit, Adrian M
Published in Malaria journal (18.12.2015)
Published in Malaria journal (18.12.2015)
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Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum
Chierrito, Talita P C, Aguiar, Anna C C, de Andrade, Isabel M, Ceravolo, Isabela P, Gonçalves, Regina A C, de Oliveira, Arildo J B, Krettli, Antoniana U
Published in Malaria journal (14.04.2014)
Published in Malaria journal (14.04.2014)
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Novel 2,5-Diketopiperazines with In Vitro Activities against Protozoan Parasites of Tropical Diseases
Ceravolo, Isabela P, Leoni, Letícia F, Krettli, Antoniana U, Murta, Silvane M F, Resende, Daniela de M, Cruz, Mariza G F de M L, Varejão, Jodieh O S, Mendes, Lorena L, Varejão, Eduardo V V, Kohlhoff, Markus
Published in Pharmaceuticals (Basel, Switzerland) (01.02.2024)
Published in Pharmaceuticals (Basel, Switzerland) (01.02.2024)
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Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues
Cortopassi, Wilian A., Gunderson, Emma, Annunciato, Yasmin, Silva, Antony.E.S., dos Santos Ferreira, Amália, Garcia Teles, Carolina Bioni, Pimentel, Andre S., Ramamoorthi, Roopa, Gazarini, Marcos L, Meneghetti, Mario R., Guido, Rafael.V.C., Pereira, Dhelio B., Jacobson, Matthew P., Krettli, Antoniana U., Caroline C Aguiar, Anna
Published in International journal for parasitology -- drugs and drug resistance (01.12.2022)
Published in International journal for parasitology -- drugs and drug resistance (01.12.2022)
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Theoretical and experimental studies of new modified isoflavonoids as potential inhibitors of topoisomerase I from Plasmodium falciparum
Cortopassi, Wilian A, Penna-Coutinho, Julia, Aguiar, Anna C C, Pimentel, André S, Buarque, Camilla D, Costa, Paulo R R, Alves, Bruna R M, França, Tanos C C, Krettli, Antoniana U
Published in PloS one (20.03.2014)
Published in PloS one (20.03.2014)
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Journal Article
Antiplasmodial Activity of Aryltetralone Lignans from Holostylis reniformis
DE ANDRADE-NETO, Valter F, DA SILVA, Tito, XAVIER LOPES, Lucia M, DO ROSARIO, Virgilio E, DE PILLA VAROTTI, Fernando, KRETTLI, Antoniana U
Published in Antimicrobial Agents and Chemotherapy (01.07.2007)
Published in Antimicrobial Agents and Chemotherapy (01.07.2007)
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Synthesis, antimalarial evaluation and molecular modeling studies of hydroxyethylpiperazines, potential aspartyl protease inhibitors, Part 2
Cunico, Wilson, Gomes, Claudia R.B., Facchinetti, Victor, Moreth, Marcele, Penido, Carmen, Henriques, Maria G.M.O., Varotti, Fernando P., Krettli, Luisa G., Krettli, Antoniana U., da Silva, Franklin S., Caffarena, Ernesto R., de Magalhães, Camila S.
Published in European journal of medicinal chemistry (01.09.2009)
Published in European journal of medicinal chemistry (01.09.2009)
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Journal Article
Cysteine-stabilised peptide extract of Morinda lucida (Benth) leaf exhibits antimalarial activity and augments antioxidant defense system in P. berghei-infected mice
Adebayo, Joseph O., Adewole, Kayode E., Krettli, Antoniana U.
Published in Journal of ethnopharmacology (31.07.2017)
Published in Journal of ethnopharmacology (31.07.2017)
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Journal Article
The Search for New Antimalarial Drugs from Plants Used to Treat Fever and Malaria or Plants Ramdomly Selected: a Review
Krettli, Antoniana U, Andrade-Neto, Valter F, Brandão, Maria das Graças L, Ferrari, Wanêssa MS
Published in Memórias do Instituto Oswaldo Cruz (01.11.2001)
Published in Memórias do Instituto Oswaldo Cruz (01.11.2001)
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Antimalarial and anti-inflammatory activities of new chloroquine and primaquine hybrids: Targeting the blockade of malaria parasite transmission
Boechat, Nubia, Carvalho, Rita C.C., Ferreira, Maria de Lourdes G., Coutinho, Julia Penna, Sa, Paula M., Seito, Leonardo N., Rosas, Elaine C., Krettli, Antoniana U., Bastos, Monica M., Pinheiro, Luiz C.S.
Published in Bioorganic & medicinal chemistry (15.12.2020)
Published in Bioorganic & medicinal chemistry (15.12.2020)
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