Molecular analysis of circulating tumour cells—biology and biomarkers
Krebs, Matthew G., Metcalf, Robert L., Carter, Louise, Brady, Ged, Blackhall, Fiona H., Dive, Caroline
Published in Nature reviews. Clinical oncology (01.03.2014)
Published in Nature reviews. Clinical oncology (01.03.2014)
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Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study
Park, Keunchil, Haura, Eric B, Leighl, Natasha B, Mitchell, Paul, Shu, Catherine A, Girard, Nicolas, Viteri, Santiago, Han, Ji-Youn, Kim, Sang-We, Lee, Chee Khoon, Sabari, Joshua K, Spira, Alexander I, Yang, Tsung-Ying, Kim, Dong-Wan, Lee, Ki Hyeong, Sanborn, Rachel E, Trigo, José, Goto, Koichi, Lee, Jong-Seok, Yang, James Chih-Hsin, Govindan, Ramaswamy, Bauml, Joshua M, Garrido, Pilar, Krebs, Matthew G, Reckamp, Karen L, Xie, John, Curtin, Joshua C, Haddish-Berhane, Nahor, Roshak, Amy, Millington, Dawn, Lorenzini, Patricia, Thayu, Meena, Knoblauch, Roland E, Cho, Byoung Chul
Published in Journal of clinical oncology (20.10.2021)
Published in Journal of clinical oncology (20.10.2021)
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Ramucirumab plus pembrolizumab in patients with previously treated advanced non-small-cell lung cancer, gastro-oesophageal cancer, or urothelial carcinomas (JVDF): a multicohort, non-randomised, open-label, phase 1a/b trial
Herbst, Roy S, Prof, Arkenau, Hendrik-Tobias, MD, Santana-Davila, Rafael, MD, Calvo, Emiliano, MD, Paz-Ares, Luis, Prof, Cassier, Philippe A, MD, Bendell, Johanna, MD, Penel, Nicolas, Prof, Krebs, Matthew G, MD, Martin-Liberal, Juan, MD, Isambert, Nicolas, MD, Soriano, Andres, MD, Wermke, Martin, MD, Cultrera, Jennifer, MD, Gao, Ling, PhD, Widau, Ryan C, PhD, Mi, Gu, PhD, Jin, Jin, PhD, Ferry, David, MD, Fuchs, Charles S, Prof, Petrylak, Daniel P, Prof, Chau, Ian, MD
Published in The lancet oncology (01.08.2019)
Published in The lancet oncology (01.08.2019)
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Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials
Drilon, Alexander, Siena, Salvatore, Dziadziuszko, Rafal, Barlesi, Fabrice, Krebs, Matthew G, Shaw, Alice T, de Braud, Filippo, Rolfo, Christian, Ahn, Myung-Ju, Wolf, Jürgen, Seto, Takashi, Cho, Byoung Chul, Patel, Manish R, Chiu, Chao-Hua, John, Thomas, Goto, Koichi, Karapetis, Christos S, Arkenau, Hendrick-Tobias, Kim, Sang-We, Ohe, Yuichiro, Li, Yu-Chung, Chae, Young K, Chung, Christine H, Otterson, Gregory A, Murakami, Haruyasu, Lin, Chia-Chi, Tan, Daniel S W, Prenen, Hans, Riehl, Todd, Chow-Maneval, Edna, Simmons, Brian, Cui, Na, Johnson, Ann, Eng, Susan, Wilson, Timothy R, Doebele, Robert C
Published in The lancet oncology (01.02.2020)
Published in The lancet oncology (01.02.2020)
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Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study
Domchek, Susan M, Postel-Vinay, Sophie, Im, Seock-Ah, Park, Yeon Hee, Delord, Jean-Pierre, Italiano, Antoine, Alexandre, Jerome, You, Benoit, Bastian, Sara, Krebs, Matthew G, Wang, Ding, Waqar, Saiama N, Lanasa, Mark, Rhee, Joon, Gao, Haiyan, Rocher-Ros, Vidalba, Jones, Emma V, Gulati, Sakshi, Coenen-Stass, Anna, Kozarewa, Iwanka, Lai, Zhongwu, Angell, Helen K, Opincar, Laura, Herbolsheimer, Pia, Kaufman, Bella
Published in The lancet oncology (01.09.2020)
Published in The lancet oncology (01.09.2020)
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Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer
