Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology
Hirsch, Alec J., Roberts, Victoria H. J., Grigsby, Peta L., Haese, Nicole, Schabel, Matthias C., Wang, Xiaojie, Lo, Jamie O., Liu, Zheng, Kroenke, Christopher D., Smith, Jessica L., Kelleher, Meredith, Broeckel, Rebecca, Kreklywich, Craig N., Parkins, Christopher J., Denton, Michael, Smith, Patricia, DeFilippis, Victor, Messer, William, Nelson, Jay A., Hennebold, Jon D., Grafe, Marjorie, Colgin, Lois, Lewis, Anne, Ducore, Rebecca, Swanson, Tonya, Legasse, Alfred W., Axthelm, Michael K., MacAllister, Rhonda, Moses, Ashlee V., Morgan, Terry K., Frias, Antonio E., Streblow, Daniel N.
Published in Nature communications (17.01.2018)
Published in Nature communications (17.01.2018)
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Development of a next-generation chikungunya virus vaccine based on the HydroVax platform
Slifka, Dawn K, Raué, Hans-Peter, Weber, Whitney C, Andoh, Takeshi F, Kreklywich, Craig N, DeFilippis, Victor R, Streblow, Daniel N, Slifka, Mark K, Amanna, Ian J
Published in PLoS pathogens (05.07.2022)
Published in PLoS pathogens (05.07.2022)
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A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection
Umashankar, Mahadevaiah, Petrucelli, Alex, Cicchini, Louis, Caposio, Patrizia, Kreklywich, Craig N, Rak, Michael, Bughio, Farah, Goldman, Devorah C, Hamlin, Kimberly L, Nelson, Jay A, Fleming, William H, Streblow, Daniel N, Goodrum, Felicia
Published in PLoS pathogens (01.12.2011)
Published in PLoS pathogens (01.12.2011)
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Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity
Messaoudi, Ilhem, Vomaske, Jennifer, Totonchy, Thomas, Kreklywich, Craig N, Haberthur, Kristen, Springgay, Laura, Brien, James D, Diamond, Michael S, Defilippis, Victor R, Streblow, Daniel N
Published in PLoS neglected tropical diseases (2013)
Published in PLoS neglected tropical diseases (2013)
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Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation
Medica, Samuel, Crawford, Lindsey B, Denton, Michael, Min, Chan-Ki, Jones, Taylor A, Alexander, Timothy, Parkins, Christopher J, Diggins, Nicole L, Streblow, Gabriel J, Mayo, Adam T, Kreklywich, Craig N, Smith, Patricia, Jeng, Sophia, McWeeney, Shannon, Hancock, Meaghan H, Yurochko, Andrew, Cohen, Michael S, Caposio, Patrizia, Streblow, Daniel N
Published in PLoS pathogens (02.10.2023)
Published in PLoS pathogens (02.10.2023)
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Src Family Kinase Inhibitors Block Translation of Alphavirus Subgenomic mRNAs
Broeckel, Rebecca, Sarkar, Sanjay, May, Nicholas A, Totonchy, Jennifer, Kreklywich, Craig N, Smith, Patricia, Graves, Lee, DeFilippis, Victor R, Heise, Mark T, Morrison, Thomas E, Moorman, Nathaniel, Streblow, Daniel N
Published in Antimicrobial agents and chemotherapy (01.04.2019)
Published in Antimicrobial agents and chemotherapy (01.04.2019)
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Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques
Broeckel, Rebecca, Fox, Julie M, Haese, Nicole, Kreklywich, Craig N, Sukulpovi-Petty, Soila, Legasse, Alfred, Smith, Patricia P, Denton, Michael, Corvey, Carsten, Krishnan, Shiv, Colgin, Lois M A, Ducore, Rebecca M, Lewis, Anne D, Axthelm, Michael K, Mandron, Marie, Cortez, Pierre, Rothblatt, Jonathan, Rao, Ercole, Focken, Ingo, Carter, Kara, Sapparapau, Gopal, Crowe, Jr, James E, Diamond, Michael S, Streblow, Daniel N
Published in PLoS neglected tropical diseases (19.06.2017)
Published in PLoS neglected tropical diseases (19.06.2017)
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IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin
Botto, Sara, Streblow, Daniel N., DeFilippis, Victor, White, Laura, Kreklywich, Craig N., Smith, Patricia P., Caposio, Patrizia
Published in Blood (06.01.2011)
Published in Blood (06.01.2011)
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Mayaro virus pathogenesis and immunity in rhesus macaques
Weber, Whitney C, Labriola, Caralyn S, Kreklywich, Craig N, Ray, Karina, Haese, Nicole N, Andoh, Takeshi F, Denton, Michael, Medica, Samuel, Streblow, Magdalene M, Smith, Patricia P, Mizuno, Nobuyo, Frias, Nina, Fisher, Miranda B, Barber-Axthelm, Aaron M, Chun, Kimberly, Uttke, Samantha, Whitcomb, Danika, DeFilippis, Victor, Rakshe, Shauna, Fei, Suzanne S, Axthelm, Michael K, Smedley, Jeremy V, Streblow, Daniel N
Published in PLoS neglected tropical diseases (20.11.2023)
Published in PLoS neglected tropical diseases (20.11.2023)
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Blocking the IL‐1 receptor reduces cardiac transplant ischemia and reperfusion injury and mitigates CMV‐accelerated chronic rejection
Jones, Iris K. A., Orloff, Susan, Burg, Jennifer M., Haese, Nicole N., Andoh, Takeshi F., Chambers, Ashley, Fei, Suzanne S., Gao, Lina, Kreklywich, Craig N., Streblow, Zachary J., Enesthvedt, Kristian, Wanderer, Alan, Baker, James, Streblow, Daniel N.