Hodgkinson, Cassandra L, Morrow, Christopher J, Li, Yaoyong, Metcalf, Robert L, Rothwell, Dominic G, Trapani, Francesca, Polanski, Radoslaw, Burt, Deborah J, Simpson, Kathryn L, Morris, Karen, Pepper, Stuart D, Nonaka, Daisuke, Greystoke, Alastair, Kelly, Paul, Bola, Becky, Krebs, Matthew G, Antonello, Jenny, Ayub, Mahmood, Faulkner, Suzanne, Priest, Lynsey, Carter, Louise, Tate, Catriona, Miller, Crispin J, Blackhall, Fiona, Brady, Ged, Dive, Caroline
Published in Nature medicine (01.08.2014)
Published in Nature medicine (01.08.2014)
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Journal Article
Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer
KREBS, Matthew G, SLOANE, Robert, RANSON, Malcolm, DIVE, Caroline, BLACKHALL, Fiona H, PRIEST, Lynsey, LANCASHIRE, Lee, HOU, Jian-Mei, GREYSTOKE, Alastair, WARD, Tim H, FERRALDESCHI, Roberta, HUGHES, Andrew, CLACK, Glen
Published in Journal of clinical oncology (20.04.2011)
Published in Journal of clinical oncology (20.04.2011)
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Journal Article
Clinical Significance and Molecular Characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in Patients With Small-Cell Lung Cancer
HOU, Jian-Mei, KREBS, Matthew G, WARD, Tim, BLACKHALL, Fiona H, DIVE, Caroline, LANCASHIRE, Lee, SLOANE, Robert, BACKEN, Alison, SWAIN, Rajeeb K, PRIEST, Lynsey J. C, GREYSTOKE, Alastair, CONG ZHOU, MORRIS, Karen
Published in Journal of clinical oncology (10.02.2012)
Published in Journal of clinical oncology (10.02.2012)
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Journal Article
Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation
Sacher, Adrian, LoRusso, Patricia, Patel, Manish R., Miller, Wilson H., Garralda, Elena, Forster, Martin D., Santoro, Armando, Falcon, Alejandro, Kim, Tae Won, Paz-Ares, Luis, Bowyer, Samantha, de Miguel, Maria, Han, Sae-Won, Krebs, Matthew G., Lee, Jong-Seok, Cheng, Michael L., Arbour, Kathryn, Massarelli, Erminia, Choi, Yoonha, Shi, Zhen, Mandlekar, Sandhya, Lin, Mark T., Royer-Joo, Stephanie, Chang, Julie, Dharia, Neekesh V., Schutzman, Jennifer L., Desai, Jayesh
Published in The New England journal of medicine (24.08.2023)
Published in The New England journal of medicine (24.08.2023)
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Web Resource
Ramucirumab Plus Pembrolizumab in Patients with Previously Treated Advanced or Metastatic Biliary Tract Cancer: Nonrandomized, Open‐Label, Phase I Trial (JVDF)
Arkenau, Hendrik‐Tobias, Martin‐Liberal, Juan, Calvo, Emiliano, Penel, Nicolas, Krebs, Matthew G., Herbst, Roy S., Walgren, Richard A., Widau, Ryan C., Mi, Gu, Jin, Jin, Ferry, David, Chau, Ian
Published in The oncologist (Dayton, Ohio) (01.12.2018)
Published in The oncologist (Dayton, Ohio) (01.12.2018)
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Journal Article
Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study
Rothwell, Dominic G., Ayub, Mahmood, Cook, Natalie, Thistlethwaite, Fiona, Carter, Louise, Dean, Emma, Smith, Nigel, Villa, Shaun, Dransfield, Joanne, Clipson, Alexandra, White, Daniel, Nessa, Kamrun, Ferdous, Saba, Howell, Matthew, Gupta, Avinash, Kilerci, Bedirhan, Mohan, Sumitra, Frese, Kris, Gulati, Sakshi, Miller, Crispin, Jordan, Allan, Eaton, Helen, Hickson, Nicholas, O’Brien, Ciara, Graham, Donna, Kelly, Claire, Aruketty, Sreeja, Metcalf, Robert, Chiramel, Jaseela, Tinsley, Nadina, Vickers, Alexander J., Kurup, Roopa, Frost, Hannah, Stevenson, Julie, Southam, Siobhan, Landers, Dónal, Wallace, Andrew, Marais, Richard, Hughes, Andrew M., Brady, Ged, Dive, Caroline, Krebs, Matthew G.