Published in American journal of transplantation (01.01.2021)
Published in American journal of transplantation (01.01.2021)
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Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34 + Hematopoietic Progenitor Cells and Humanized NSG Mice
Crawford, Lindsey B, Caposio, Patrizia, Kreklywich, Craig, Pham, Andrew H, Hancock, Meaghan H, Jones, Taylor A, Smith, Patricia P, Yurochko, Andrew D, Nelson, Jay A, Streblow, Daniel N
Published in mBio (20.08.2019)
Published in mBio (20.08.2019)
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Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease
Broeckel, Rebecca M, Haese, Nicole, Ando, Takeshi, Dmitriev, Igor, Kreklywich, Craig N, Powers, John, Denton, Michael, Smith, Patricia, Morrison, Thomas E, Heise, Mark, DeFilippis, Victor, Messaoudi, Ilhem, Curiel, David T, Streblow, Daniel N
Published in Frontiers in immunology (31.10.2019)
Published in Frontiers in immunology (31.10.2019)
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Journal Article
Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice
Crawford, Lindsey B., Tempel, Rebecca, Streblow, Daniel N., Kreklywich, Craig, Smith, Patricia, Picker, Louis J., Nelson, Jay A., Caposio, Patrizia
Published in Scientific reports (20.04.2017)
Published in Scientific reports (20.04.2017)
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Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity
Marshall, Emily E, Malouli, Daniel, Hansen, Scott G, Gilbride, Roxanne M, Hughes, Colette M, Ventura, Abigail B, Ainslie, Emily, Selseth, Andrea N, Ford, Julia C, Burke, David, Kreklywich, Craig N, Womack, Jennie, Legasse, Alfred W, Axthelm, Michael K, Kahl, Christoph, Streblow, Daniel, Edlefsen, Paul T, Picker, Louis J, Früh, Klaus
Published in Science translational medicine (17.07.2019)
Published in Science translational medicine (17.07.2019)
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Journal Article
Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model
Smith, M Shane, Goldman, Devorah C, Bailey, Alexis S, Pfaffle, Dana L, Kreklywich, Craig N, Spencer, Doran B, Othieno, Florence A, Streblow, Daniel N, Garcia, J Victor, Fleming, William H, Nelson, Jay A
Published in Cell host & microbe (16.09.2010)
Published in Cell host & microbe (16.09.2010)
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Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors
Ahmed, S. Kaleem, Haese, Nicole N, Cowan, Jaden T, Pathak, Vibha, Moukha-Chafiq, Omar, Smith, Valerie J, Rodzinak, Kevin J, Ahmad, Fahim, Zhang, Sixue, Bonin, Kiley M, Streblow, Aaron D, Streblow, Cassilyn E, Kreklywich, Craig N, Morrison, Clayton, Sarkar, Sanjay, Moorman, Nathaniel, Sander, Wes, Allen, Robbie, DeFilippis, Victor, Tekwani, Babu L, Wu, Mousheng, Hirsch, Alec J, Smith, Jessica L, Tower, Nichole A, Rasmussen, Lynn, Bostwick, Robert, Maddry, Joseph A, Ananthan, Subramaniam, Gerdes, John M, Augelli-Szafran, Corinne E, Suto, Mark J, Morrison, Thomas E, Heise, Mark T, Streblow, Daniel N, Pathak, Ashish K
Published in Journal of medicinal chemistry (22.04.2021)
Published in Journal of medicinal chemistry (22.04.2021)
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Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses
Powers, John M, Haese, Nicole N, Denton, Michael, Ando, Takeshi, Kreklywich, Craig, Bonin, Kiley, Streblow, Cassilyn E, Kreklywich, Nicholas, Smith, Patricia, Broeckel, Rebecca, DeFilippis, Victor, Morrison, Thomas E, Heise, Mark T, Streblow, Daniel N
Published in PLoS neglected tropical diseases (01.04.2021)
Published in PLoS neglected tropical diseases (01.04.2021)
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The Approved Live-Attenuated Chikungunya Virus Vaccine (IXCHIQ ® ) Elicits Cross-Neutralizing Antibody Breadth Extending to Multiple Arthritogenic Alphaviruses Similar to the Antibody Breadth Following Natural Infection
Weber, Whitney C, Streblow, Zachary J, Kreklywich, Craig N, Denton, Michael, Sulgey, Gauthami, Streblow, Magdalene M, Marcano, Dorca, Flores, Paola N, Rodriguez-Santiago, Rachel M, Alvarado, Luisa I, Rivera-Amill, Vanessa, Messer, William B, Hochreiter, Romana, Kosulin, Karin, Dubischar, Katrin, Buerger, Vera, Streblow, Daniel N
Published in Vaccines (Basel) (07.08.2024)
Published in Vaccines (Basel) (07.08.2024)
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Human Cytomegalovirus Secretome Contains Factors That Induce Angiogenesis and Wound Healing
DUMORTIER, Jerome, STREBLOW, Daniel N, MOSES, Ashlee V, JACOBS, Jon M, KREKLYWICH, Craig N, CAMP, David, SMITH, Richard D, ORLOFF, Susan L, NELSON, Jay A
Published in Journal of Virology (01.07.2008)
Published in Journal of Virology (01.07.2008)
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Nonreciprocity in CHIKV and MAYV Vaccine-Elicited Protection
Weber, Whitney C, Andoh, Takeshi F, Kreklywich, Craig N, Streblow, Zachary J, Denton, Michael, Streblow, Magdalene M, Powers, John M, Sulgey, Gauthami, Medica, Samuel, Dmitriev, Igor, Curiel, David T, Haese, Nicole N, Streblow, Daniel N
Published in Vaccines (Basel) (01.09.2024)
Published in Vaccines (Basel) (01.09.2024)
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