Published in Nature medicine (01.05.2019)
Published in Nature medicine (01.05.2019)
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Journal Article
Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small-Cell Lung Cancer
Dziadziuszko, Rafal, Krebs, Matthew G, De Braud, Filippo, Siena, Salvatore, Drilon, Alexander, Doebele, Robert C, Patel, Manish R, Cho, Byoung Chul, Liu, Stephen V, Ahn, Myung-Ju, Chiu, Chao-Hua, Farago, Anna F, Lin, Chia-Chi, Karapetis, Christos S, Li, Yu-Chung, Day, Bann-Mo, Chen, David, Wilson, Timothy R, Barlesi, Fabrice
Published in Journal of clinical oncology (10.04.2021)
Published in Journal of clinical oncology (10.04.2021)
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Journal Article
Circulating Tumor Cells as a Window on Metastasis Biology in Lung Cancer
Hou, Jian-Mei, Krebs, Matthew, Ward, Tim, Sloane, Robert, Priest, Lynsey, Hughes, Andrew, Clack, Glen, Ranson, Malcolm, Blackhall, Fiona, Dive, Caroline
Published in The American journal of pathology (01.03.2011)
Published in The American journal of pathology (01.03.2011)
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Journal Article
Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches
Krebs, Matthew G., Hou, Jian-Mei, Sloane, Robert, Lancashire, Lee, Priest, Lynsey, Nonaka, Daisuke, Ward, Tim H., Backen, Alison, Clack, Glen, Hughes, Andrew, Ranson, Malcolm, Blackhall, Fiona H., Dive, Caroline
Published in Journal of thoracic oncology (01.02.2012)
Published in Journal of thoracic oncology (01.02.2012)
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Journal Article
Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study
Yap, Timothy A, Krebs, Matthew G, Postel-Vinay, Sophie, El-Khouiery, Anthony, Soria, Jean-Charles, Lopez, Juanita, Berges, Alienor, Cheung, S Y Amy, Irurzun-Arana, Itziar, Goldwin, Andrew, Felicetti, Brunella, Jones, Gemma N, Lau, Alan, Frewer, Paul, Pierce, Andrew J, Clack, Glen, Stephens, Christine, Smith, Simon A, Dean, Emma, Hollingsworth, Simon J
Published in Clinical cancer research (01.10.2021)
Published in Clinical cancer research (01.10.2021)
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Practical Considerations for the Use of Circulating Tumor DNA in the Treatment of Patients With Cancer: A Narrative Review
Krebs, Matthew G, Malapelle, Umberto, André, Fabrice, Paz-Ares, Luis, Schuler, Martin, Thomas, David M, Vainer, Gilad, Yoshino, Takayuki, Rolfo, Christian
Published in JAMA oncology (01.12.2022)
Published in JAMA oncology (01.12.2022)
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Journal Article
Repotrectinib in ROS1 Fusion–Positive Non–Small-Cell Lung Cancer
Drilon, Alexander, Camidge, D. Ross, Lin, Jessica J., Kim, Sang-We, Solomon, Benjamin J., Dziadziuszko, Rafal, Besse, Benjamin, Goto, Koichi, de Langen, Adrianus Johannes, Wolf, Jürgen, Lee, Ki Hyeong, Popat, Sanjay, Springfeld, Christoph, Nagasaka, Misako, Felip, Enriqueta, Yang, Nong, Velcheti, Vamsidhar, Lu, Shun, Kao, Steven, Dooms, Christophe, Krebs, Matthew G., Yao, Wenxiu, Beg, Muhammad Shaalan, Hu, Xiufeng, Moro-Sibilot, Denis, Cheema, Parneet, Stopatschinskaja, Shanna, Mehta, Minal, Trone, Denise, Graber, Armin, Sims, Gregory, Yuan, Yong, Cho, Byoung Chul
Published in The New England journal of medicine (11.01.2024)
Published in The New England journal of medicine (11.01.2024)
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Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib
Coombes, R. C., Howell, Sacha, Lord, Simon R., Kenny, Laura, Mansi, Janine, Mitri, Zahi, Palmieri, Carlo, Chap, Linnea I., Richards, Paul, Gradishar, William, Sardesai, Sagar, Melear, Jason, O’Shaughnessy, Joyce, Ward, Patrick, Chalasani, Pavani, Arkenau, Tobias, Baird, Richard D., Jeselsohn, Rinath, Ali, Simak, Clack, Glen, Bahl, Ashwani, McIntosh, Stuart, Krebs, Matthew G.
Published in Nature communications (24.07.2023)
Published in Nature communications (24.07.2023)
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A cfDNA methylation-based tissue-of-origin classifier for cancers of unknown primary
Conway, Alicia-Marie, Pearce, Simon P., Clipson, Alexandra, Hill, Steven M., Chemi, Francesca, Slane-Tan, Dan, Ferdous, Saba, Hossain, A. S. Md Mukarram, Kamieniecka, Katarzyna, White, Daniel J., Mitchell, Claire, Kerr, Alastair, Krebs, Matthew G., Brady, Gerard, Dive, Caroline, Cook, Natalie, Rothwell, Dominic G.
Published in Nature communications (17.04.2024)
Published in Nature communications (17.04.2024)
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